MAFG and CHD3

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		MAFG	CHD3
Description		MAF bZIP transcription factor G	chromodomain helicase DNA binding protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm RNA Polymerase II Transcription Regulator Complex	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm Centrosome Cytoskeleton NuRD Complex PML Body Centriolar Satellite
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific Double-stranded DNA Binding	Nucleotide Binding Transcription Cis-regulatory Region Binding DNA Binding Chromatin Binding RNA Binding Helicase Activity Protein Binding ATP Binding Zinc Ion Binding Hydrolase Activity ATP Hydrolysis Activity Histone Binding Metal Ion Binding ATP-dependent Chromatin Remodeler Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Adult Behavior Regulation Of Cell Population Proliferation Regulation Of Epidermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Spindle Organization Centrosome Cycle Regulation Of Cell Fate Specification Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Regulation Of Stem Cell Differentiation
Pathways		Nuclear events mediated by NFE2L2 NFE2L2 regulates pentose phosphate pathway genes Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production	HDACs deacetylate histones ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression SUMOylation of chromatin organization proteins Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription Potential therapeutics for SARS Regulation of endogenous retroelements by KRAB-ZFP proteins Transcriptional regulation of brown and beige adipocyte differentiation by EBF2 Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs)
Drugs
Diseases
GWAS			Ischemic stroke ( 26089329) Macular thickness ( 30535121) Prostate cancer ( 29892016) Refractive error ( 32231278) Stroke ( 26089329)
Interacting Genes		24 interacting genes: ATF3 BATF3 CHD3 CREBBP CYP2E1 DDIT3 GTF2A1L HIF1A HOMEZ HOXD12 MAF MAPK3 MED31 NFE2 NFE2L1 NFE2L2 NFIL3 PAX6 PIDD1 PPP1CA PRRX1 RBM48 SNRPN VIM	101 interacting genes: ACTR1B ADH5 AIMP2 ATP5IF1 BARD1 BCL6 BHLHE40 C4orf17 CASP6 CASP8 CBX4 CPE CRCT1 CREB1 CREBBP CSTF2 CTBP1 CTTN ENTR1 ETV5 FABP4 FBP2 FUBP1 GADD45A GIT1 GPS2 GSK3B HABP4 HSD17B10 HSPH1 HTT IK IKZF1 IKZF3 IMMT IVNS1ABP KIF15 KPNA2 KPNB1 LRIF1 LUC7L2 MAFG MAN2A2 MX1 MYB NEFL NR1H2 NR4A1 PAICS PCMT1 PIAS1 PIAS4 PLK4 PRG2 PRPF40A PSME1 PTN PTPRS PUF60 RAD51 RETREG2 RGS2 RIF1 RNF10 RPL29 SAFB SAT1 SATB1 SERBP1 SERF2 SETX SGSM2 SIRT6 SKIL SLC27A6 SPOP SRRT STIP1 SUMO1 SUMO2 TAL1 TCERG1 THOC7 TNFRSF14 TNNT1 TP53 TP73 TRIM28 TRIM54 TSC22D1 TSPAN6 TTR TXNDC9 UBA3 UBC UBE2I UROD VIM XRCC4 YAE1 ZHX1
Entrez ID		4097	1107
HPRD ID		03605	09071
Ensembl ID		ENSG00000197063	ENSG00000170004
Uniprot IDs		O15525	A0A8V8TR54 B3KWV4 Q12873 Q2TAZ1
PDB IDs		7X5E 7X5F 7X5G
Enriched GO Terms of Interacting Partners?		Chromatin RNA Polymerase II Transcription Regulator Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Integrated Stress Response Signaling DNA Binding DNA-binding Transcription Factor Activity Regulation Of Gene Expression Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Nucleus Negative Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Cellular Response To Stress Nucleoplasm Regulation Of Metabolic Process DNA-templated Transcription DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific CHOP-ATF3 Complex Transcription By RNA Polymerase II RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Astrocyte Differentiation Negative Regulation Of Biosynthetic Process Cellular Response To Cytokine Stimulus Negative Regulation Of Metabolic Process Embryonic Morphogenesis Transcription Cis-regulatory Region Binding Cell Redox Homeostasis	Nucleoplasm Nucleus Negative Regulation Of Transcription By RNA Polymerase II Identical Protein Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Biosynthetic Process SUMO Transferase Activity Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process PML Body Protein Sumoylation Regulation Of DNA-templated Transcription Negative Regulation Of Metabolic Process Regulation Of RNA Biosynthetic Process Cytoplasm Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Apoptotic Process Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Programmed Cell Death RNA Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Gene Expression Ubiquitin Protein Ligase Binding Regulation Of Cell Development Presynaptic Cytosol Postsynaptic Cytosol Enzyme Binding Positive Regulation Of Metabolic Process Nucleic Acid Metabolic Process Nuclear Speck Regulation Of Neurogenesis Macromolecule Metabolic Process DNA Repair Positive Regulation Of Macromolecule Metabolic Process Regulation Of Gliogenesis Protein-containing Complex Regulation Of Proteolysis Positive Regulation Of Neuron Apoptotic Process Regulation Of Cellular Response To Stress Regulation Of Cell Differentiation Transcription Corepressor Activity Promoter-specific Chromatin Binding
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