MAFG and GTF2A1L

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		MAFG	GTF2A1L
Description		MAF bZIP transcription factor G	general transcription factor IIA subunit 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm RNA Polymerase II Transcription Regulator Complex	Male Germ Cell Nucleus Nucleus Transcription Factor TFIIA Complex Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Transcription Coactivator Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II In Utero Embryonic Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Adult Behavior Regulation Of Cell Population Proliferation Regulation Of Epidermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Positive Regulation Of DNA-templated Transcription Cognition
Pathways		Nuclear events mediated by NFE2L2 NFE2L2 regulates pentose phosphate pathway genes Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Adult body size ( 32376654) Hepcidin/ferritin ratio ( 27846281) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Joint mobility (Beighton score) ( 27182965) Laterality in neovascular age-related macular degeneration ( 28775256) Polycystic ovary syndrome ( 21151128)
Interacting Genes		24 interacting genes: ATF3 BATF3 CHD3 CREBBP CYP2E1 DDIT3 GTF2A1L HIF1A HOMEZ HOXD12 MAF MAPK3 MED31 NFE2 NFE2L1 NFE2L2 NFIL3 PAX6 PIDD1 PPP1CA PRRX1 RBM48 SNRPN VIM	25 interacting genes: ASCL3 ATF4 CEBPE CSNK2A1 CSNK2A2 EMX1 EMX2 GAB1 GTF2A2 HMG20A HOXA5 HOXC11 HOXC9 ID3 MAFF MAFG NKX2-3 PAX9 RBFOX2 SIX6 SUB1 TBP TLX2 TLX3 ZBTB3
Entrez ID		4097	11036
HPRD ID		03605	05640
Ensembl ID		ENSG00000197063	ENSG00000242441
Uniprot IDs		O15525	Q9UNN4
PDB IDs		7X5E 7X5F 7X5G
Enriched GO Terms of Interacting Partners?		Chromatin RNA Polymerase II Transcription Regulator Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Integrated Stress Response Signaling DNA Binding DNA-binding Transcription Factor Activity Regulation Of Gene Expression Positive Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Nucleus Negative Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Cellular Response To Stress Nucleoplasm Regulation Of Metabolic Process DNA-templated Transcription DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific CHOP-ATF3 Complex Transcription By RNA Polymerase II RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Astrocyte Differentiation Negative Regulation Of Biosynthetic Process Cellular Response To Cytokine Stimulus Negative Regulation Of Metabolic Process Embryonic Morphogenesis Transcription Cis-regulatory Region Binding Cell Redox Homeostasis	Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Sequence-specific Double-stranded DNA Binding Regulation Of RNA Metabolic Process Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding Regulation Of Primary Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Gene Expression Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Nucleus Positive Regulation Of Transcription By RNA Polymerase II Animal Organ Morphogenesis Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Animal Organ Development Developmental Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Protein Kinase CK2 Complex System Development Positive Regulation Of Metabolic Process Anatomical Structure Morphogenesis Transcription Factor TFIIA Complex DNA-templated Transcription Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cerebral Cortex Regionalization Regionalization RNA Polymerase II General Transcription Initiation Factor Binding Central Nervous System Development Nucleoplasm Anterior/posterior Pattern Specification RNA Metabolic Process Positive Regulation Of Transcription Initiation By RNA Polymerase II Neuron Differentiation Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Nucleobase-containing Compound Biosynthetic Process Embryonic Skeletal System Morphogenesis
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