C16orf74 and UNC119

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		C16orf74	UNC119
Gene Name		chromosome 16 open reading frame 74	unc-119 homolog (C. elegans)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Spindle Pole Centrosome Cytosol Intercellular Bridge Spindle Midzone
	Molecular Function		Protein Binding Lipid Binding
	Biological Process		Endocytosis Cytokinesis, Completion Of Separation Synaptic Transmission Visual Perception Phototransduction Lipoprotein Transport Positive Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Clathrin-mediated Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: PPP3CA UNC119	92 interactors: AAGAB ALDH2 AMOT ANKRD24 ANXA1 ANXA3 ANXA7 ARL15 ARL2 ARL3 ARL4D ASH2L BCR BRIX1 BTBD2 C16orf74 CBX8 CCL18 CD247 CD3E CD4 CDC42 CDKN1A CDKN2C CETN3 CKMT2 CKS2 COX17 CYB561D2 EIF2S2 ERH FKBPL FXYD6 FYN GIPC2 GSTM4 HCK HLA-DQA1 HMGB1 HSPB3 HSPE1 ID2 IL5RA ITSN1 KDM1A LAMA4 LCK LIG4 LUC7L2 LYN MAPK10 MAPK8IP2 MPHOSPH6 MRPS12 ORAI2 PAFAH1B3 PAPSS1 PCDHA4 PFN1 PHF10 PIN1 PPA1 PPAP2C PSMD11 PSMD2 PTPRS QTRT1 RAP1B RCC1 RFC5 RGL2 RPA2 RPS6KA5 RUFY3 S100A4 S100A8 SAT1 SEPHS1 SERPINB9 SMN1 SULT1E1 TK1 TP53BP2 TP53I3 TRDMT1 TSC22D1 UBE2B UBE2I UBQLN4 ZAK ZFP64 ZNF24
Entrez ID		404550	9094
HPRD ID		14460	04927
Ensembl ID		ENSG00000154102	ENSG00000109103
Uniprot IDs		Q96GX8	Q13432
PDB IDs			3GQQ 3RBQ 4GOJ 4GOK
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Clathrin-mediated Endocytosis Transition Between Fast And Slow Fiber Negative Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Cytokinesis, Completion Of Separation Negative Regulation Of Transport Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Calcineurin-NFAT Signaling Cascade Regulation Of Skeletal Muscle Adaptation Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of NFAT Protein Import Into Nucleus Mitotic Cytokinetic Process Synaptic Transmission Mitotic Cell Cycle Process Regulation Of Clathrin-mediated Endocytosis Mitotic Cell Cycle Inositol Phosphate-mediated Signaling Positive Regulation Of Cardiac Muscle Hypertrophy Cell-cell Signaling Cell Separation After Cytokinesis Negative Regulation Of Receptor-mediated Endocytosis Lipoprotein Transport Skeletal Muscle Fiber Development Cell Cycle Process Myotube Cell Development Regulation Of Cardiac Muscle Hypertrophy Response To Amphetamine Negative Regulation Of Insulin Secretion Positive Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Transcription Factor Import Into Nucleus Cell Cycle Negative Regulation Of Peptide Secretion Protein Transport Mitotic Cytokinesis Negative Regulation Of Endocytosis Establishment Of Protein Localization Muscle Fiber Development Response To Amine Cellular Response To Drug Myotube Differentiation Cellular Response To Glucose Stimulus Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Hormone Secretion Regulation Of Excitatory Postsynaptic Membrane Potential Cellular Glucose Homeostasis Regulation Of Postsynaptic Membrane Potential Cellular Response To Carbohydrate Stimulus Protein Localization Multicellular Organismal Response To Stress Regulation Of Transcription Factor Import Into Nucleus	T Cell Costimulation Regulation Of Catalytic Activity Response To Stress Developmental Process Immune System Process Regulation Of Defense Response To Virus By Virus System Development Anatomical Structure Development Positive Regulation Of Catalytic Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Response To Stimulus Immune Response Regulation Of Apoptotic Process Defense Response Cell Cycle Nervous System Development Regulation Of Cellular Protein Metabolic Process Multicellular Organismal Development Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Death Intracellular Signal Transduction Regulation Of Protein Metabolic Process Cellular Response To Stimulus Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Immune System Process Positive Regulation Of Transferase Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of T Cell Activation Regulation Of Cell Activation Regulation Of Cell Cycle Innate Immune Response Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell Activation Regulation Of Lymphocyte Activation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell-cell Adhesion Leukocyte Differentiation T Cell Receptor Signaling Pathway Regulation Of Cellular Component Organization Positive Regulation Of Protein Modification Process Viral Process Positive Regulation Of Intracellular Signal Transduction Cell Differentiation Positive Regulation Of Metabolic Process Cell Activation
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