LCK and CCR5

  • Number of citations of the paper that reports this interaction (PMID 11591716)
  • 9
  • Data Source:
  • HPRD (in vivo)

LCK

CCR5

Gene Name LCK proto-oncogene, Src family tyrosine kinase chemokine (C-C motif) receptor 5 (gene/pseudogene)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 122 interactors: ACP1 ADAM15 AJUBA ARHGAP17 AXL BCAR1 BRCA1 CBL CCR5 CD2 CD247 CD28 CD38 CD3E CD4 CD44 CD48 CD5 CD55 CD79A CD79B CD8A CDC25C CDC42 CDKAL1 CSF2RB CSF3R CSK CSNK2B CTLA4 CTNND1 CTNND2 DAPP1 DEF6 DLG1 DOK1 DOK2 DOK3 ESR1 ESR2 EZR FAM174A FAS FASLG FCGR3A G3BP1 GAB2 GRAP HSP90AA1 IFNAR1 IKBKG IL2RB ITK JAK3 KHDRBS1 KIR2DL3 KIT LAT LAX1 LCP2 LIME1 LZTS2 MAPK1 MAPK3 MED28 MS4A1 MUC1 NEDD9 NFKBIA NOTCH1 NR2F2 NR3C1 PAG1 PAK2 PECAM1 PI4KA PIK3CA PIK3R1 PLCG1 PLCG2 PLD2 PRKACA PRKCA PRKCD PRKCQ PTK2 PTK2B PTPN11 PTPN22 PTPN6 PTPRC PTPRF PTPRH PXN RAF1 RASA1 SH2B3 SH2D1A SH2D2A SH3BP2 SHC1 SIT1 SKAP1 SMAD2 SMAD3 SOS1 SQSTM1 STAT1 STAT3 STAT5A SYK THY1 TRAT1 TRPV4 TUB UBE3A UHRF2 UNC119 VAV1 WAS WASL ZAP70 41 interactors: ADRBK1 ADRBK2 AFP ARL6IP5 ARRB1 CCL11 CCL13 CCL14 CCL16 CCL2 CCL3 CCL3L1 CCL3L3 CCL4 CCL5 CCL7 CCL8 CD4 CST9L CTBP2 CXCR4 DNM2 ETV5 GNAI1 GNAI2 GNAI3 GNAO1 GNAQ IL24 JAK1 JAK2 LCK ORM1 PRAF2 PSMA5 PTK2 PTK2B STAT1 STAT3 STAT5A TXK
Entrez ID 3932 1234
HPRD ID 01080 03223
Ensembl ID ENSG00000182866 ENSG00000160791
Uniprot IDs P06239 A0A502 P51681 Q38L21
PDB IDs 1BHF 1BHH 1CWD 1CWE 1FBZ 1H92 1IJR 1KIK 1LCJ 1LCK 1LKK 1LKL 1Q68 1Q69 1QPC 1QPD 1QPE 1QPJ 1X27 2IIM 2OF2 2OF4 2OFU 2OFV 2OG8 2PL0 2ZM1 2ZM4 2ZYB 3AC1 3AC2 3AC3 3AC4 3AC5 3AC8 3ACJ 3ACK 3AD4 3AD5 3AD6 3B2W 3BRH 3BYM 3BYO 3BYS 3BYU 3KMM 3KXZ 3LCK 3MPM 4D8K 1ND8 1NE0 1OPN 1OPT 1OPW 2L87 2RLL 2RRS 4MBS
Enriched GO Terms of Interacting Partners?
Tagcloud ?
amphibian  amphibians  assume  definitive  deoxynucleotidyl  ectotherms  elasmobranchs  elegant  extraembryonic  gata  gnathostomes  grafting  hematopoiesis  icm  ikaros  intraembryonic  leydig  lymphopoiesis  mesoderm  myeloblastosis  oellacher  primitive  rag  spiral  tdt  teleosts  thymopoietic  undeniably  vertebrates 
7b11  aminoxypentane  augmented  broadening  ccr1  ccr2  ccr3  chemokine  chemokines  chemotactic  cxc  cxcr1  eotaxin  hcc2  leukocytes  mcp  migrate  migrated  mip  monocyte  orienting  pmn  polymorphonuclear  prototypic  rantes  reorients  speculate  th1  th2 
Tagcloud (Difference) ?
amphibian  amphibians  assume  definitive  deoxynucleotidyl  ectotherms  elasmobranchs  elegant  extraembryonic  gata  gnathostomes  grafting  hematopoiesis  icm  ikaros  intraembryonic  leydig  lymphopoiesis  mesoderm  myeloblastosis  oellacher  primitive  rag  spiral  tdt  teleosts  thymopoietic  undeniably  vertebrates 
7b11  aminoxypentane  augmented  broadening  ccr1  ccr2  ccr3  chemokine  chemokines  chemotactic  cxc  cxcr1  eotaxin  hcc2  leukocytes  mcp  migrate  migrated  mip  monocyte  orienting  pmn  polymorphonuclear  prototypic  rantes  reorients  speculate  th1  th2 
Tagcloud (Intersection) ?