LCK and STAT1

  • Number of citations of the paper that reports this interaction (PMID 7543024)
  • 347
  • Data Source:
  • HPRD (in vivo, in vitro)

LCK

STAT1

Gene Name LCK proto-oncogene, Src family tyrosine kinase signal transducer and activator of transcription 1, 91kDa
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions 122 interactors: ACP1 ADAM15 AJUBA ARHGAP17 AXL BCAR1 BRCA1 CBL CCR5 CD2 CD247 CD28 CD38 CD3E CD4 CD44 CD48 CD5 CD55 CD79A CD79B CD8A CDC25C CDC42 CDKAL1 CSF2RB CSF3R CSK CSNK2B CTLA4 CTNND1 CTNND2 DAPP1 DEF6 DLG1 DOK1 DOK2 DOK3 ESR1 ESR2 EZR FAM174A FAS FASLG FCGR3A G3BP1 GAB2 GRAP HSP90AA1 IFNAR1 IKBKG IL2RB ITK JAK3 KHDRBS1 KIR2DL3 KIT LAT LAX1 LCP2 LIME1 LZTS2 MAPK1 MAPK3 MED28 MS4A1 MUC1 NEDD9 NFKBIA NOTCH1 NR2F2 NR3C1 PAG1 PAK2 PECAM1 PI4KA PIK3CA PIK3R1 PLCG1 PLCG2 PLD2 PRKACA PRKCA PRKCD PRKCQ PTK2 PTK2B PTPN11 PTPN22 PTPN6 PTPRC PTPRF PTPRH PXN RAF1 RASA1 SH2B3 SH2D1A SH2D2A SH3BP2 SHC1 SIT1 SKAP1 SMAD2 SMAD3 SOS1 SQSTM1 STAT1 STAT3 STAT5A SYK THY1 TRAT1 TRPV4 TUB UBE3A UHRF2 UNC119 VAV1 WAS WASL ZAP70 103 interactors: ACTN4 ADRA1B AKT1 ATF3 BMX BRCA1 CAMK2D CAMK2G CASP3 CASP7 CCR1 CCR5 CREBBP CSE1L CSF2RB CXCR4 DCTN1 DDB1 DOT1L DUSP3 E2F1 EGFR EIF1AD EIF2AK2 ELP2 EP300 ERBB2 FADD FANCC FGFR3 FGFR4 FLT1 FOS FYN GFAP GNB2L1 GTF2I HADH HLA-B HSF1 HSP90AB1 IFNAR2 IFNGR1 IL27RA IL2RB IL2RG IRF1 IRF2 IRF9 JAK1 JAK2 JUN KDR KIT KPNA1 KPNA6 LCK LMO2 LZTR1 MAPK14 MAVS MCM3 MCM5 MDK ND4L NMI NOMO1 NOMO2 OTUD4 PDGFRA PDGFRB PIAS1 PIK3CA POR PRKCD PRMT1 PRMT3 PTK2 PTPN11 PTPN2 RAC1 RELA RPS6KA5 RXRA SHANK1 SPTAN1 SPTBN1 SRC STAT2 STAT3 STAT5A STAT5B SUMO4 SYK TNFRSF1A TNFRSF1B TRADD TYK2 UBC UBE2I VDR XPO1 ZNF467
Entrez ID 3932 6772
HPRD ID 01080 02777
Ensembl ID ENSG00000182866 ENSG00000115415
Uniprot IDs P06239 J3KPM9 P42224
PDB IDs 1BHF 1BHH 1CWD 1CWE 1FBZ 1H92 1IJR 1KIK 1LCJ 1LCK 1LKK 1LKL 1Q68 1Q69 1QPC 1QPD 1QPE 1QPJ 1X27 2IIM 2OF2 2OF4 2OFU 2OFV 2OG8 2PL0 2ZM1 2ZM4 2ZYB 3AC1 3AC2 3AC3 3AC4 3AC5 3AC8 3ACJ 3ACK 3AD4 3AD5 3AD6 3B2W 3BRH 3BYM 3BYO 3BYS 3BYU 3KMM 3KXZ 3LCK 3MPM 4D8K 1BF5 1YVL 2KA6
Enriched GO Terms of Interacting Partners?
Tagcloud ?
amphibian  amphibians  assume  definitive  deoxynucleotidyl  ectotherms  elasmobranchs  elegant  extraembryonic  gata  gnathostomes  grafting  hematopoiesis  icm  ikaros  intraembryonic  leydig  lymphopoiesis  mesoderm  myeloblastosis  oellacher  primitive  rag  spiral  tdt  teleosts  thymopoietic  undeniably  vertebrates 
augment  augments  bait  cbp  coactivator  coil  coiled  enhances  except  hybrid  ifngamma  instead  interactor  interacts  interestingly  intrinsic  lacks  myc  nmi  potentiate  recruitment  reveal  screen  stat2  stat5  stat5b  stats  yeast 
Tagcloud (Difference) ?
amphibian  amphibians  assume  definitive  deoxynucleotidyl  ectotherms  elasmobranchs  elegant  extraembryonic  gata  gnathostomes  grafting  hematopoiesis  icm  ikaros  intraembryonic  leydig  lymphopoiesis  mesoderm  myeloblastosis  oellacher  primitive  rag  spiral  tdt  teleosts  thymopoietic  undeniably  vertebrates 
augment  augments  bait  cbp  coactivator  coil  coiled  enhances  except  hybrid  ifngamma  instead  interactor  interacts  interestingly  intrinsic  lacks  myc  nmi  potentiate  recruitment  reveal  screen  stat2  stat5  stat5b  stats  yeast 
Tagcloud (Intersection) ?