LCK and WASL

  • Number of citations of the paper that reports this interaction (PMID 16293614)
  • 34
  • Data Source:
  • BioGRID (enzymatic study)

LCK

WASL

Gene Name LCK proto-oncogene, Src family tyrosine kinase Wiskott-Aldrich syndrome-like
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 122 interactors: ACP1 ADAM15 AJUBA ARHGAP17 AXL BCAR1 BRCA1 CBL CCR5 CD2 CD247 CD28 CD38 CD3E CD4 CD44 CD48 CD5 CD55 CD79A CD79B CD8A CDC25C CDC42 CDKAL1 CSF2RB CSF3R CSK CSNK2B CTLA4 CTNND1 CTNND2 DAPP1 DEF6 DLG1 DOK1 DOK2 DOK3 ESR1 ESR2 EZR FAM174A FAS FASLG FCGR3A G3BP1 GAB2 GRAP HSP90AA1 IFNAR1 IKBKG IL2RB ITK JAK3 KHDRBS1 KIR2DL3 KIT LAT LAX1 LCP2 LIME1 LZTS2 MAPK1 MAPK3 MED28 MS4A1 MUC1 NEDD9 NFKBIA NOTCH1 NR2F2 NR3C1 PAG1 PAK2 PECAM1 PI4KA PIK3CA PIK3R1 PLCG1 PLCG2 PLD2 PRKACA PRKCA PRKCD PRKCQ PTK2 PTK2B PTPN11 PTPN22 PTPN6 PTPRC PTPRF PTPRH PXN RAF1 RASA1 SH2B3 SH2D1A SH2D2A SH3BP2 SHC1 SIT1 SKAP1 SMAD2 SMAD3 SOS1 SQSTM1 STAT1 STAT3 STAT5A SYK THY1 TRAT1 TRPV4 TUB UBE3A UHRF2 UNC119 VAV1 WAS WASL ZAP70 47 interactors: ABL1 ACTG1 ACTR2 ACTR3 APBB1 APP ARPC3 BAIAP2 CDC42 CTTN DNMBP EVL FCHSD2 FNBP1 FNBP1L GRB2 HP HSP90AA1 HSP90AB1 IPO5 ITSN1 ITSN2 LCK NCK1 NCK2 NCKIPSD PACSIN1 PACSIN2 PACSIN3 PFN1 PRPF40A PSTPIP1 PTK6 RHOJ RHOQ RNF8 RPL7AP66 SDCBP SH3GL3 SNX9 SRC TRIP10 VASP VIPR1 WIPF1 WIPF2 ZNF395
Entrez ID 3932 8976
HPRD ID 01080 05448
Ensembl ID ENSG00000182866 ENSG00000106299
Uniprot IDs P06239 O00401
PDB IDs 1BHF 1BHH 1CWD 1CWE 1FBZ 1H92 1IJR 1KIK 1LCJ 1LCK 1LKK 1LKL 1Q68 1Q69 1QPC 1QPD 1QPE 1QPJ 1X27 2IIM 2OF2 2OF4 2OFU 2OFV 2OG8 2PL0 2ZM1 2ZM4 2ZYB 3AC1 3AC2 3AC3 3AC4 3AC5 3AC8 3ACJ 3ACK 3AD4 3AD5 3AD6 3B2W 3BRH 3BYM 3BYO 3BYS 3BYU 3KMM 3KXZ 3LCK 3MPM 4D8K 2FF3 2LNH 2VCP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
amphibian  amphibians  assume  definitive  deoxynucleotidyl  ectotherms  elasmobranchs  elegant  extraembryonic  gata  gnathostomes  grafting  hematopoiesis  icm  ikaros  intraembryonic  leydig  lymphopoiesis  mesoderm  myeloblastosis  oellacher  primitive  rag  spiral  tdt  teleosts  thymopoietic  undeniably  vertebrates 
148a  biomarker  biopsies  cg  consensus  consequences  downregulated  dysregulated  ectopic  emsa  hypermethylation  integrin  methylated  micrornas  mir  mirna  mirnas  nasopharyngeal  np  npc  oncogenes  pivotal  rock1  stimulatory  supporting  suppressing  unmethylated  usf1  vav2 
Tagcloud (Difference) ?
amphibian  amphibians  assume  definitive  deoxynucleotidyl  ectotherms  elasmobranchs  elegant  extraembryonic  gata  gnathostomes  grafting  hematopoiesis  icm  ikaros  intraembryonic  leydig  lymphopoiesis  mesoderm  myeloblastosis  oellacher  primitive  rag  spiral  tdt  teleosts  thymopoietic  undeniably  vertebrates 
148a  biomarker  biopsies  cg  consensus  consequences  downregulated  dysregulated  ectopic  emsa  hypermethylation  integrin  methylated  micrornas  mir  mirna  mirnas  nasopharyngeal  np  npc  oncogenes  pivotal  rock1  stimulatory  supporting  suppressing  unmethylated  usf1  vav2 
Tagcloud (Intersection) ?