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KRT31 and PRKAA2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
KRT31
PRKAA2
Gene Name
keratin 31, type I
protein kinase, AMP-activated, alpha 2 catalytic subunit
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Intermediate Filament
Extracellular Vesicular Exosome
Nucleoplasm
Cytosol
Molecular Function
Structural Constituent Of Cytoskeleton
Chromatin Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
AMP-activated Protein Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Histone Serine Kinase Activity
Metal Ion Binding
[hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity
[acetyl-CoA Carboxylase] Kinase Activity
Biological Process
Epidermis Development
Energy Reserve Metabolic Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Cholesterol Biosynthetic Process
Carnitine Shuttle
Autophagy
Response To Stress
Organelle Organization
Mitochondrion Organization
Cell Cycle Arrest
Signal Transduction
Insulin Receptor Signaling Pathway
Lipid Biosynthetic Process
Positive Regulation Of Autophagy
Wnt Signaling Pathway
Cellular Response To Nutrient Levels
Negative Regulation Of TOR Signaling
Histone-serine Phosphorylation
Cellular Response To Glucose Starvation
Regulation Of Fatty Acid Biosynthetic Process
Glucose Homeostasis
Regulation Of Circadian Rhythm
Negative Regulation Of Apoptotic Process
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Positive Regulation Of Glycolytic Process
Rhythmic Process
Fatty Acid Homeostasis
Membrane Organization
Regulation Of Energy Homeostasis
Pathways
Organelle biogenesis and maintenance
Integration of energy metabolism
Metabolism of lipids and lipoproteins
Regulation of Rheb GTPase activity by AMPK
IRS-mediated signalling
mTOR signalling
Translocation of GLUT4 to the plasma membrane
Import of palmitoyl-CoA into the mitochondrial matrix
mTOR signalling
IGF1R signaling cascade
IRS-related events triggered by IGF1R
Energy dependent regulation of mTOR by LKB1-AMPK
PKB-mediated events
PI3K Cascade
Signaling by Insulin receptor
Fatty acid, triacylglycerol, and ketone body metabolism
Insulin receptor signalling cascade
Regulation of AMPK activity via LKB1
IRS-related events
Mitochondrial biogenesis
IRS-mediated signalling
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
AMPK inhibits chREBP transcriptional activation activity
PKB-mediated events
PI3K Cascade
Drugs
Diseases
GWAS
Lymphocyte counts (
22286170
)
Protein-Protein Interactions
181 interactors:
ABI2
AES
AGR2
ALDH3B1
ALS2CR11
AMOT
AMOTL2
ANKRD36BP1
AQP1
AQP5
ARHGAP35
ARMC7
ARSJ
ASMTL
ASPSCR1
ATG9A
ATN1
ATXN7L1
BEX2
BTC
BYSL
C12orf49
C19orf73
C1orf109
C1orf216
C5orf60
C6orf165
CA6
CARD9
CARKD
CATIP
CCDC112
CCDC120
CCDC17
CCDC93
CCER1
CCHCR1
CCNC
CD33
CDC20B
CDK18
CDKN1A
CEP57
CEP57L1
CEP70
CHCHD2
CHRNG
CLDN2
COA5
COMT
COX5A
COX5B
CRH
CTSG
DGCR6L
DHX37
DMRT3
DTNB
EIF4E2
EXOC8
FAM103A1
FAM110A
FAM124B
FAM71C
FAM74A4
FAM90A1
FARS2
FBF1
FBXW5
FKBP1B
FOXB1
GEM
GFOD1
GLRX3
GNAI2
GNE
GNG10
GNG5
GPS2
GSTP1
HAUS1
HDAC4
HGS
HOXA1
HSPA12B
HSPD1
ICAM4
INPP5D
INPP5K
INSR
JOSD1
KIFC3
KLC1
KLC4
KLHL38
KRT2
KRT5
KRT6A
KRT6B
KRT6C
KRT71
KRT77
KRT79
KRT8
KRT81
KRT83
LATS1
LCE4A
LENG1
LIN37
LINC00238
LINC00526
LMF2
LMO4
LONRF1
MAP3K7CL
MAPKBP1
MARK4
MRPL40
NAV1
NEK6
NPBWR2
OTUB2
P2RX7
PDE4DIP
PGLS
PIN1
PKN1
PPP1R18
PRF1
PRKAA2
PRR19
PSMA1
PSMG2
PSPC1
PTGER3
PTPMT1
RADIL
RCOR3
RIBC1
RPUSD3
RSPH14
SCNM1
SEMA4C
SHC3
SIRPA
SLC15A3
SLC23A1
SLC25A6
SMARCE1
SMCP
SMG9
SNAI1
SNRNP25
SPATA24
SPON2
SRSF2
SSX2IP
TAPBPL
THAP7
TMEM106C
TMEM231
TMSB4X
TRAF4
TROAP
TSG101
TTC23
TXLNA
USHBP1
UTP23
UXT
WDR25
WDYHV1
ZFYVE21
ZNF124
ZNF148
ZNF20
ZNF569
ZNF572
ZNF69
ZNRF2P1
48 interactors:
ABI2
ACACA
ACACB
AES
AIMP2
APPBP2
C19orf47
CCNB1IP1
EEF2K
EPM2A
FOS
GLI1
HMBOX1
HNF4A
HOMEZ
KCTD1
KIF24
KIFC3
KRT31
KRTAP10-3
L3MBTL3
LEP
MYOZ1
NECAB2
NONO
NOTCH2NL
NRAP
NUTM1
PBXIP1
PFKFB2
PRKAB1
PRKAB2
PRKAG1
RBPMS
RFX6
RPTOR
SNW1
STK11
TCF4
TMOD1
TRIP6
TSC22D4
UBE2I
USHBP1
VPS52
WWP1
ZBTB8A
ZNF397
Entrez ID
3881
5563
HPRD ID
03047
02735
Ensembl ID
ENSG00000094796
ENSG00000162409
Uniprot IDs
Q15323
P54646
PDB IDs
2H6D
2LTU
2YZA
3AQV
Enriched GO Terms of Interacting Partners
?
Cellular Process
Organelle Organization
Epidermis Development
Anatomical Structure Development
Developmental Process
Negative Regulation Of Cellular Metabolic Process
Cytoskeleton Organization
Positive Regulation Of Urine Volume
G2/M Transition Of Mitotic Cell Cycle
Gene Expression
Regulation Of Body Fluid Levels
Epithelium Development
RNA Metabolic Process
Regulation Of Interleukin-6 Production
Carbon Dioxide Transport
Response To Organic Substance
Regulation Of Glycolytic Process
Mitotic Cell Cycle Process
Hippo Signaling
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Interleukin-6 Production
Cell Cycle
Negative Regulation Of Intracellular Signal Transduction
Regulation Of Stress-activated MAPK Cascade
Pancreatic Juice Secretion
Microtubule Cytoskeleton Organization
Movement Of Cell Or Subcellular Component
Mitotic Cell Cycle Phase Transition
Regulation Of Mitotic Nuclear Division
Regulation Of MAPK Cascade
Regulation Of Cell Cycle
Regulation Of Generation Of Precursor Metabolites And Energy
Cell Cycle Phase Transition
Multicellular Organismal Development
Bicarbonate Transport
Cell Volume Homeostasis
Cell Death
Death
Interaction With Symbiont
Negative Regulation Of Signaling
Transcription, DNA-templated
Mitotic Cell Cycle
Regulation Of Protein Metabolic Process
Apoptotic Process
Negative Regulation Of Protein Serine/threonine Kinase Activity
Response To Fungus
Cellular Response To Extracellular Stimulus
Cellular Metabolic Process
Programmed Cell Death
RNA Biosynthetic Process
Energy Reserve Metabolic Process
Biosynthetic Process
Regulation Of Metabolic Process
Transcription, DNA-templated
Cell Cycle Arrest
Negative Regulation Of Transcription, DNA-templated
RNA Biosynthetic Process
Insulin Receptor Signaling Pathway
Regulation Of Gene Expression
Negative Regulation Of Nucleic Acid-templated Transcription
Carnitine Shuttle
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Transcription, DNA-templated
Generation Of Precursor Metabolites And Energy
Cellular Response To Hormone Stimulus
Regulation Of Nucleic Acid-templated Transcription
Response To Insulin
Regulation Of RNA Biosynthetic Process
Cellular Macromolecule Biosynthetic Process
Carnitine Transmembrane Transport
Energy Derivation By Oxidation Of Organic Compounds
Macromolecule Biosynthetic Process
Carnitine Transport
Regulation Of RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Gene Expression
Gene Expression
Cellular Response To Insulin Stimulus
Negative Regulation Of Biosynthetic Process
RNA Metabolic Process
Malonyl-CoA Biosynthetic Process
Fatty Acid Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Quaternary Ammonium Group Transport
Regulation Of Carbohydrate Metabolic Process
Positive Regulation Of Metabolic Process
Nucleobase-containing Compound Metabolic Process
Regulation Of Lipid Metabolic Process
Response To Peptide Hormone
Heterocycle Metabolic Process
Cellular Response To Peptide Hormone Stimulus
Cellular Aromatic Compound Metabolic Process
Cellular Metabolic Process
Fatty Acid Metabolic Process
Response To Peptide
Cellular Response To Peptide
Regulation Of Insulin Secretion
Glucose Homeostasis
Response To Hormone
Cellular Nitrogen Compound Metabolic Process
Tagcloud
?
amyloidogenesis
apmk
appswe
arc
biogenesis
functionality
igf1
igf2
igfbp2
igfr
impairments
insoluble
insr
intolerant
irs1
irs2
nrf1
oxphos
pampk
pgc
pgc1
plaque
precede
ps1
ps1de9
reinforce
sensors
tfam
thr172
Tagcloud (Difference)
?
amyloidogenesis
apmk
appswe
arc
biogenesis
functionality
igf1
igf2
igfbp2
igfr
impairments
insoluble
insr
intolerant
irs1
irs2
nrf1
oxphos
pampk
pgc
pgc1
plaque
precede
ps1
ps1de9
reinforce
sensors
tfam
thr172
Tagcloud (Intersection)
?