KRT31 and FKBP1B

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRT31	FKBP1B
Gene Name		keratin 31, type I	FK506 binding protein 1B, 12.6 kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Intermediate Filament Extracellular Vesicular Exosome	Cytoplasm Cytosol Membrane Z Disc Sarcoplasmic Reticulum Membrane Calcium Channel Complex
	Molecular Function	Structural Constituent Of Cytoskeleton	Peptidyl-prolyl Cis-trans Isomerase Activity Receptor Binding Ryanodine-sensitive Calcium-release Channel Activity Protein Binding FK506 Binding Calcium Channel Inhibitor Activity Cyclic Nucleotide Binding Ion Channel Binding
	Biological Process	Epidermis Development	Protein Peptidyl-prolyl Isomerization 'de Novo' Protein Folding Smooth Muscle Contraction Response To Glucose Negative Regulation Of Heart Rate Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Neuronal Action Potential Propagation Protein Maturation By Protein Folding Insulin Secretion Negative Regulation Of Protein Phosphatase Type 2B Activity Response To Vitamin E Ion Transmembrane Transport Calcium-mediated Signaling Using Intracellular Calcium Source Protein Refolding T Cell Proliferation Response To Hydrogen Peroxide Positive Regulation Of Axon Regeneration Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Sequestering Of Calcium Ion Cytosolic Calcium Ion Homeostasis Response To Redox State Transmembrane Transport Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Chaperone-mediated Protein Folding Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Calcium Ion Transmembrane Transport Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Pathways			Ion channel transport Stimuli-sensing channels
Drugs
Diseases
GWAS			Quantitative traits ( 19197348)
Protein-Protein Interactions		181 interactors: ABI2 AES AGR2 ALDH3B1 ALS2CR11 AMOT AMOTL2 ANKRD36BP1 AQP1 AQP5 ARHGAP35 ARMC7 ARSJ ASMTL ASPSCR1 ATG9A ATN1 ATXN7L1 BEX2 BTC BYSL C12orf49 C19orf73 C1orf109 C1orf216 C5orf60 C6orf165 CA6 CARD9 CARKD CATIP CCDC112 CCDC120 CCDC17 CCDC93 CCER1 CCHCR1 CCNC CD33 CDC20B CDK18 CDKN1A CEP57 CEP57L1 CEP70 CHCHD2 CHRNG CLDN2 COA5 COMT COX5A COX5B CRH CTSG DGCR6L DHX37 DMRT3 DTNB EIF4E2 EXOC8 FAM103A1 FAM110A FAM124B FAM71C FAM74A4 FAM90A1 FARS2 FBF1 FBXW5 FKBP1B FOXB1 GEM GFOD1 GLRX3 GNAI2 GNE GNG10 GNG5 GPS2 GSTP1 HAUS1 HDAC4 HGS HOXA1 HSPA12B HSPD1 ICAM4 INPP5D INPP5K INSR JOSD1 KIFC3 KLC1 KLC4 KLHL38 KRT2 KRT5 KRT6A KRT6B KRT6C KRT71 KRT77 KRT79 KRT8 KRT81 KRT83 LATS1 LCE4A LENG1 LIN37 LINC00238 LINC00526 LMF2 LMO4 LONRF1 MAP3K7CL MAPKBP1 MARK4 MRPL40 NAV1 NEK6 NPBWR2 OTUB2 P2RX7 PDE4DIP PGLS PIN1 PKN1 PPP1R18 PRF1 PRKAA2 PRR19 PSMA1 PSMG2 PSPC1 PTGER3 PTPMT1 RADIL RCOR3 RIBC1 RPUSD3 RSPH14 SCNM1 SEMA4C SHC3 SIRPA SLC15A3 SLC23A1 SLC25A6 SMARCE1 SMCP SMG9 SNAI1 SNRNP25 SPATA24 SPON2 SRSF2 SSX2IP TAPBPL THAP7 TMEM106C TMEM231 TMSB4X TRAF4 TROAP TSG101 TTC23 TXLNA USHBP1 UTP23 UXT WDR25 WDYHV1 ZFYVE21 ZNF124 ZNF148 ZNF20 ZNF569 ZNF572 ZNF69 ZNRF2P1	9 interactors: ADAMTSL4 BMPR1A CAMK2D GMCL1 KRT31 KRT40 REL RYR2 TRIM69
Entrez ID		3881	2281
HPRD ID		03047	02795
Ensembl ID		ENSG00000094796	ENSG00000119782
Uniprot IDs		Q15323	P68106
PDB IDs			1C9H 4C02
Enriched GO Terms of Interacting Partners?		Cellular Process Organelle Organization Epidermis Development Anatomical Structure Development Developmental Process Negative Regulation Of Cellular Metabolic Process Cytoskeleton Organization Positive Regulation Of Urine Volume G2/M Transition Of Mitotic Cell Cycle Gene Expression Regulation Of Body Fluid Levels Epithelium Development RNA Metabolic Process Regulation Of Interleukin-6 Production Carbon Dioxide Transport Response To Organic Substance Regulation Of Glycolytic Process Mitotic Cell Cycle Process Hippo Signaling Negative Regulation Of Biosynthetic Process Positive Regulation Of Interleukin-6 Production Cell Cycle Negative Regulation Of Intracellular Signal Transduction Regulation Of Stress-activated MAPK Cascade Pancreatic Juice Secretion Microtubule Cytoskeleton Organization Movement Of Cell Or Subcellular Component Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Nuclear Division Regulation Of MAPK Cascade Regulation Of Cell Cycle Regulation Of Generation Of Precursor Metabolites And Energy Cell Cycle Phase Transition Multicellular Organismal Development Bicarbonate Transport Cell Volume Homeostasis Cell Death Death Interaction With Symbiont Negative Regulation Of Signaling Transcription, DNA-templated Mitotic Cell Cycle Regulation Of Protein Metabolic Process Apoptotic Process Negative Regulation Of Protein Serine/threonine Kinase Activity Response To Fungus Cellular Response To Extracellular Stimulus Cellular Metabolic Process Programmed Cell Death RNA Biosynthetic Process	Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cardiac Muscle Hypertrophy Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Muscle Hypertrophy Regulation Of The Force Of Heart Contraction Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Cardiac Muscle Contraction Regulation Of Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Heart Contraction Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction BMP Signaling Pathway Regulation Of Cation Channel Activity Regulation Of Calcium Ion Transport Into Cytosol Regulation Of Intracellular Transport Neural Plate Mediolateral Regionalization Left Ventricular Cardiac Muscle Tissue Morphogenesis Paraxial Mesoderm Structural Organization Positive Regulation Of Calcium-transporting ATPase Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity By Adrenergic Receptor Signaling Pathway Involved In Positive Regulation Of Cardiac Muscle Contraction Striated Muscle Contraction Regulation Of Striated Muscle Contraction Calcium-mediated Signaling Heart Development Positive Regulation Of Sequestering Of Calcium Ion Type B Pancreatic Cell Apoptotic Process Response To Calcium Ion Second-messenger-mediated Signaling Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Cardiac Muscle Cell Contraction Regulation Of Calcium-transporting ATPase Activity Adrenergic Receptor Signaling Pathway Involved In Heart Process Purkinje Myocyte To Ventricular Cardiac Muscle Cell Signaling Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Muscle Contraction Regulation Of Ion Homeostasis Regulation Of Generation Of L-type Calcium Current Mesendoderm Development Regulation Of Lateral Mesodermal Cell Fate Specification Positive Regulation Of The Force Of Heart Contraction G-protein Coupled Receptor Signaling Pathway Involved In Heart Process Regulation Of Heart Contraction Tissue Development Positive Regulation Of Rac Protein Signal Transduction
Tagcloud ?			aav abcc8 adeno administrations cxcl12 cxcl13 damaged foxa2 g6pc2 gad1 glp glucosamine glut2 isl1 islets neurod1 nitrosourea nkx6 nptx2 pdx1 preserve prss53 sdf slc2a2 slc30a8 stz tmem229b ttc28 ucn3
Tagcloud (Difference) ?			aav abcc8 adeno administrations cxcl12 cxcl13 damaged foxa2 g6pc2 gad1 glp glucosamine glut2 isl1 islets neurod1 nitrosourea nkx6 nptx2 pdx1 preserve prss53 sdf slc2a2 slc30a8 stz tmem229b ttc28 ucn3
Tagcloud (Intersection) ?