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P2RX7 and KRT31
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
P2RX7
KRT31
Gene Name
purinergic receptor P2X, ligand gated ion channel, 7
keratin 31, type I
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Integral Component Of Nuclear Inner Membrane
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Cell-cell Junction
External Side Of Plasma Membrane
Membrane
Neuromuscular Junction
Bleb
Neuronal Cell Body
Terminal Bouton
Protein Complex
Membrane Raft
Extracellular Space
Intermediate Filament
Extracellular Vesicular Exosome
Molecular Function
Magnesium Ion Binding
Lipopolysaccharide Binding
Purinergic Nucleotide Receptor Activity
Extracellular ATP-gated Cation Channel Activity
Receptor Binding
Copper Ion Binding
Protein Binding
ATP Binding
Zinc Ion Binding
Protein Homodimerization Activity
Scaffold Protein Binding
Structural Constituent Of Cytoskeleton
Biological Process
Activation Of MAPK Activity
Cell Morphogenesis
Phagolysosome Assembly
Positive Regulation Of T Cell Mediated Cytotoxicity
Regulation Of Sodium Ion Transport
Protein Phosphorylation
Membrane Protein Ectodomain Proteolysis
Phospholipid Transfer To Membrane
Cell Volume Homeostasis
Membrane Budding
Inflammatory Response
Mitochondrion Organization
Plasma Membrane Organization
Cell Surface Receptor Signaling Pathway
Response To Mechanical Stimulus
Response To Zinc Ion
Positive Regulation Of Calcium Ion Transport Into Cytosol
Positive Regulation Of Glutamate Secretion
Positive Regulation Of Gamma-aminobutyric Acid Secretion
Synaptic Vesicle Exocytosis
Protein Processing
Neuronal Action Potential
Sensory Perception Of Pain
Cytolysis
Positive Regulation Of Bone Mineralization
Cellular Response To Extracellular Stimulus
Bleb Assembly
Positive Regulation Of Prostaglandin Secretion
Response To Lipopolysaccharide
Positive Regulation Of Interleukin-6 Production
Collagen Metabolic Process
Response To ATP
Response To Fluid Shear Stress
Purinergic Nucleotide Receptor Signaling Pathway
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
T Cell Proliferation
Response To Drug
T Cell Homeostasis
NAD Transport
Negative Regulation Of MAPK Cascade
Multicellular Organismal Protein Catabolic Process
Innate Immune Response
Phospholipid Translocation
Negative Regulation Of Bone Resorption
Positive Regulation Of Cytolysis
Ceramide Biosynthetic Process
Pore Complex Assembly
Skeletal System Morphogenesis
Homeostasis Of Number Of Cells Within A Tissue
Positive Regulation Of Interleukin-1 Alpha Secretion
Positive Regulation Of Interleukin-1 Beta Secretion
Defense Response To Gram-positive Bacterium
Release Of Sequestered Calcium Ion Into Cytosol
Protein Oligomerization
Positive Regulation Of Cytoskeleton Organization
Response To Calcium Ion
Response To Electrical Stimulus
Regulation Of Killing Of Cells Of Other Organism
Membrane Depolarization
Positive Regulation Of Mitochondrial Depolarization
Positive Regulation Of Lymphocyte Apoptotic Process
Reactive Oxygen Species Metabolic Process
Apoptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway
Cation Transmembrane Transport
Epidermis Development
Pathways
The NLRP3 inflammasome
Inflammasomes
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
Innate Immune System
Drugs
Diseases
GWAS
Chronic obstructive pulmonary disease-related biomarkers (
23144326
)
Protein-Protein Interactions
9 interactors:
ACTB
CASK
EFNB3
EMP3
KRT31
KRTAP10-8
PANX1
SVIL
TM9SF1
181 interactors:
ABI2
AES
AGR2
ALDH3B1
ALS2CR11
AMOT
AMOTL2
ANKRD36BP1
AQP1
AQP5
ARHGAP35
ARMC7
ARSJ
ASMTL
ASPSCR1
ATG9A
ATN1
ATXN7L1
BEX2
BTC
BYSL
C12orf49
C19orf73
C1orf109
C1orf216
C5orf60
C6orf165
CA6
CARD9
CARKD
CATIP
CCDC112
CCDC120
CCDC17
CCDC93
CCER1
CCHCR1
CCNC
CD33
CDC20B
CDK18
CDKN1A
CEP57
CEP57L1
CEP70
CHCHD2
CHRNG
CLDN2
COA5
COMT
COX5A
COX5B
CRH
CTSG
DGCR6L
DHX37
DMRT3
DTNB
EIF4E2
EXOC8
FAM103A1
FAM110A
FAM124B
FAM71C
FAM74A4
FAM90A1
FARS2
FBF1
FBXW5
FKBP1B
FOXB1
GEM
GFOD1
GLRX3
GNAI2
GNE
GNG10
GNG5
GPS2
GSTP1
HAUS1
HDAC4
HGS
HOXA1
HSPA12B
HSPD1
ICAM4
INPP5D
INPP5K
INSR
JOSD1
KIFC3
KLC1
KLC4
KLHL38
KRT2
KRT5
KRT6A
KRT6B
KRT6C
KRT71
KRT77
KRT79
KRT8
KRT81
KRT83
LATS1
LCE4A
LENG1
LIN37
LINC00238
LINC00526
LMF2
LMO4
LONRF1
MAP3K7CL
MAPKBP1
MARK4
MRPL40
NAV1
NEK6
NPBWR2
OTUB2
P2RX7
PDE4DIP
PGLS
PIN1
PKN1
PPP1R18
PRF1
PRKAA2
PRR19
PSMA1
PSMG2
PSPC1
PTGER3
PTPMT1
RADIL
RCOR3
RIBC1
RPUSD3
RSPH14
SCNM1
SEMA4C
SHC3
SIRPA
SLC15A3
SLC23A1
SLC25A6
SMARCE1
SMCP
SMG9
SNAI1
SNRNP25
SPATA24
SPON2
SRSF2
SSX2IP
TAPBPL
THAP7
TMEM106C
TMEM231
TMSB4X
TRAF4
TROAP
TSG101
TTC23
TXLNA
USHBP1
UTP23
UXT
WDR25
WDYHV1
ZFYVE21
ZNF124
ZNF148
ZNF20
ZNF569
ZNF572
ZNF69
ZNRF2P1
Entrez ID
5027
3881
HPRD ID
03977
03047
Ensembl ID
ENSG00000089041
ENSG00000094796
Uniprot IDs
Q99572
Q15323
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cellular Process
Organelle Organization
Epidermis Development
Anatomical Structure Development
Developmental Process
Negative Regulation Of Cellular Metabolic Process
Cytoskeleton Organization
Positive Regulation Of Urine Volume
G2/M Transition Of Mitotic Cell Cycle
Gene Expression
Regulation Of Body Fluid Levels
Epithelium Development
RNA Metabolic Process
Regulation Of Interleukin-6 Production
Carbon Dioxide Transport
Response To Organic Substance
Regulation Of Glycolytic Process
Mitotic Cell Cycle Process
Hippo Signaling
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Interleukin-6 Production
Cell Cycle
Negative Regulation Of Intracellular Signal Transduction
Regulation Of Stress-activated MAPK Cascade
Pancreatic Juice Secretion
Microtubule Cytoskeleton Organization
Movement Of Cell Or Subcellular Component
Mitotic Cell Cycle Phase Transition
Regulation Of Mitotic Nuclear Division
Regulation Of MAPK Cascade
Regulation Of Cell Cycle
Regulation Of Generation Of Precursor Metabolites And Energy
Cell Cycle Phase Transition
Multicellular Organismal Development
Bicarbonate Transport
Cell Volume Homeostasis
Cell Death
Death
Interaction With Symbiont
Negative Regulation Of Signaling
Transcription, DNA-templated
Mitotic Cell Cycle
Regulation Of Protein Metabolic Process
Apoptotic Process
Negative Regulation Of Protein Serine/threonine Kinase Activity
Response To Fungus
Cellular Response To Extracellular Stimulus
Cellular Metabolic Process
Programmed Cell Death
RNA Biosynthetic Process
Tagcloud
?
adam29
cd109
cd248
cgh
chl1
cladogram
crcs
csmd3
ercc6
ergic3
evl
fbxw7
galns
gnas
iranian
lgr
mmp2
msi
msp
mss
parsimony
prkd1
ptprd
rnf182
sfrs6
slc29a1
specifics
syne1
tbx22
Tagcloud (Difference)
?
adam29
cd109
cd248
cgh
chl1
cladogram
crcs
csmd3
ercc6
ergic3
evl
fbxw7
galns
gnas
iranian
lgr
mmp2
msi
msp
mss
parsimony
prkd1
ptprd
rnf182
sfrs6
slc29a1
specifics
syne1
tbx22
Tagcloud (Intersection)
?