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P2RX7
Gene Name
purinergic receptor P2X, ligand gated ion channel, 7
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Integral Component Of Nuclear Inner Membrane
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Cell-cell Junction
External Side Of Plasma Membrane
Membrane
Neuromuscular Junction
Bleb
Neuronal Cell Body
Terminal Bouton
Protein Complex
Membrane Raft
Molecular Function
Magnesium Ion Binding
Lipopolysaccharide Binding
Purinergic Nucleotide Receptor Activity
Extracellular ATP-gated Cation Channel Activity
Receptor Binding
Copper Ion Binding
Protein Binding
ATP Binding
Zinc Ion Binding
Protein Homodimerization Activity
Scaffold Protein Binding
Biological Process
Activation Of MAPK Activity
Cell Morphogenesis
Phagolysosome Assembly
Positive Regulation Of T Cell Mediated Cytotoxicity
Regulation Of Sodium Ion Transport
Protein Phosphorylation
Membrane Protein Ectodomain Proteolysis
Phospholipid Transfer To Membrane
Cell Volume Homeostasis
Membrane Budding
Inflammatory Response
Mitochondrion Organization
Plasma Membrane Organization
Cell Surface Receptor Signaling Pathway
Response To Mechanical Stimulus
Response To Zinc Ion
Positive Regulation Of Calcium Ion Transport Into Cytosol
Positive Regulation Of Glutamate Secretion
Positive Regulation Of Gamma-aminobutyric Acid Secretion
Synaptic Vesicle Exocytosis
Protein Processing
Neuronal Action Potential
Sensory Perception Of Pain
Cytolysis
Positive Regulation Of Bone Mineralization
Cellular Response To Extracellular Stimulus
Bleb Assembly
Positive Regulation Of Prostaglandin Secretion
Response To Lipopolysaccharide
Positive Regulation Of Interleukin-6 Production
Collagen Metabolic Process
Response To ATP
Response To Fluid Shear Stress
Purinergic Nucleotide Receptor Signaling Pathway
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
T Cell Proliferation
Response To Drug
T Cell Homeostasis
NAD Transport
Negative Regulation Of MAPK Cascade
Multicellular Organismal Protein Catabolic Process
Innate Immune Response
Phospholipid Translocation
Negative Regulation Of Bone Resorption
Positive Regulation Of Cytolysis
Ceramide Biosynthetic Process
Pore Complex Assembly
Skeletal System Morphogenesis
Homeostasis Of Number Of Cells Within A Tissue
Positive Regulation Of Interleukin-1 Alpha Secretion
Positive Regulation Of Interleukin-1 Beta Secretion
Defense Response To Gram-positive Bacterium
Release Of Sequestered Calcium Ion Into Cytosol
Protein Oligomerization
Positive Regulation Of Cytoskeleton Organization
Response To Calcium Ion
Response To Electrical Stimulus
Regulation Of Killing Of Cells Of Other Organism
Membrane Depolarization
Positive Regulation Of Mitochondrial Depolarization
Positive Regulation Of Lymphocyte Apoptotic Process
Reactive Oxygen Species Metabolic Process
Apoptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway
Cation Transmembrane Transport
Pathways
The NLRP3 inflammasome
Inflammasomes
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
Innate Immune System
Drugs
Diseases
GWAS
Chronic obstructive pulmonary disease-related biomarkers (
23144326
)
Protein-protein Interactions
9 interactors:
ACTB
CASK
EFNB3
EMP3
KRT31
KRTAP10-8
PANX1
SVIL
TM9SF1
Entrez ID
5027
HPRD ID
03977
Ensembl ID
ENSG00000089041
Uniprot IDs
Q99572
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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adam29
cd109
cd248
cgh
chl1
cladogram
crcs
csmd3
ercc6
ergic3
evl
fbxw7
galns
gnas
iranian
lgr
mmp2
msi
msp
mss
parsimony
prkd1
ptprd
rnf182
sfrs6
slc29a1
specifics
syne1
tbx22