KRTAP10-11 and OTX1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRTAP10-11	OTX1
Gene Name		keratin associated protein 10-11	orthodenticle homeobox 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Keratin Filament	Nucleus
	Molecular Function		RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
	Biological Process		Anterior/posterior Pattern Specification Metencephalon Development Midbrain Development Inner Ear Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Diencephalon Morphogenesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: ADAMTSL4 CAMK2B CATSPER1 CREB5 FAM76B GLRX3 HOXA1 KRTAP4-2 KRTAP5-9 KRTAP9-2 MEOX2 NOTCH2NL OTX1 PLSCR1 SPRY2	39 interactors: CHIC2 CHRD COMP GEMIN8P4 GRN KCNK16 KRT81 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-4 KRTAP26-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE4A MDFI MGAT5B RBPMS RGS17 RGS20 SMARCC1 SPRY1 SPRY2 TLE4
Entrez ID		386678	5013
HPRD ID		11186	08964
Ensembl ID		ENSG00000243489	ENSG00000115507
Uniprot IDs		P60411 P60412	P32242
PDB IDs
Enriched GO Terms of Interacting Partners?		Inner Ear Morphogenesis Ear Morphogenesis Positive Regulation Of Gene Expression Inner Ear Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Ear Development Anterior/posterior Pattern Specification Positive Regulation Of Transcription, DNA-templated Developmental Process Optokinetic Behavior Abducens Nerve Formation Inhibitory G-protein Coupled Receptor Phosphorylation Embryonic Organ Morphogenesis Positive Regulation Of Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Facial Nucleus Development Activation Of Meiosis Involved In Egg Activation Multicellular Organismal Development Positive Regulation Of Cellular Metabolic Process Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Rhombomere 4 Development Semicircular Canal Formation Pattern Specification Process Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Organ Development Rhombomere 3 Development Rhombomere 5 Development Activation Of Meiosis Metencephalon Development Single Fertilization Neuromuscular Process Embryo Development Somite Specification Phosphatidylserine Biosynthetic Process Sensory Perception Of Sound Sensory Organ Development Diencephalon Morphogenesis Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of Synaptic Transmission, Cholinergic Hindbrain Development Fertilization Lung Growth Sensory Perception Of Mechanical Stimulus Embryonic Morphogenesis Embryonic Neurocranium Morphogenesis Regulation Of Calcium Ion Transport Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of Skeletal Muscle Adaptation	Keratinization Keratinocyte Differentiation Epithelium Development Epidermis Development Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Tissue Development Epidermal Cell Differentiation Regulation Of Neurotrophin TRK Receptor Signaling Pathway Bud Elongation Involved In Lung Branching Skin Development Organ Development Developmental Process Negative Regulation Of Ras GTPase Activity Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Anatomical Structure Development Branch Elongation Of An Epithelium Negative Regulation Of Signal Transduction Developmental Growth Involved In Morphogenesis Negative Regulation Of Signaling Negative Regulation Of GTPase Activity Axis Elongation Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Establishment Of Mitotic Spindle Orientation Multicellular Organismal Development Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Epithelial Tube Branching Involved In Lung Morphogenesis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway System Development Spindle Localization BMP Signaling Pathway Involved In Spinal Cord Dorsal/ventral Patterning Epithelial Cell Differentiation Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Ras Protein Signal Transduction Organ Morphogenesis Negative Regulation Of Small GTPase Mediated Signal Transduction Lung Morphogenesis Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Developmental Growth Regulation Of MAP Kinase Activity Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Negative Regulation Of MAP Kinase Activity Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Organ Growth Regulation Of GTPase Activity Negative Regulation Of Cellular Response To Growth Factor Stimulus Establishment Of Cell Polarity
Tagcloud ?			17q21 2p15 allowing amplification antecedent bcl11a cdkn2a cgh commd1 diffuse disrupting dlbcl dndlbcl driver encompassing exclusively fl follicular lymphoma never nfkappabeta novo outline paired possessed rel tdlbcl transformation usp34
Tagcloud (Difference) ?			17q21 2p15 allowing amplification antecedent bcl11a cdkn2a cgh commd1 diffuse disrupting dlbcl dndlbcl driver encompassing exclusively fl follicular lymphoma never nfkappabeta novo outline paired possessed rel tdlbcl transformation usp34
Tagcloud (Intersection) ?