ELAVL1 and PAIP2

Number of citations of the paper that reports this interaction (PMID 15175342)
16

Data Source:
HPRD (in vitro, in vivo)

		ELAVL1	PAIP2
Gene Name		ELAV like RNA binding protein 1	poly(A) binding protein interacting protein 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane	Cytoplasm
	Molecular Function	Nucleotide Binding RNA Binding Double-stranded RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding AU-rich Element Binding Protein Kinase Binding MRNA 3'-UTR AU-rich Region Binding Poly(A) RNA Binding	MRNA Binding Protein Binding Translation Repressor Activity
	Biological Process	Multicellular Organismal Development Gene Expression Positive Regulation Of Translation MRNA Stabilization 3'-UTR-mediated MRNA Stabilization Regulation Of Stem Cell Maintenance	Spermatogenesis Memory Negative Regulation Of Translational Initiation Regulation Of Long-term Synaptic Potentiation
Pathways		Regulation of mRNA stability by proteins that bind AU-rich elements HuR stabilizes mRNA
Drugs
Diseases
GWAS
Protein-Protein Interactions		35 interactors: ANP32A ANP32B APOE CARM1 CELF2 CHEK2 CTNNB1 ERG GJB3 HNRNPK HOTAIR IL7R KPNA1 KPNB1 MIRLET7B MIRLET7I NOS3 PAIP2 PLAU PLAUR PRKCA PRKCD PRKCE PSEN2 PTBP1 PTBP2 PTGS2 RBFOX2 SDCBP SET SREK1 TNPO1 TNPO2 VEGFA XIAP	5 interactors: APP ELAVL1 PABPC1 RPL11 UBR5
Entrez ID		1994	51247
HPRD ID		16025	05726
Ensembl ID		ENSG00000066044	ENSG00000120727
Uniprot IDs		B4DVB8 Q15717	Q9BPZ3
PDB IDs		3HI9 4ED5 4EGL 4FXV	1JGN 3KUS 3KUT
Enriched GO Terms of Interacting Partners?		Regulation Of Wound Healing Regulation Of Blood Coagulation Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Positive Regulation Of Transport Negative Regulation Of Wound Healing Apoptotic Process Regulation Of Protein Metabolic Process Programmed Cell Death Negative Regulation Of Cellular Protein Metabolic Process Cell Death Death Regulation Of Platelet Activation Regulation Of Metabolic Process Cell Communication Signal Transduction Negative Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Ion Transport Regulation Of Nitrogen Compound Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Receptor Activity Signaling Response To Abiotic Stimulus Blood Coagulation Negative Regulation Of Platelet Activation Hemostasis Regulation Of Epithelial Cell Migration Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cellular Response To Stimulus Regulation Of Apoptotic Process Regulation Of Cell Proliferation Response To External Stimulus Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Blood Vessel Endothelial Cell Migration Cellular Response To Organic Substance Regulation Of Cell Death Response To Wounding Blood Circulation Response To Cytokine Execution Phase Of Apoptosis Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Cell Death Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Epithelial Cell Migration Vasculature Development RNA Splicing Regulation Of Peptidyl-tyrosine Phosphorylation	MRNA Stabilization MRNA Polyadenylation Regulation Of Translation RNA Polyadenylation Regulation Of MRNA Stability Regulation Of RNA Stability Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Translation MRNA Metabolic Process MRNA 3'-end Processing Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RNA 3'-end Processing Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Nuclear-transcribed MRNA Catabolic Process Synaptic Growth At Neuromuscular Junction MRNA Catabolic Process Cellular Macromolecule Catabolic Process RNA Catabolic Process Collateral Sprouting In Absence Of Injury Negative Regulation Of Histone H2A K63-linked Ubiquitination Intracellular Receptor Signaling Pathway Regulation Of Histone Ubiquitination Negative Regulation Of Protein K63-linked Ubiquitination Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translational Initiation Positive Regulation Of Cellular Protein Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Protein K63-linked Ubiquitination Progesterone Receptor Signaling Pathway Positive Regulation Of Protein Metabolic Process Axon Choice Point Recognition Negative Regulation Of Double-strand Break Repair Negative Regulation Of DNA Repair Neuron Remodeling Gene Expression 3'-UTR-mediated MRNA Stabilization Positive Regulation Of Catenin Import Into Nucleus Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Protein Import Into Nucleus, Translocation Positive Regulation Of Cellular Biosynthetic Process MRNA Processing Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Aromatic Compound Catabolic Process Regulation Of MRNA 3'-end Processing
Tagcloud ?		bace1 bingo cdk2 clustering criterion cytoscape degs downloaded glioma gse31262 hierarchical kif23 kobas language limma log2fc mbp multtest myelination omnibus ontology package pheatmap plp1 plug software string webgestalt wee1	5l avian bicistronic bona closed compatible concomitantly explanation fide herpesvirus ie immediate ires leader manners marek mdv1 message micrornas mutagenesis neurovirulence pabp1 poly pool pp14 recruitment ribosome serotype virally
Tagcloud (Difference) ?		bace1 bingo cdk2 clustering criterion cytoscape degs downloaded glioma gse31262 hierarchical kif23 kobas language limma log2fc mbp multtest myelination omnibus ontology package pheatmap plp1 plug software string webgestalt wee1	5l avian bicistronic bona closed compatible concomitantly explanation fide herpesvirus ie immediate ires leader manners marek mdv1 message micrornas mutagenesis neurovirulence pabp1 poly pool pp14 recruitment ribosome serotype virally
Tagcloud (Intersection) ?