ELAVL1 and ANP32A

Number of citations of the paper that reports this interaction (PubMedID 11018049)
93

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		ELAVL1	ANP32A
Description		ELAV like RNA binding protein 1	acidic nuclear phosphoprotein 32 family member A
Image
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Cytosol Cytoplasmic Stress Granule Membrane Sarcoplasm Cytoplasmic Vesicle Postsynapse Glutamatergic Synapse Ribonucleoprotein Complex	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Perinuclear Region Of Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding Double-stranded RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Protein Kinase Binding MiRNA Binding MRNA 3'-UTR AU-rich Region Binding Protein Homodimerization Activity LncRNA Binding	RNA Binding Protein Binding Histone Binding
	Biological Process	LncRNA-mediated Post-transcriptional Gene Silencing Protein Import Into Nucleus Cell Population Proliferation Response To Glucose Positive Regulation Of Autophagy Post-transcriptional Gene Silencing Positive Regulation Of Superoxide Anion Generation Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Autophagosome Size MRNA Stabilization Protein Homooligomerization Negative Regulation Of MiRNA-mediated Gene Silencing MRNA Destabilization 3'-UTR-mediated MRNA Stabilization Regulation Of Stem Cell Population Maintenance	Nucleocytoplasmic Transport Intracellular Signal Transduction Regulation Of Apoptotic Process
Pathways		HuR (ELAVL1) binds and stabilizes mRNA	HuR (ELAVL1) binds and stabilizes mRNA
Drugs
Diseases
GWAS			Esophageal cancer ( 21642993)
Interacting Genes		44 interacting genes: AKT1 ANP32A ANP32B APOE C12orf75 CARM1 CEBPA CELF2 CHEK2 CTNNB1 ERG FAF2 GJB3 HNRNPK HOTAIR IL6 IL7R KPNA1 KPNB1 LINC00460 LINC00632 MIRLET7B MIRLET7I NEIL3 NOS3 PAIP2 PLAU PLAUR PRKCA PRKCD PRKCE PSEN2 PTBP2 PTGS2 RBFOX2 SDCBP SET SHANK3 SREK1 TNPO1 TNPO2 TRIM21 VCP VEGFA	30 interacting genes: ADAP1 APEX1 ATXN1 AXIN1 CHAF1A E4F1 ELAVL1 H2AC20 H2BC21 H3-4 H3C1 H3C15 H4C1 H4C16 HSPB3 KPNA1 KPNA5 KPNA6 LHX3 LINC00632 MAP1B NSFL1C PCBP1 PGR PPARG PTPRC SET TAF1A THRB XPO1
Entrez ID		1994	8125
HPRD ID		16025	09014
Ensembl ID		ENSG00000066044	ENSG00000140350
Uniprot IDs		Q15717	A0A384P5U2 P39687
PDB IDs		3HI9 4ED5 4EGL 4FXV 5SZW 6G2K 6GC5 6GD1 6GD2 6GD3	2JE0 2JE1 4XOS 6XZQ 8RMR 8RN0 8RNA 8RNB 8RNC
Enriched GO Terms of Interacting Partners?		Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Signal Transduction Negative Regulation Of Programmed Cell Death Enzyme Binding Regulation Of Primary Metabolic Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Nuclear Import Signal Receptor Activity Regulation Of Signal Transduction Regulation Of Platelet Activation Nuclear Localization Sequence Binding Regulation Of Macromolecule Metabolic Process Stress Granule Disassembly Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Endothelial Cell Migration Regulation Of Cell Communication Regulation Of Signaling Regulation Of Gene Expression Regulation Of Intracellular Signal Transduction Regulation Of Blood Coagulation Positive Regulation Of Catabolic Process Intracellular Signaling Cassette Regulation Of Fat Cell Differentiation Regulation Of Hemostasis Regulation Of Wound Healing Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Lipid Metabolic Process Regulation Of Cell Population Proliferation Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Multicellular Organismal Process Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Response To Oxidative Stress Positive Regulation Of Developmental Process Intracellular Signal Transduction Regulation Of Response To Wounding Urokinase Plasminogen Activator Signaling Pathway Positive Regulation Of Lipid Biosynthetic Process Negative Regulation Of Blood Coagulation Regulation Of Body Fluid Levels Negative Regulation Of Hemostasis Negative Regulation Of Coagulation Signal Transduction Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Cell Differentiation Diacylglycerol-dependent Serine/threonine Kinase Activity	Nucleosome Assembly Nucleosome Organization Structural Constituent Of Chromatin Nucleus Protein-DNA Complex Assembly Nucleosome Chromatin Remodeling DNA Binding Chromatin Organization Nuclear Transport Nucleocytoplasmic Transport NLS-dependent Protein Nuclear Import Complex Nucleoplasm Protein Heterodimerization Activity Nuclear Import Signal Receptor Activity Nuclear Localization Sequence Binding Negative Regulation Of Macromolecule Biosynthetic Process NLS-bearing Protein Import Into Nucleus Protein Localization To Organelle Negative Regulation Of Biosynthetic Process Protein Localization To Nucleus Negative Regulation Of RNA Metabolic Process Chromosome Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein-containing Complex Assembly Protein-containing Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Biosynthetic Process Protein Import Into Nucleus DNA Replication-dependent Chromatin Assembly Import Into Nucleus Telomere Organization Transcription Coactivator Binding Nuclear Receptor Activity Protein-containing Complex Organization Cellular Component Assembly Negative Regulation Of Metabolic Process Transcription By RNA Polymerase II Chromatin Binding Regulation Of Nucleobase-containing Compound Metabolic Process Establishment Of Localization In Cell Positive Regulation Of Transcription By RNA Polymerase II Chromosome, Telomeric Region Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin
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