ELAVL1 and HNRNPK

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid)

		ELAVL1	HNRNPK
Gene Name		ELAV like RNA binding protein 1	heterogeneous nuclear ribonucleoprotein K
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane	Nuclear Chromatin Podosome Nucleus Nucleoplasm Cytoplasm Focal Adhesion Membrane Cell Projection Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding RNA Binding Double-stranded RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding AU-rich Element Binding Protein Kinase Binding MRNA 3'-UTR AU-rich Region Binding Poly(A) RNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Single-stranded DNA Binding RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Multicellular Organismal Development Gene Expression Positive Regulation Of Translation MRNA Stabilization 3'-UTR-mediated MRNA Stabilization Regulation Of Stem Cell Maintenance	MRNA Splicing, Via Spliceosome Transcription, DNA-templated RNA Processing Signal Transduction RNA Splicing Gene Expression Regulation Of Low-density Lipoprotein Particle Clearance Viral Process Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Regulation of mRNA stability by proteins that bind AU-rich elements HuR stabilizes mRNA	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		35 interactors: ANP32A ANP32B APOE CARM1 CELF2 CHEK2 CTNNB1 ERG GJB3 HNRNPK HOTAIR IL7R KPNA1 KPNB1 MIRLET7B MIRLET7I NOS3 PAIP2 PLAU PLAUR PRKCA PRKCD PRKCE PSEN2 PTBP1 PTBP2 PTGS2 RBFOX2 SDCBP SET SREK1 TNPO1 TNPO2 VEGFA XIAP	107 interactors: ABI2 APBB1 AQP5 BTRC C6orf226 CBLB CCAR1 CCDC33 CDKN1A CEBPB CIRBP CNNM3 CSK CTNNBL1 DALRD3 DDX1 DDX17 DDX5 DHX9 DIDO1 DOCK2 EIF3F ELAVL1 FBXL18 FYN GFI1B GRAP2 GRB2 GZMA GZMK HCK HIST3H3 HMGB1 HNRNPA0 HNRNPD HNRNPL HNRNPLL ITK ITSN2 KHDRBS1 KHDRBS2 KHDRBS3 LYN MAPK10 MARK4 MATR3 NCK2 NEDD4 NPDC1 PABPC1 PCBP1 PCBP2 PCDHB14 PELI2 PIN1 PPP1R10 PRKCD PRMT1 PRPF31 PRPF40A PRR3 PTBP1 QKI RALY RASD1 RBFOX2 RBM10 RBM3 RBM4 RBM41 RBM42 RBM7 RBMX RBMY1A1 RBMY1F RNA18S5 RNA28S5 RTP5 SAFB SF1 SMAD3 SNRPA SORBS3 SPG7 SRC SREK1 SRRT SRSF3 SUMO1 SYNCRIP TBP TCERG1 TERF2IP TYK2 U2AF1 U2AF2 UBE2I VAV1 WBP4 WWOX YBX1 YTHDC1 YWHAQ ZFC3H1 ZNF385C ZNF792 ZNRF2P1
Entrez ID		1994	3190
HPRD ID		16025	02834
Ensembl ID		ENSG00000066044	ENSG00000165119
Uniprot IDs		B4DVB8 Q15717	B4DFF1 B4DUQ1 P61978 Q6IBN1
PDB IDs		3HI9 4ED5 4EGL 4FXV	1J5K 1KHM 1ZZI 1ZZJ 1ZZK
Enriched GO Terms of Interacting Partners?		Regulation Of Wound Healing Regulation Of Blood Coagulation Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Positive Regulation Of Transport Negative Regulation Of Wound Healing Apoptotic Process Regulation Of Protein Metabolic Process Programmed Cell Death Negative Regulation Of Cellular Protein Metabolic Process Cell Death Death Regulation Of Platelet Activation Regulation Of Metabolic Process Cell Communication Signal Transduction Negative Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Ion Transport Regulation Of Nitrogen Compound Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Receptor Activity Signaling Response To Abiotic Stimulus Blood Coagulation Negative Regulation Of Platelet Activation Hemostasis Regulation Of Epithelial Cell Migration Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cellular Response To Stimulus Regulation Of Apoptotic Process Regulation Of Cell Proliferation Response To External Stimulus Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Blood Vessel Endothelial Cell Migration Cellular Response To Organic Substance Regulation Of Cell Death Response To Wounding Blood Circulation Response To Cytokine Execution Phase Of Apoptosis Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Cell Death Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Epithelial Cell Migration Vasculature Development RNA Splicing Regulation Of Peptidyl-tyrosine Phosphorylation	RNA Processing MRNA Processing RNA Splicing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Gene Expression Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Posttranscriptional Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Stability Regulation Of RNA Stability Immune Response Positive Regulation Of Metabolic Process MRNA Stabilization Innate Immune Response Regulation Of Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Peptidyl-tyrosine Autophosphorylation Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Regulation Of RNA Metabolic Process Metabolic Process Regulation Of Translation Negative Regulation Of Biosynthetic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Immune System Process Positive Regulation Of Gene Expression Regulation Of Immune System Process Defense Response Fc Receptor Signaling Pathway Positive Regulation Of Signal Transduction T Cell Costimulation Immune Response-regulating Cell Surface Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		bace1 bingo cdk2 clustering criterion cytoscape degs downloaded glioma gse31262 hierarchical kif23 kobas language limma log2fc mbp multtest myelination omnibus ontology package pheatmap plp1 plug software string webgestalt wee1	associates boosted consequently cpg dnmt1 facilitated h3k9 h3k9me3 heterochromatin impairs insight instead intergenic lincrna link lncrnas methyltransferase noncoding notably p21 pluripotency prevents profiling promoters reprogramming rnas setdb1 somatic sustaining
Tagcloud (Difference) ?		bace1 bingo cdk2 clustering criterion cytoscape degs downloaded glioma gse31262 hierarchical kif23 kobas language limma log2fc mbp multtest myelination omnibus ontology package pheatmap plp1 plug software string webgestalt wee1	associates boosted consequently cpg dnmt1 facilitated h3k9 h3k9me3 heterochromatin impairs insight instead intergenic lincrna link lncrnas methyltransferase noncoding notably p21 pluripotency prevents profiling promoters reprogramming rnas setdb1 somatic sustaining
Tagcloud (Intersection) ?