RAB11FIP4 and ARF6

Number of citations of the paper that reports this interaction (PubMedID 16148947)
37

Data Source:
BioGRID (affinity chromatography technology, imaging technique, pull down)

		RAB11FIP4	ARF6
Description		RAB11 family interacting protein 4	ARF GTPase 6
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Endosome Golgi Apparatus Centrosome Spindle Cytoskeleton Membrane Endocytic Vesicle Midbody Cytoplasmic Vesicle Cleavage Furrow Perinuclear Region Of Cytoplasm Recycling Endosome Membrane	Ruffle Cytoplasm Endosome Early Endosome Golgi Apparatus Cytosol Plasma Membrane Focal Adhesion Cell Cortex Endosome Membrane Membrane Endocytic Vesicle Midbody Filopodium Membrane Early Endosome Membrane Cleavage Furrow Cell Projection Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Flemming Body Presynapse Postsynapse Glutamatergic Synapse
	Molecular Function	Calcium Ion Binding Protein Binding Small GTPase Binding Protein Homodimerization Activity Metal Ion Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Thioesterase Binding Signaling Adaptor Activity
	Biological Process	Neural Retina Development Endocytic Recycling Regulation Of Cytokinesis Positive Regulation Of G1 To G0 Transition	Mitotic Cytokinesis Liver Development Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Cell Adhesion Nervous System Development Regulation Of Neuron Projection Development Positive Regulation Of Neuron Projection Development Protein Transport Vesicle-mediated Transport Cell Differentiation Positive Regulation Of Actin Filament Polymerization Cortical Actin Cytoskeleton Organization Endocytic Recycling Protein Localization To Cell Surface Regulation Of Rac Protein Signal Transduction Protein Localization To Endosome Negative Regulation Of Receptor-mediated Endocytosis Synaptic Vesicle Endocytosis Positive Regulation Of Protein Secretion Cell Division Regulation Of Filopodium Assembly Positive Regulation Of Keratinocyte Migration Regulation Of Dendritic Spine Development Cellular Response To Diacyl Bacterial Lipopeptide Protein Localization To Plasma Membrane Establishment Of Epithelial Cell Polarity Ruffle Assembly Hepatocyte Apoptotic Process Maintenance Of Postsynaptic Density Structure Positive Regulation Of Focal Adhesion Disassembly Erythrocyte Apoptotic Process Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Mitotic Cytokinetic Process Protein Localization To Cleavage Furrow Regulation Of Presynapse Assembly Cellular Response To Nerve Growth Factor Stimulus Negative Regulation Of Protein Localization To Cell Surface Negative Regulation Of Dendrite Development
Pathways			TBC/RABGAPs Clathrin-mediated endocytosis MET receptor recycling
Drugs			5'-Guanosine-Diphosphate-Monothiophosphate Guanosine-5'-Diphosphate Myristic acid
Diseases
GWAS		Adventurousness ( 30643258) Apolipoprotein A1 levels ( 32203549) Brain morphology (MOSTest) ( 32665545) Facial attractiveness (male raters) ( 30946739) Heel bone mineral density ( 28869591 30598549) Hip circumference adjusted for BMI ( 34021172) Keratoconus ( 33649486) Myocardial infarction ( 33532862)	Erythema nodosum in inflammatory bowel disease ( 24487271) Ferritin levels ( 33491795)
Interacting Genes		9 interacting genes: ARF6 ECPAS GFI1B MAD2L2 PKNOX1 RAB11A RAB11FIP2 RAB11FIP3 RAB11FIP5	40 interacting genes: AGAP1 AP1B1 AP2B1 AP3B1 AP3D1 AP3S2 APP ARFIP2 ARHGAP10 ARRB1 ARRB2 ASAP1 ASAP2 ASAP3 ATP6V0C CAPN1 CHRM3 CLTC CYTH1 CYTH2 EXOC5 EZR FILNC1 HTR2A IKBKG ITSN1 MEOX2 MT2A PALS1 PIP5K1A PIP5K1C PLD1 RAB11A RAB11FIP3 RAB11FIP4 RAB11FIP5 SMAP1 SNCA SPAG9 ZNF709
Entrez ID		84440	382
HPRD ID		11466	02714
Ensembl ID		ENSG00000131242	ENSG00000165527
Uniprot IDs		Q86YS3	P62330
PDB IDs			1E0S 2A5D 2A5F 2A5G 2BAO 2BAU 2J5X 2W83 3LVQ 3LVR 3N5C 3PCR 4FME 4KAX 6BBP 6BBQ 6PAU 7RK3 7XRD
Enriched GO Terms of Interacting Partners?		Protein Localization To Cleavage Furrow Recycling Endosome Membrane Positive Regulation Of Mitotic Cytokinetic Process Positive Regulation Of Mitotic Cytokinesis Regulation Of Mitotic Cytokinesis Recycling Endosome Positive Regulation Of Cilium Assembly Endosome Vesicle Docking Involved In Exocytosis Positive Regulation Of Cytokinesis Regulation Of Early Endosome To Recycling Endosome Transport Negative Regulation Of Adiponectin Secretion Protein Localization To Plasma Membrane Early Endosome To Recycling Endosome Transport Cleavage Furrow Vesicle Docking Protein Localization To Cilium Regulation Of Cell Projection Assembly Mitotic Cytokinesis Protein Localization To Cell Periphery Positive Regulation Of Protein Localization To Plasma Membrane Endocytic Vesicle Positive Regulation Of Protein Localization To Cell Periphery Protein Transport Endocytic Recycling Organelle Localization By Membrane Tethering Regulation Of Cytokinesis Small GTPase Binding Positive Regulation Of Protein Localization To Membrane Membrane Docking Positive Regulation Of Cell Division Cytoskeleton-dependent Cytokinesis Establishment Of Cell Polarity Protein Localization To Membrane Regulation Of Protein Localization To Centrosome Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Organelle Assembly Regulation Of Cilium Assembly Establishment Of Protein Localization Regulation Of Cell Cycle Process Positive Regulation Of Cell Projection Organization Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Regulation Of Protein Localization To Plasma Membrane Vesicle-mediated Transport To The Plasma Membrane Regulation Of Endocytic Recycling Regulation Of Protein Transport Establishment Of Localization In Cell Regulation Of Protein Localization To Cell Periphery Regulation Of Protein Localization Establishment Or Maintenance Of Cell Polarity	Vesicle-mediated Transport Cytoplasmic Vesicle Intracellular Protein Localization Membrane Coat Establishment Of Localization In Cell Trans-Golgi Network Membrane Receptor-mediated Endocytosis Endocytosis Receptor Internalization Clathrin-coated Pit Protein Transport Melanosome Assembly Vesicle-mediated Transport In Synapse Regulation Of Vesicle-mediated Transport Cellular Localization Cytoplasmic Vesicle Membrane Organelle Localization Establishment Of Vesicle Localization Platelet Dense Granule Organization Import Into Cell Clathrin-coated Vesicle Cargo Loading, AP-3-mediated Golgi Membrane Establishment Of Protein Localization Vesicle Localization Clathrin-dependent Endocytosis Cellular Component Assembly Endocytic Vesicle Membrane Synaptic Vesicle Transport Melanosome Organization AP-3 Adaptor Complex Pigment Granule Organization Synaptic Vesicle Endocytosis Clathrin Adaptor Complex Positive Regulation Of Endocytosis GTPase Activator Activity Presynaptic Endocytosis Plasma Membrane Lysosomal Membrane Angiotensin Receptor Binding Golgi Apparatus Establishment Of Organelle Localization Secretion Post-Golgi Vesicle-mediated Transport Secretion By Cell Localization Within Membrane Intracellular Transport Regulation Of Cellular Component Organization Protein Localization To Plasma Membrane Anterograde Synaptic Vesicle Transport Focal Adhesion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?