ITGAD and ICAM3

Number of citations of the paper that reports this interaction (PMID 8777714)
26

Data Source:
HPRD (in vitro)

		ITGAD	ICAM3
Gene Name		integrin, alpha D	intercellular adhesion molecule 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integrin Complex Cell Surface	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Metal Ion Binding	Receptor Binding Integrin Binding Protein Binding
	Biological Process	Immune Response Integrin-mediated Signaling Pathway Extracellular Matrix Organization Heterotypic Cell-cell Adhesion Activated T Cell Proliferation	Cell Adhesion Single Organismal Cell-cell Adhesion Extracellular Matrix Organization Regulation Of Immune Response
Pathways		Integrin cell surface interactions	Integrin cell surface interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS			Crohn's disease ( 21102463)
Protein-Protein Interactions		4 interactors: ICAM3 ITGB2 SHARPIN VCAM1	10 interactors: APP CD209 CLEC4M EZR ITGAD ITGAL ITGB2 MSN PRKCQ ZBTB16
Entrez ID		3681	3385
HPRD ID		11785	00889
Ensembl ID		ENSG00000156886	ENSG00000076662
Uniprot IDs		Q13349 Q59H14	P32942
PDB IDs			1T0P
Enriched GO Terms of Interacting Partners?		Cellular Extravasation Extracellular Matrix Organization Extracellular Structure Organization Single Organismal Cell-cell Adhesion Regulation Of Immune Response Cell Chemotaxis Cell-matrix Adhesion Cell-substrate Adhesion Regulation Of CD40 Signaling Pathway Protein Linear Polyubiquitination Cell Adhesion Leukocyte Migration Regulation Of Immune System Process Membrane To Membrane Docking Leukocyte Cell-cell Adhesion Aging Chorio-allantoic Fusion Lymphocyte Activation Inflammatory Response Leukocyte Migration Involved In Inflammatory Response Chronic Inflammatory Response Leukocyte Tethering Or Rolling Leukocyte Activation Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Chemotaxis Heterotypic Cell-cell Adhesion Labyrinthine Layer Morphogenesis Activated T Cell Proliferation Embryonic Morphogenesis Cell Activation Embryonic Placenta Morphogenesis Apoptotic Nuclear Changes Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Endodermal Cell Differentiation Response To Nicotine Innate Immune Response Cellular Response To Vascular Endothelial Growth Factor Stimulus Cell Migration Keratinization Neutrophil Chemotaxis Neutrophil Migration Response To Zinc Ion Cell Motility Positive Regulation Of Immune System Process Receptor Clustering Granulocyte Chemotaxis Regulation Of Nitric Oxide Biosynthetic Process Endoderm Formation	Leukocyte Cell-cell Adhesion Single Organismal Cell-cell Adhesion Cell Adhesion Immune System Process Activated T Cell Proliferation Immune Response Peptide Antigen Transport Membrane To Membrane Docking T Cell Proliferation Virion Attachment To Host Cell Locomotion Cell Activation Regulation Of T Cell Activation Regulation Of Immune System Process Defense Response Adhesion Of Symbiont To Host Innate Immune Response Movement Of Cell Or Subcellular Component Cellular Localization Extracellular Matrix Organization Regulation Of Cell-cell Adhesion Lymphocyte Proliferation Extracellular Structure Organization Mononuclear Cell Proliferation Integrin-mediated Signaling Pathway Regulation Of Lymphocyte Activation Leukocyte Proliferation Cell Recognition Blood Coagulation Hemostasis Regulation Of T Cell Proliferation Regulation Of Cell Activation Heterotypic Cell-cell Adhesion Modulation By Virus Of Host Morphology Or Physiology Viral Genome Replication Intracellular Transport Of Virus Establishment Of Endothelial Barrier Regulation Of Body Fluid Levels Chemotaxis Positive Regulation Of T Cell Activation Wound Healing Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Cell Adhesion Leukocyte Migration Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Endocytosis Positive Regulation Of Cell-cell Adhesion Response To Wounding Endothelial Cell Development T Cell Aggregation
Tagcloud ?			br ccl20 ccl3 ccl4 csf2 csf3 cxcl1 cxcl12 discordances extremities figf grew igfbp1 iib il1alpha il1beta il6 il8 lymphatic matrigel mmp1 mmp13 mmp9 mts6 plaur plgf tnfrsf18 vegfa vegfc
Tagcloud (Difference) ?			br ccl20 ccl3 ccl4 csf2 csf3 cxcl1 cxcl12 discordances extremities figf grew igfbp1 iib il1alpha il1beta il6 il8 lymphatic matrigel mmp1 mmp13 mmp9 mts6 plaur plgf tnfrsf18 vegfa vegfc
Tagcloud (Intersection) ?