ITGAD and SHARPIN

Number of citations of the paper that reports this interaction (PMID 24210817)
0

Data Source:
BioGRID (unspecified method)

		ITGAD	SHARPIN
Gene Name		integrin, alpha D	SHANK-associated RH domain interactor
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integrin Complex Cell Surface	Nucleus Nucleoplasm Cytoplasm Cytosol Postsynaptic Density Cell Junction Dendrite LUBAC Complex
	Molecular Function	Metal Ion Binding	Protein Binding Zinc Ion Binding Polyubiquitin Binding Protein Complex Binding Identical Protein Binding
	Biological Process	Immune Response Integrin-mediated Signaling Pathway Extracellular Matrix Organization Heterotypic Cell-cell Adhesion Activated T Cell Proliferation	Mitochondrion Organization Brain Development Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Apoptotic Nuclear Changes Keratinization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Inflammatory Response Protein Homooligomerization Protein Linear Polyubiquitination Regulation Of CD40 Signaling Pathway
Pathways		Integrin cell surface interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ICAM3 ITGB2 SHARPIN VCAM1	10 interactors: ITGA1 ITGA2 ITGAD ITGAL ITGAM SHANK1 SHANK2 TXN2 UBC UBE2D3
Entrez ID		3681	81858
HPRD ID		11785	15463
Ensembl ID		ENSG00000156886	ENSG00000179526
Uniprot IDs		Q13349 Q59H14	Q6PJD5 Q9H0F6
PDB IDs			4EMO
Enriched GO Terms of Interacting Partners?		Cellular Extravasation Extracellular Matrix Organization Extracellular Structure Organization Single Organismal Cell-cell Adhesion Regulation Of Immune Response Cell Chemotaxis Cell-matrix Adhesion Cell-substrate Adhesion Regulation Of CD40 Signaling Pathway Protein Linear Polyubiquitination Cell Adhesion Leukocyte Migration Regulation Of Immune System Process Membrane To Membrane Docking Leukocyte Cell-cell Adhesion Aging Chorio-allantoic Fusion Lymphocyte Activation Inflammatory Response Leukocyte Migration Involved In Inflammatory Response Chronic Inflammatory Response Leukocyte Tethering Or Rolling Leukocyte Activation Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Chemotaxis Heterotypic Cell-cell Adhesion Labyrinthine Layer Morphogenesis Activated T Cell Proliferation Embryonic Morphogenesis Cell Activation Embryonic Placenta Morphogenesis Apoptotic Nuclear Changes Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Endodermal Cell Differentiation Response To Nicotine Innate Immune Response Cellular Response To Vascular Endothelial Growth Factor Stimulus Cell Migration Keratinization Neutrophil Chemotaxis Neutrophil Migration Response To Zinc Ion Cell Motility Positive Regulation Of Immune System Process Receptor Clustering Granulocyte Chemotaxis Regulation Of Nitric Oxide Biosynthetic Process Endoderm Formation	Integrin-mediated Signaling Pathway Activated T Cell Proliferation Extracellular Matrix Organization Extracellular Structure Organization T Cell Proliferation Toll-like Receptor 4 Signaling Pathway Response To Hypoxia Response To Wounding Toll-like Receptor Signaling Pathway Lymphocyte Proliferation Mononuclear Cell Proliferation Leukocyte Proliferation Positive Regulation Of Immune System Process Vocalization Behavior Blood Coagulation Pattern Recognition Receptor Signaling Pathway Hemostasis Innate Immune Response-activating Signal Transduction Cell Communication Activation Of Innate Immune Response Cell-matrix Adhesion Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Innate Immune Response Cell Surface Receptor Signaling Pathway Cell Adhesion Cellular Extravasation Regulation Of Body Fluid Levels Positive Regulation Of Phosphatase Activity Wound Healing Cell-substrate Adhesion Immune System Process Immune Response Regulation Of Immune System Process Leukocyte Migration Response To Stress Regulation Of Innate Immune Response Social Behavior Cell Proliferation Negative Regulation Of Type I Interferon Production Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Dephosphorylation Negative Regulation Of ERBB Signaling Pathway T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Neutrophil Chemotaxis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Neutrophil Migration Regulation Of DNA-templated Transcription In Response To Stress
Tagcloud ?			1l chain composed conjugation consists deeply elusive fluorescein fret fungal gliotoxin hoil hoip hts ibr linear lubac malignancy metabolite modulator nemo ring searched selectively tb3 termini though throughput ubiquitin
Tagcloud (Difference) ?			1l chain composed conjugation consists deeply elusive fluorescein fret fungal gliotoxin hoil hoip hts ibr linear lubac malignancy metabolite modulator nemo ring searched selectively tb3 termini though throughput ubiquitin
Tagcloud (Intersection) ?