ITGAD and VCAM1

Number of citations of the paper that reports this interaction (PMID 10438935)
13

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		ITGAD	VCAM1
Gene Name		integrin, alpha D	vascular cell adhesion molecule 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integrin Complex Cell Surface	Podosome Extracellular Space Early Endosome Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Microvillus External Side Of Plasma Membrane Cell Surface Integral Component Of Membrane Filopodium Sarcolemma Apical Part Of Cell Extracellular Vesicular Exosome Alpha9-beta1 Integrin-vascular Cell Adhesion Molecule-1 Complex
	Molecular Function	Metal Ion Binding	Integrin Binding Primary Amine Oxidase Activity Cell Adhesion Molecule Binding
	Biological Process	Immune Response Integrin-mediated Signaling Pathway Extracellular Matrix Organization Heterotypic Cell-cell Adhesion Activated T Cell Proliferation	Response To Hypoxia Acute Inflammatory Response Chronic Inflammatory Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-matrix Adhesion Heart Development Aging Response To Nutrient Amine Metabolic Process Response To Zinc Ion Response To Ionizing Radiation Viral Process Cytokine-mediated Signaling Pathway Membrane To Membrane Docking B Cell Differentiation Extracellular Matrix Organization Response To Lipopolysaccharide Response To Nicotine Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of T Cell Proliferation Response To Ethanol Regulation Of Immune Response Leukocyte Tethering Or Rolling Oxidation-reduction Process Cell Chemotaxis Interferon-gamma-mediated Signaling Pathway Chorio-allantoic Fusion Cellular Response To Glucose Stimulus Cellular Response To Tumor Necrosis Factor
Pathways		Integrin cell surface interactions	Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system Integrin cell surface interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs			Carvedilol
Diseases
GWAS			Multiple sclerosis ( 21833088)
Protein-Protein Interactions		4 interactors: ICAM3 ITGB2 SHARPIN VCAM1	10 interactors: CCL17 CCL22 CTSG ELANE EZR IL13 ITGAD ITGB1 ITGB7 MSN
Entrez ID		3681	7412
HPRD ID		11785	01888
Ensembl ID		ENSG00000156886	ENSG00000162692
Uniprot IDs		Q13349 Q59H14	P19320
PDB IDs			1IJ9 1VCA 1VSC
Enriched GO Terms of Interacting Partners?		Cellular Extravasation Extracellular Matrix Organization Extracellular Structure Organization Single Organismal Cell-cell Adhesion Regulation Of Immune Response Cell Chemotaxis Cell-matrix Adhesion Cell-substrate Adhesion Regulation Of CD40 Signaling Pathway Protein Linear Polyubiquitination Cell Adhesion Leukocyte Migration Regulation Of Immune System Process Membrane To Membrane Docking Leukocyte Cell-cell Adhesion Aging Chorio-allantoic Fusion Lymphocyte Activation Inflammatory Response Leukocyte Migration Involved In Inflammatory Response Chronic Inflammatory Response Leukocyte Tethering Or Rolling Leukocyte Activation Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Chemotaxis Heterotypic Cell-cell Adhesion Labyrinthine Layer Morphogenesis Activated T Cell Proliferation Embryonic Morphogenesis Cell Activation Embryonic Placenta Morphogenesis Apoptotic Nuclear Changes Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Endodermal Cell Differentiation Response To Nicotine Innate Immune Response Cellular Response To Vascular Endothelial Growth Factor Stimulus Cell Migration Keratinization Neutrophil Chemotaxis Neutrophil Migration Response To Zinc Ion Cell Motility Positive Regulation Of Immune System Process Receptor Clustering Granulocyte Chemotaxis Regulation Of Nitric Oxide Biosynthetic Process Endoderm Formation	Immune System Process Movement Of Cell Or Subcellular Component Response To External Stimulus Heterotypic Cell-cell Adhesion Leukocyte Cell-cell Adhesion Locomotion Response To Other Organism Response To Biotic Stimulus Extracellular Matrix Organization Extracellular Structure Organization Cell Migration Cell Motility Single Organismal Cell-cell Adhesion Membrane To Membrane Docking Leukocyte Migration Killing By Host Of Symbiont Cells Immune Response Regulation Of Immune System Process Defense Response Integrin-mediated Signaling Pathway Leukocyte Tethering Or Rolling Inflammatory Response Neutrophil Mediated Immunity Killing Of Cells Of Other Organism Negative Regulation Of Growth Of Symbiont In Host Defense Response To Fungus Cell Adhesion Establishment Of Endothelial Barrier Cellular Extravasation Chemotaxis Interaction With Symbiont Leukocyte Mediated Cytotoxicity Response To Fungus Viral Entry Into Host Cell Entry Into Host Cell Response To Virus Endothelial Cell Development Response To Lipopolysaccharide Positive Regulation Of Smooth Muscle Cell Proliferation Response To Lipid Response To Molecule Of Bacterial Origin Regulation Of Immune Response Cellular Response To Mechanical Stimulus Positive Regulation Of Connective Tissue Growth Factor Production Positive Regulation Of Lung Goblet Cell Differentiation Negative Regulation Of Lung Ciliated Cell Differentiation Positive Regulation Of Pancreatic Stellate Cell Proliferation Positive Regulation Of Tyrosine Phosphorylation Of Stat6 Protein Endothelial Cell Differentiation Response To Stimulus
Tagcloud ?			accessory cd4 delayed determinant dr foreign genital hpvs hypersensitivity icam1 immuno keratinocytes langerhans lymphocytes monitored mount nonregressing papillomavirus predominated rank regressing regression responsiveness selectin stroma sum wart warts wilcoxon
Tagcloud (Difference) ?			accessory cd4 delayed determinant dr foreign genital hpvs hypersensitivity icam1 immuno keratinocytes langerhans lymphocytes monitored mount nonregressing papillomavirus predominated rank regressing regression responsiveness selectin stroma sum wart warts wilcoxon
Tagcloud (Intersection) ?