ITGAD

Description		integrin subunit alpha D
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integrin Complex Cell Surface Membrane
	Molecular Function	Signaling Receptor Activity Metal Ion Binding
	Biological Process	Immune Response Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Heterotypic Cell-cell Adhesion Cell-cell Adhesion
Pathways		Integrin cell surface interactions
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 34059833) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 27863252) Platelet count ( 32888494) Plateletcrit ( 32888494) Red cell distribution width ( 27863252 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		4 interacting genes: ICAM3 ITGB2 SHARPIN VCAM1
Entrez ID		3681
HPRD ID		11785
Ensembl ID		ENSG00000156886
Uniprot IDs		Q13349 Q59H14
PDB IDs
Enriched GO Terms of Interacting Partners?		Integrin Binding Cell Adhesion Mediated By Integrin Heterotypic Cell-cell Adhesion Leukocyte Cell-cell Adhesion Cell-cell Adhesion Phagocytosis Cell-matrix Adhesion Cell Adhesion Molecule Binding Alpha9-beta1 Integrin-vascular Cell Adhesion Molecule-1 Complex Cardiac Neuron Differentiation Cell Adhesion Integrin AlphaM-beta2 Complex Integrin AlphaX-beta2 Complex Cell-substrate Adhesion Integrin AlphaL-beta2 Complex Peripheral Nervous System Neuron Differentiation ICAM-3 Receptor Activity Positive Regulation Of Neutrophil Degranulation Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell Chemotaxis Negative Regulation Of Dopamine Metabolic Process LUBAC Complex Negative Regulation Of Catecholamine Metabolic Process Membrane To Membrane Docking Regulation Of Neutrophil Degranulation Positive Regulation Of Leukocyte Cell-cell Adhesion Primary Methylamine Oxidase Activity Cell-cell Adhesion Mediated By Integrin Apoptotic Nuclear Changes Protein Linear Polyubiquitination Regulation Of CD40 Signaling Pathway Defense Response Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Chemotaxis Positive Regulation Of Cell-cell Adhesion Chronic Inflammatory Response External Side Of Plasma Membrane Locomotion Complement Component C3b Binding Cell Adhesion Mediator Activity Regulation Of Leukocyte Cell-cell Adhesion Endocytosis Regulation Of Dopamine Metabolic Process Positive Regulation Of Cell Adhesion Regulation Of Superoxide Anion Generation Positive Regulation Of Superoxide Anion Generation Leukocyte Migration Involved In Inflammatory Response Cellular Extravasation Innervation Leukocyte Tethering Or Rolling
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