IRAK1 and IRF7

  • Number of citations of the paper that reports this interaction (PMID 15767370)
  • 87
  • Data Source:
  • BioGRID (affinity chromatography technology, fluorescent resonance energy transfer, enzymatic study)
  • HPRD (in vivo)

IRAK1

IRF7

Gene Name interleukin-1 receptor-associated kinase 1 interferon regulatory factor 7
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Systemic lupus erythematosus and Systemic sclerosis ( 23740937)
Protein-Protein Interactions 49 interactors: AKT1 BCL10 BTK CCDC47 FADD HIST3H3 HRAS HSP90AA1 IKBKG IL1RAP IRAK1BP1 IRAK2 IRAK3 IRAK4 IRF4 IRF7 ITGAM JUN MAP3K7 MAPK14 MAPK8 MBP MYD88 NLRP12 NTRK3 PELI1 PELI2 PELI3 PPP3CB PRKCI PRKCZ RIPK2 SIGIRR SQSTM1 STAT3 SUMO1 TAB2 TICAM2 TIFA TIRAP TLR2 TLR4 TMEM173 TOLLIP TRAF4 TRAF6 TRIM32 UNC93B1 YTHDC2 25 interactors: ACADS AIP ARAF CCDC47 CREBBP EP300 GCLM INSR IRAK1 IRF3 KAT2A KAT2B LTN1 MAVS MYD88 PALD1 PIAS4 TBK1 TICAM1 TICAM2 TLK2 TP53 TRAF6 TRIM28 TRMT61B
Entrez ID 3654 3665
HPRD ID 02235 05441
Ensembl ID ENSG00000184216 ENSG00000185507
Uniprot IDs D3YTB5 P51617 M9RSF4 Q92985
PDB IDs 2O61
Enriched GO Terms of Interacting Partners?
Tagcloud ?
auc  autoimmunity  cancerous  clinicopathological  curve  curves  distinguish  embedded  fixed  formalin  herein  lung  lymph  metastasis  microarrays  node  nsclc  operating  paraffin  receiver  roc  sclc  spearman  stream  tlr  tnm  toll  unclarified  valuable 
abolished  activator  amlexanox  aortic  augment  augmentation  augmented  end  endothelial  epsilon  gamma  ifn  ikappab  ikk  inducible  interferon  jak  janus  murine  nitric  oxide  poly  production  stat  synthase  tank  tbk  transducer 
Tagcloud (Difference) ?
auc  autoimmunity  cancerous  clinicopathological  curve  curves  distinguish  embedded  fixed  formalin  herein  lung  lymph  metastasis  microarrays  node  nsclc  operating  paraffin  receiver  roc  sclc  spearman  stream  tlr  tnm  toll  unclarified  valuable 
abolished  activator  amlexanox  aortic  augment  augmentation  augmented  end  endothelial  epsilon  gamma  ifn  ikappab  ikk  inducible  interferon  jak  janus  murine  nitric  oxide  poly  production  stat  synthase  tank  tbk  transducer 
Tagcloud (Intersection) ?