IRAK1 and IRAK2

  • Number of citations of the paper that reports this interaction (PMID 10383454)
  • 63
  • Data Source:
  • HPRD (in vivo)

IRAK1

IRAK2

Gene Name interleukin-1 receptor-associated kinase 1 interleukin-1 receptor-associated kinase 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 49 interactors: AKT1 BCL10 BTK CCDC47 FADD HIST3H3 HRAS HSP90AA1 IKBKG IL1RAP IRAK1BP1 IRAK2 IRAK3 IRAK4 IRF4 IRF7 ITGAM JUN MAP3K7 MAPK14 MAPK8 MBP MYD88 NLRP12 NTRK3 PELI1 PELI2 PELI3 PPP3CB PRKCI PRKCZ RIPK2 SIGIRR SQSTM1 STAT3 SUMO1 TAB2 TICAM2 TIFA TIRAP TLR2 TLR4 TMEM173 TOLLIP TRAF4 TRAF6 TRIM32 UNC93B1 YTHDC2 20 interactors: ARAF HRAS IL1R1 IRAK1 IRAK3 MYD88 PELI1 PELI2 PELI3 SARM1 SMAD2 SMURF1 STT3A TARDBP TICAM2 TIRAP TLR4 TOLLIP TRAF6 ZC3H12A
Entrez ID 3654 3656
HPRD ID 02235 04491
Ensembl ID ENSG00000184216 ENSG00000134070
Uniprot IDs D3YTB5 P51617 O43187
PDB IDs 3MOP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
auc  autoimmunity  cancerous  clinicopathological  curve  curves  distinguish  embedded  fixed  formalin  herein  lung  lymph  metastasis  microarrays  node  nsclc  operating  paraffin  receiver  roc  sclc  spearman  stream  tlr  tnm  toll  unclarified  valuable 
adapter  bmdm  bmdms  catalytically  corrected  d359a  e525a  hardly  il10  il6  irak1  knock  limiting  modest  myd88  pdcs  plasmacytoid  secretion  sustain  tlr  tlr4  tlr7  tlr9  tnfa  tnfr  toll  traf6  trif 
Tagcloud (Difference) ?
auc  autoimmunity  cancerous  clinicopathological  curve  curves  distinguish  embedded  fixed  formalin  herein  lung  lymph  metastasis  microarrays  node  nsclc  operating  paraffin  receiver  roc  sclc  spearman  stream  tnm  unclarified  valuable 
adapter  bmdm  bmdms  catalytically  corrected  d359a  e525a  hardly  il10  il6  knock  limiting  modest  myd88  pdcs  plasmacytoid  secretion  sustain  tlr4  tlr7  tlr9  tnfa  tnfr  traf6  trif 
Tagcloud (Intersection) ?
irak1  tlr  toll