IRAK1 and TLR4

  • Number of citations of the paper that reports this interaction (PMID 9625770)
  • 86
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

IRAK1

TLR4

Gene Name interleukin-1 receptor-associated kinase 1 toll-like receptor 4
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 49 interactors: AKT1 BCL10 BTK CCDC47 FADD HIST3H3 HRAS HSP90AA1 IKBKG IL1RAP IRAK1BP1 IRAK2 IRAK3 IRAK4 IRF4 IRF7 ITGAM JUN MAP3K7 MAPK14 MAPK8 MBP MYD88 NLRP12 NTRK3 PELI1 PELI2 PELI3 PPP3CB PRKCI PRKCZ RIPK2 SIGIRR SQSTM1 STAT3 SUMO1 TAB2 TICAM2 TIFA TIRAP TLR2 TLR4 TMEM173 TOLLIP TRAF4 TRAF6 TRIM32 UNC93B1 YTHDC2 24 interactors: BCL10 BTK CD14 CNPY4 DEFB4A HMGB1 HSP90B1 IRAK1 IRAK2 LY96 MAPK8IP3 MYD88 NOX4 RIPK2 RNF216 SERTAD1 SIGIRR SMAD3 SYK TICAM2 TIRAP TLR1 TLR5 TOLLIP
Entrez ID 3654 7099
HPRD ID 02235 04325
Ensembl ID ENSG00000184216 ENSG00000136869
Uniprot IDs D3YTB5 P51617 O00206
PDB IDs 2Z62 2Z63 2Z65 2Z66 3FXI 3UL7 3UL8 3UL9 3ULA 4G8A
Enriched GO Terms of Interacting Partners?
Tagcloud ?
auc  autoimmunity  cancerous  clinicopathological  curve  curves  distinguish  embedded  fixed  formalin  herein  lung  lymph  metastasis  microarrays  node  nsclc  operating  paraffin  receiver  roc  sclc  spearman  stream  tlr  tnm  toll  unclarified  valuable 
bed  cd14  constitutively  fibroblast  immunoassay  immunocytochemistry  lamina  lipopolysaccharide  lps  md  measuring  microorganisms  nucleus  p65  polyp  propria  quantified  respond  responsiveness  scar  strategic  supernatant  tlr1  tlr9  tlrs  toll  vff  vffs  vocal 
Tagcloud (Difference) ?
auc  autoimmunity  cancerous  clinicopathological  curve  curves  distinguish  embedded  fixed  formalin  herein  lung  lymph  metastasis  microarrays  node  nsclc  operating  paraffin  receiver  roc  sclc  spearman  stream  tlr  tnm  unclarified  valuable 
bed  cd14  constitutively  fibroblast  immunoassay  immunocytochemistry  lamina  lipopolysaccharide  lps  md  measuring  microorganisms  nucleus  p65  polyp  propria  quantified  respond  responsiveness  scar  strategic  supernatant  tlr1  tlr9  tlrs  vff  vffs  vocal 
Tagcloud (Intersection) ?
toll