INPP1 and NECAB2

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		INPP1	NECAB2
Gene Name		inositol polyphosphate-1-phosphatase	N-terminal EF-hand calcium binding protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Cytoplasm
	Molecular Function	Inositol-1,4-bisphosphate 1-phosphatase Activity Metal Ion Binding Inositol-1,3,4-trisphosphate 1-phosphatase Activity	Calcium Ion Binding Protein Binding
	Biological Process	Phosphate-containing Compound Metabolic Process Signal Transduction Dephosphorylation Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Phosphatidylinositol Phosphorylation
Pathways		Synthesis of IP2, IP, and Ins in the cytosol Inositol phosphate metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: BRCA1 C9orf16 DYNLL1 LDOC1 LIG1 MEOX2 NDC80 NECAB2 NR1D1 SYCE3 USHBP1	53 interactors: AIMP2 BEX2 BYSL C1orf109 CAPN3 CARD9 CCDC146 CCDC151 CCDC153 CCDC33 CCNK CENPO DAXX DFFA DGCR6 DGCR6L EHHADH EIF4E2 FAM161A FXR2 GCC1 GTPBP10 HAUS1 INPP1 ISCU KANSL1 KDM1A KIFC3 KLC3 KLC4 KPNA2 LENG1 LNX1 MED14 MRPS27 NEK6 NGFRAP1 NIP7 NOC4L PRKAA2 PSMA1 RCOR3 RIC8A RUNX1T1 SDCBP SH2D4A SSC5D TEX11 TTC25 TTR USP7 VTA1 WDYHV1
Entrez ID		3628	54550
HPRD ID		00923	13263
Ensembl ID		ENSG00000151689	ENSG00000103154
Uniprot IDs		P49441 Q6IBG4	Q7Z6G3
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Process Cell Cycle Chromosome Segregation DNA Recombination Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Bile Acid Biosynthetic Process Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cell Division Circadian Temperature Homeostasis Positive Regulation Of Histone H3-K9 Acetylation Regulation Of Type B Pancreatic Cell Proliferation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Regulation Of Lipid Biosynthetic Process Double-strand Break Repair Otolith Morphogenesis Attachment Of Mitotic Spindle Microtubules To Kinetochore Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Negative Regulation Of Receptor Biosynthetic Process Lagging Strand Elongation Somite Specification Intrinsic Apoptotic Signaling Pathway Mitotic Cell Cycle Microtubule-based Process Nucleobase-containing Compound Metabolic Process Intracellular Receptor Signaling Pathway Otolith Development Dosage Compensation By Inactivation Of X Chromosome Protein K6-linked Ubiquitination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter DNA Ligation Involved In DNA Repair Regulation Of Histone H3-K9 Acetylation Organelle Organization Cellular Nitrogen Compound Metabolic Process Attachment Of Spindle Microtubules To Kinetochore DNA Replication Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation DNA Ligation Regulation Of Histone H4 Acetylation Negative Regulation Of Fatty Acid Biosynthetic Process	Organelle Organization Cell Cycle Regulation Of Apoptotic Process Apoptotic Process Ribosome Biogenesis Regulation Of Cell Death Programmed Cell Death Regulation Of Protein Metabolic Process Cell Cycle Process Cellular Component Assembly Cell Death Death Chromatin Modification Regulation Of Cellular Protein Metabolic Process Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of SSU-rRNA Positive Regulation Of JNK Cascade Organelle Assembly Cell-cell Adhesion Involved In Gastrulation Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Apoptotic DNA Fragmentation Nitrogen Fixation Autolysis Chromatin Organization Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
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