INPP1 and C9orf16

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		INPP1	C9orf16
Gene Name		inositol polyphosphate-1-phosphatase	chromosome 9 open reading frame 16
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Cellular_component
	Molecular Function	Inositol-1,4-bisphosphate 1-phosphatase Activity Metal Ion Binding Inositol-1,3,4-trisphosphate 1-phosphatase Activity	Molecular_function
	Biological Process	Phosphate-containing Compound Metabolic Process Signal Transduction Dephosphorylation Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Phosphatidylinositol Phosphorylation	Biological_process
Pathways		Synthesis of IP2, IP, and Ins in the cytosol Inositol phosphate metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: BRCA1 C9orf16 DYNLL1 LDOC1 LIG1 MEOX2 NDC80 NECAB2 NR1D1 SYCE3 USHBP1	7 interactors: ATP6V1D ATP6V1E2 CEP290 IKBIP INPP1 KRT20 THAP11
Entrez ID		3628	79095
HPRD ID		00923	12946
Ensembl ID		ENSG00000151689	ENSG00000171159
Uniprot IDs		P49441 Q6IBG4	Q9BUW7
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Process Cell Cycle Chromosome Segregation DNA Recombination Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Bile Acid Biosynthetic Process Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cell Division Circadian Temperature Homeostasis Positive Regulation Of Histone H3-K9 Acetylation Regulation Of Type B Pancreatic Cell Proliferation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Regulation Of Lipid Biosynthetic Process Double-strand Break Repair Otolith Morphogenesis Attachment Of Mitotic Spindle Microtubules To Kinetochore Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Negative Regulation Of Receptor Biosynthetic Process Lagging Strand Elongation Somite Specification Intrinsic Apoptotic Signaling Pathway Mitotic Cell Cycle Microtubule-based Process Nucleobase-containing Compound Metabolic Process Intracellular Receptor Signaling Pathway Otolith Development Dosage Compensation By Inactivation Of X Chromosome Protein K6-linked Ubiquitination Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Gluconeogenesis By Regulation Of Transcription From RNA Polymerase II Promoter DNA Ligation Involved In DNA Repair Regulation Of Histone H3-K9 Acetylation Organelle Organization Cellular Nitrogen Compound Metabolic Process Attachment Of Spindle Microtubules To Kinetochore DNA Replication Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation DNA Ligation Regulation Of Histone H4 Acetylation Negative Regulation Of Fatty Acid Biosynthetic Process	Transferrin Transport Phagosome Maturation Iron Ion Transport Cellular Iron Ion Homeostasis Interaction With Host Iron Ion Homeostasis Transition Metal Ion Homeostasis Insulin Receptor Signaling Pathway Cilium Assembly Cilium Organization Cellular Response To Insulin Stimulus Cilium Morphogenesis Proton Transport Pronephros Development Cell Projection Assembly Response To Insulin Otic Vesicle Formation Cellular Response To Peptide Hormone Stimulus Otic Vesicle Morphogenesis Cellular Response To Peptide Protein Localization To Cilium Otic Vesicle Development Intermediate Filament Organization Cellular Metal Ion Homeostasis Protein Transport Cellular Cation Homeostasis Establishment Of Protein Localization Cellular Ion Homeostasis Response To Peptide Hormone Organelle Organization Cellular Response To Organonitrogen Compound Metal Ion Homeostasis Organelle Assembly Response To Peptide Response To X-ray Cellular Chemical Homeostasis
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