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CXCR1 and GNA15
Number of citations of the paper that reports this interaction (PubMedID
9843397
)
0
Data Source:
HPRD
(in vivo)
CXCR1
GNA15
Description
C-X-C motif chemokine receptor 1
G protein subunit alpha 15
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
External Side Of Plasma Membrane
Membrane
Secretory Granule Membrane
Heterotrimeric G-protein Complex
Plasma Membrane
Synapse
Molecular Function
Interleukin-8 Receptor Activity
G Protein-coupled Receptor Activity
Chemokine Receptor Activity
Protein Binding
C-C Chemokine Receptor Activity
C-X-C Chemokine Receptor Activity
C-C Chemokine Binding
Interleukin-8 Binding
Nucleotide Binding
G Protein-coupled Receptor Binding
GTPase Activity
GTP Binding
Guanyl Nucleotide Binding
G-protein Beta/gamma-subunit Complex Binding
Metal Ion Binding
Biological Process
Dendritic Cell Chemotaxis
Chemotaxis
Immune Response
Signal Transduction
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Calcium-mediated Signaling
Neutrophil Chemotaxis
Receptor Internalization
Interleukin-8-mediated Signaling Pathway
Chemokine-mediated Signaling Pathway
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway
Calcium-mediated Signaling
Pathways
Chemokine receptors bind chemokines
G alpha (i) signalling events
Neutrophil degranulation
PLC beta mediated events
PLC beta mediated events
G-protein activation
Acetylcholine regulates insulin secretion
Acetylcholine regulates insulin secretion
G alpha (q) signalling events
G alpha (q) signalling events
ADP signalling through P2Y purinoceptor 1
ADP signalling through P2Y purinoceptor 1
Thromboxane signalling through TP receptor
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
Thrombin signalling through proteinase activated receptors (PARs)
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Drugs
Ketoprofen
Diseases
GWAS
Basophil count (
32888494
)
Diffusing capacity of carbon monoxide (
30694715
)
Idiopathic intracranial hypertension (
29608535
)
Inflammatory bowel disease (
23128233
28067908
)
Lymphocyte percentage of white cells (
32888494
)
Neutrophil count (
29403010
)
Smooth-surface caries (
23470693
)
White blood cell count (
29403010
)
Asthma (
31959851
32296059
34103634
)
Clozapine-induced myocarditis in schizophrenia (
32066683
)
Glucose homeostasis traits (
25524916
)
Heart failure (
20445134
)
Mean corpuscular volume (
32888494
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Neutrophil count (
32888494
)
White blood cell count (
32888494
)
Interacting Genes
20 interacting genes:
ADRA1A
CDK1
CLDND1
CXCL1
CXCL2
CXCL3
CXCL5
CXCL6
CXCL8
CXCR2
FATE1
GNA14
GNA15
GNAI2
IGFBP5
PDCD6IP
PPBP
TRARG1
TUBA1A
UBE2C
19 interacting genes:
ADRB2
APP
CHRM2
CNR1
CNR2
CXCR1
CXCR2
F2R
GRK2
GRM2
GRM4
HRH4
LTB4R
OPRD1
OPRK1
OPRM1
PRKCA
RGS2
TTC1
Entrez ID
3577
2769
HPRD ID
00908
00760
Ensembl ID
ENSG00000163464
ENSG00000060558
Uniprot IDs
P25024
P30679
PDB IDs
1ILP
1ILQ
2LNL
6XMN
8IC0
Enriched GO Terms of Interacting Partners
?
Chemokine Activity
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Cell Chemotaxis
Neutrophil Chemotaxis
Neutrophil Migration
Granulocyte Chemotaxis
Antimicrobial Humoral Response
Granulocyte Migration
CXCR Chemokine Receptor Binding
Chemotaxis
Cytokine Activity
Locomotion
Inflammatory Response
Myeloid Leukocyte Migration
Leukocyte Chemotaxis
Humoral Immune Response
Cell Migration
Cell Motility
Leukocyte Migration
Killing Of Cells Of Another Organism
Guanyl Nucleotide Binding
G Protein-coupled Receptor Signaling Pathway
G-protein Beta/gamma-subunit Complex Binding
Cell Killing
Neutrophil Activation
Heterotrimeric G-protein Complex
Signal Transduction
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Defense Response
Defense Response To Symbiont
Defense Response To Other Organism
Response To Molecule Of Bacterial Origin
Immune Response
Cellular Response To Oxygen-containing Compound
Cellular Response To Lipopolysaccharide
GTP Binding
Extracellular Region
Cellular Response To Molecule Of Bacterial Origin
G Protein-coupled Receptor Binding
Protein Polymerization
Cell Division
Extracellular Space
Response To Other Organism
Microtubule Polymerization
G Protein-coupled Acetylcholine Receptor Signaling Pathway
Regulation Of Cell Population Proliferation
Response To Lipopolysaccharide
Myeloid Leukocyte Activation
D-glucose Transmembrane Transport
Response To External Biotic Stimulus
G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Activity
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Signal Transduction
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Trans-synaptic Signaling
Synaptic Signaling
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Plasma Membrane
Cell-cell Signaling
G Protein-coupled Acetylcholine Receptor Signaling Pathway
Signaling
Regulation Of MAPK Cascade
Cell Communication
G Protein-coupled Opioid Receptor Activity
Regulation Of System Process
Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway
G Protein-coupled Peptide Receptor Activity
G Protein-coupled Opioid Receptor Signaling Pathway
Acetylcholine Receptor Signaling Pathway
Postsynaptic Membrane
Regulation Of Muscle System Process
Postsynaptic Signal Transduction
Regulation Of Biological Quality
Glutamate Receptor Signaling Pathway
Positive Regulation Of MAPK Cascade
Dendrite
Adult Behavior
Regulation Of G Protein-coupled Receptor Signaling Pathway
Regulation Of Smooth Muscle Contraction
Modulation Of Chemical Synaptic Transmission
Membrane
Chemical Synaptic Transmission
Regulation Of Muscle Contraction
Cannabinoid Receptor Activity
Trans-synaptic Signaling By Endocannabinoid, Modulating Synaptic Transmission
Interleukin-8-mediated Signaling Pathway
Interleukin-8 Receptor Activity
Negative Regulation Of Muscle Contraction
Regulation Of Amine Transport
Neuronal Dense Core Vesicle
Regulation Of Transport
Neuropeptide Binding
Synapse
Cannabinoid Signaling Pathway
Interleukin-8 Binding
G-protein Alpha-subunit Binding
Presynapse
Neuropeptide Signaling Pathway
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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