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CXCR1 and CXCL3
Number of citations of the paper that reports this interaction (PubMedID
8702798
)
0
Data Source:
HPRD
(in vitro, in vivo)
CXCR1
CXCL3
Description
C-X-C motif chemokine receptor 1
C-X-C motif chemokine ligand 3
Image
GO Annotations
Cellular Component
Plasma Membrane
External Side Of Plasma Membrane
Membrane
Secretory Granule Membrane
Extracellular Region
Extracellular Space
Molecular Function
Interleukin-8 Receptor Activity
G Protein-coupled Receptor Activity
Chemokine Receptor Activity
Protein Binding
C-C Chemokine Receptor Activity
C-X-C Chemokine Receptor Activity
C-C Chemokine Binding
Interleukin-8 Binding
Cytokine Activity
Chemokine Activity
Biological Process
Dendritic Cell Chemotaxis
Chemotaxis
Immune Response
Signal Transduction
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Calcium-mediated Signaling
Neutrophil Chemotaxis
Receptor Internalization
Interleukin-8-mediated Signaling Pathway
Chemokine-mediated Signaling Pathway
Chemotaxis
Defense Response
Inflammatory Response
Immune Response
Signal Transduction
Neutrophil Chemotaxis
Killing Of Cells Of Another Organism
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways
Chemokine receptors bind chemokines
G alpha (i) signalling events
Neutrophil degranulation
Chemokine receptors bind chemokines
G alpha (i) signalling events
Drugs
Ketoprofen
Diseases
GWAS
Basophil count (
32888494
)
Diffusing capacity of carbon monoxide (
30694715
)
Idiopathic intracranial hypertension (
29608535
)
Inflammatory bowel disease (
23128233
28067908
)
Lymphocyte percentage of white cells (
32888494
)
Neutrophil count (
29403010
)
Smooth-surface caries (
23470693
)
White blood cell count (
29403010
)
Inflammatory bowel disease (
23128233
)
Urate levels (BMI interaction) (
25811787
)
Interacting Genes
20 interacting genes:
ADRA1A
CDK1
CLDND1
CXCL1
CXCL2
CXCL3
CXCL5
CXCL6
CXCL8
CXCR2
FATE1
GNA14
GNA15
GNAI2
IGFBP5
PDCD6IP
PPBP
TRARG1
TUBA1A
UBE2C
6 interacting genes:
CCL11
CXCL5
CXCL6
CXCR1
CXCR2
XCL2
Entrez ID
3577
2921
HPRD ID
00908
00742
Ensembl ID
ENSG00000163464
ENSG00000163734
Uniprot IDs
P25024
P19876
PDB IDs
1ILP
1ILQ
2LNL
6XMN
8IC0
8XWF
8XX3
Enriched GO Terms of Interacting Partners
?
Chemokine Activity
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Cell Chemotaxis
Neutrophil Chemotaxis
Neutrophil Migration
Granulocyte Chemotaxis
Antimicrobial Humoral Response
Granulocyte Migration
CXCR Chemokine Receptor Binding
Chemotaxis
Cytokine Activity
Locomotion
Inflammatory Response
Myeloid Leukocyte Migration
Leukocyte Chemotaxis
Humoral Immune Response
Cell Migration
Cell Motility
Leukocyte Migration
Killing Of Cells Of Another Organism
Guanyl Nucleotide Binding
G Protein-coupled Receptor Signaling Pathway
G-protein Beta/gamma-subunit Complex Binding
Cell Killing
Neutrophil Activation
Heterotrimeric G-protein Complex
Signal Transduction
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Defense Response
Defense Response To Symbiont
Defense Response To Other Organism
Response To Molecule Of Bacterial Origin
Immune Response
Cellular Response To Oxygen-containing Compound
Cellular Response To Lipopolysaccharide
GTP Binding
Extracellular Region
Cellular Response To Molecule Of Bacterial Origin
G Protein-coupled Receptor Binding
Protein Polymerization
Cell Division
Extracellular Space
Response To Other Organism
Microtubule Polymerization
G Protein-coupled Acetylcholine Receptor Signaling Pathway
Regulation Of Cell Population Proliferation
Response To Lipopolysaccharide
Myeloid Leukocyte Activation
D-glucose Transmembrane Transport
Response To External Biotic Stimulus
Cell Chemotaxis
Granulocyte Chemotaxis
Chemokine-mediated Signaling Pathway
Granulocyte Migration
Chemotaxis
Locomotion
Myeloid Leukocyte Migration
Leukocyte Chemotaxis
Chemokine Activity
Neutrophil Chemotaxis
Leukocyte Migration
Neutrophil Migration
Cell Migration
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Cytokine-mediated Signaling Pathway
Cell Motility
Interleukin-8-mediated Signaling Pathway
Immune Response
Interleukin-8 Receptor Activity
Antimicrobial Humoral Response
Inflammatory Response
Interleukin-8 Binding
Cytokine Activity
Humoral Immune Response
G Protein-coupled Receptor Signaling Pathway
Immune System Process
C-X-C Chemokine Receptor Activity
CXCR Chemokine Receptor Binding
Dendritic Cell Chemotaxis
Defense Response
Chemokine Receptor Activity
C-C Chemokine Binding
C-C Chemokine Receptor Activity
Dendritic Cell Migration
CCR Chemokine Receptor Binding
Neutrophil Activation
Defense Response To Symbiont
Defense Response To Other Organism
Cell Surface Receptor Signaling Pathway
Signal Transduction
Response To Other Organism
Receptor Internalization
Response To External Biotic Stimulus
Secretory Granule Membrane
Mononuclear Cell Migration
Extracellular Space
Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium
Myeloid Leukocyte Activation
Response To Stress
Mammary Duct Terminal End Bud Growth
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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