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CXCR1 and CXCL6
Number of citations of the paper that reports this interaction (PubMedID
9692902
)
0
Data Source:
HPRD
(in vivo)
CXCR1
CXCL6
Description
C-X-C motif chemokine receptor 1
C-X-C motif chemokine ligand 6
Image
GO Annotations
Cellular Component
Plasma Membrane
External Side Of Plasma Membrane
Membrane
Secretory Granule Membrane
Extracellular Region
Extracellular Space
Molecular Function
Interleukin-8 Receptor Activity
G Protein-coupled Receptor Activity
Chemokine Receptor Activity
Protein Binding
C-C Chemokine Receptor Activity
C-X-C Chemokine Receptor Activity
C-C Chemokine Binding
Interleukin-8 Binding
Cytokine Activity
Protein Binding
Chemokine Activity
Heparin Binding
CXCR Chemokine Receptor Binding
Biological Process
Dendritic Cell Chemotaxis
Chemotaxis
Immune Response
Signal Transduction
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Calcium-mediated Signaling
Neutrophil Chemotaxis
Receptor Internalization
Interleukin-8-mediated Signaling Pathway
Chemokine-mediated Signaling Pathway
Leukocyte Homeostasis
Chemotaxis
Defense Response
Inflammatory Response
Immune Response
Signal Transduction
Cell-cell Signaling
Neutrophil Chemotaxis
Response To Lipopolysaccharide
Regulation Of Chemokine Production
Neutrophil Activation
Defense Response To Bacterium
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Chemokine-mediated Signaling Pathway
Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium
Cellular Response To Lipopolysaccharide
Antibacterial Innate Immune Response
Pathways
Chemokine receptors bind chemokines
G alpha (i) signalling events
Neutrophil degranulation
Chemokine receptors bind chemokines
G alpha (i) signalling events
Drugs
Ketoprofen
Diseases
GWAS
Basophil count (
32888494
)
Diffusing capacity of carbon monoxide (
30694715
)
Idiopathic intracranial hypertension (
29608535
)
Inflammatory bowel disease (
23128233
28067908
)
Lymphocyte percentage of white cells (
32888494
)
Neutrophil count (
29403010
)
Smooth-surface caries (
23470693
)
White blood cell count (
29403010
)
Basophil percentage of granulocytes (
27863252
)
Basophil percentage of white cells (
32888494
)
Blood protein levels in cardiovascular risk (
28369058
)
Eosinophil percentage of granulocytes (
27863252
)
Granulocyte count (
27863252
)
Granulocyte percentage of myeloid white cells (
27863252
)
Inflammatory bowel disease (
23128233
)
Lymphocyte percentage of white cells (
27863252
32888494
)
Monocyte percentage of white cells (
32888494
27863252
)
Myeloid white cell count (
27863252
)
Neonatal cytokine/chemokine levels (fetal genetic effect) (
30134952
)
Neutrophil count (
32888494
27863252
)
Neutrophil percentage of granulocytes (
27863252
)
Neutrophil percentage of white cells (
27863252
32888494
)
Sum basophil neutrophil counts (
27863252
)
Sum neutrophil eosinophil counts (
27863252
)
White blood cell count (
27863252
32888494
)
Interacting Genes
20 interacting genes:
ADRA1A
CDK1
CLDND1
CXCL1
CXCL2
CXCL3
CXCL5
CXCL6
CXCL8
CXCR2
FATE1
GNA14
GNA15
GNAI2
IGFBP5
PDCD6IP
PPBP
TRARG1
TUBA1A
UBE2C
14 interacting genes:
CCL11
CCL5
CCL7
CCL8
CXCL1
CXCL10
CXCL12
CXCL2
CXCL3
CXCR1
CXCR2
MMP9
PF4
PPBP
Entrez ID
3577
6372
HPRD ID
00908
00735
Ensembl ID
ENSG00000163464
ENSG00000124875
Uniprot IDs
P25024
P80162
PDB IDs
1ILP
1ILQ
2LNL
6XMN
8IC0
8XWM
8XXX
Enriched GO Terms of Interacting Partners
?
Chemokine Activity
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Cell Chemotaxis
Neutrophil Chemotaxis
Neutrophil Migration
Granulocyte Chemotaxis
Antimicrobial Humoral Response
Granulocyte Migration
CXCR Chemokine Receptor Binding
Chemotaxis
Cytokine Activity
Locomotion
Inflammatory Response
Myeloid Leukocyte Migration
Leukocyte Chemotaxis
Humoral Immune Response
Cell Migration
Cell Motility
Leukocyte Migration
Killing Of Cells Of Another Organism
Guanyl Nucleotide Binding
G Protein-coupled Receptor Signaling Pathway
G-protein Beta/gamma-subunit Complex Binding
Cell Killing
Neutrophil Activation
Heterotrimeric G-protein Complex
Signal Transduction
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Defense Response
Defense Response To Symbiont
Defense Response To Other Organism
Response To Molecule Of Bacterial Origin
Immune Response
Cellular Response To Oxygen-containing Compound
Cellular Response To Lipopolysaccharide
GTP Binding
Extracellular Region
Cellular Response To Molecule Of Bacterial Origin
G Protein-coupled Receptor Binding
Protein Polymerization
Cell Division
Extracellular Space
Response To Other Organism
Microtubule Polymerization
G Protein-coupled Acetylcholine Receptor Signaling Pathway
Regulation Of Cell Population Proliferation
Response To Lipopolysaccharide
Myeloid Leukocyte Activation
D-glucose Transmembrane Transport
Response To External Biotic Stimulus
Chemokine Activity
Cell Chemotaxis
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Chemotaxis
Locomotion
Granulocyte Chemotaxis
Leukocyte Chemotaxis
Granulocyte Migration
Antimicrobial Humoral Response
Cytokine Activity
Myeloid Leukocyte Migration
Leukocyte Migration
Cell Migration
Humoral Immune Response
Cell Motility
Killing Of Cells Of Another Organism
Chemokine-mediated Signaling Pathway
Cell Killing
Inflammatory Response
Immune Response
Defense Response To Symbiont
Defense Response To Other Organism
Mononuclear Cell Migration
Neutrophil Chemotaxis
Response To External Biotic Stimulus
Immune System Process
Defense Response
Cytokine-mediated Signaling Pathway
Neutrophil Migration
Extracellular Space
Response To Other Organism
G Protein-coupled Receptor Signaling Pathway
CXCR Chemokine Receptor Binding
Extracellular Region
Eosinophil Chemotaxis
Eosinophil Migration
Signal Transduction
CCR Chemokine Receptor Binding
Positive Regulation Of Lymphocyte Migration
Response To Stress
Positive Regulation Of Leukocyte Migration
Positive Regulation Of Cell Migration
Positive Regulation Of Cell Motility
Positive Regulation Of Locomotion
Regulation Of Lymphocyte Migration
Cell Surface Receptor Signaling Pathway
Intracellular Calcium Ion Homeostasis
Dendritic Cell Chemotaxis
Calcium Ion Homeostasis
Interleukin-8-mediated Signaling Pathway
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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