Wiki-Pi
About
Search
People
Updates
Search
CXCR1 and PPBP
Number of citations of the paper that reports this interaction (PubMedID
8195702
)
0
Data Source:
HPRD
(in vivo, in vitro)
CXCR1
PPBP
Description
C-X-C motif chemokine receptor 1
pro-platelet basic protein
Image
GO Annotations
Cellular Component
Plasma Membrane
External Side Of Plasma Membrane
Membrane
Secretory Granule Membrane
Extracellular Region
Extracellular Space
Platelet Alpha Granule
Platelet Alpha Granule Lumen
Tertiary Granule Lumen
Molecular Function
Interleukin-8 Receptor Activity
G Protein-coupled Receptor Activity
Chemokine Receptor Activity
Protein Binding
C-C Chemokine Receptor Activity
C-X-C Chemokine Receptor Activity
C-C Chemokine Binding
Interleukin-8 Binding
Cytokine Activity
Protein Binding
Chemokine Activity
Growth Factor Activity
CXCR Chemokine Receptor Binding
D-glucose Transmembrane Transporter Activity
Biological Process
Dendritic Cell Chemotaxis
Chemotaxis
Immune Response
Signal Transduction
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Calcium-mediated Signaling
Neutrophil Chemotaxis
Receptor Internalization
Interleukin-8-mediated Signaling Pathway
Chemokine-mediated Signaling Pathway
Chemotaxis
Defense Response
Inflammatory Response
Immune Response
Signal Transduction
Neutrophil Chemotaxis
Killing Of Cells Of Another Organism
Defense Response To Bacterium
Positive Regulation Of Cell Division
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Cellular Response To Lipopolysaccharide
D-glucose Transmembrane Transport
Pathways
Chemokine receptors bind chemokines
G alpha (i) signalling events
Neutrophil degranulation
Platelet degranulation
Chemokine receptors bind chemokines
G alpha (i) signalling events
Neutrophil degranulation
Drugs
Ketoprofen
Ethanesulfonic acid
Copper
Diseases
GWAS
Basophil count (
32888494
)
Diffusing capacity of carbon monoxide (
30694715
)
Idiopathic intracranial hypertension (
29608535
)
Inflammatory bowel disease (
23128233
28067908
)
Lymphocyte percentage of white cells (
32888494
)
Neutrophil count (
29403010
)
Smooth-surface caries (
23470693
)
White blood cell count (
29403010
)
Metabolite levels (
22916037
)
Interacting Genes
20 interacting genes:
ADRA1A
CDK1
CLDND1
CXCL1
CXCL2
CXCL3
CXCL5
CXCL6
CXCL8
CXCR2
FATE1
GNA14
GNA15
GNAI2
IGFBP5
PDCD6IP
PPBP
TRARG1
TUBA1A
UBE2C
32 interacting genes:
CCL13
CCL21
CCL26
CCL28
CCL5
CCL8
CELF1
CMTM6
COPG1
COPS7A
COX17
CTSG
CXCL10
CXCL11
CXCL12
CXCL14
CXCL6
CXCL9
CXCR1
CXCR2
DMWD
EFNA1
MAPK6
MOB3B
NDUFB11
NR4A1
PLEKHJ1
PMAIP1
RAB10
RPS27
SCFD1
STRN4
Entrez ID
3577
5473
HPRD ID
00908
07171
Ensembl ID
ENSG00000163464
ENSG00000163736
Uniprot IDs
P25024
P02775
PDB IDs
1ILP
1ILQ
2LNL
6XMN
8IC0
1F9P
1NAP
1TVX
Enriched GO Terms of Interacting Partners
?
Chemokine Activity
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Cell Chemotaxis
Neutrophil Chemotaxis
Neutrophil Migration
Granulocyte Chemotaxis
Antimicrobial Humoral Response
Granulocyte Migration
CXCR Chemokine Receptor Binding
Chemotaxis
Cytokine Activity
Locomotion
Inflammatory Response
Myeloid Leukocyte Migration
Leukocyte Chemotaxis
Humoral Immune Response
Cell Migration
Cell Motility
Leukocyte Migration
Killing Of Cells Of Another Organism
Guanyl Nucleotide Binding
G Protein-coupled Receptor Signaling Pathway
G-protein Beta/gamma-subunit Complex Binding
Cell Killing
Neutrophil Activation
Heterotrimeric G-protein Complex
Signal Transduction
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Defense Response
Defense Response To Symbiont
Defense Response To Other Organism
Response To Molecule Of Bacterial Origin
Immune Response
Cellular Response To Oxygen-containing Compound
Cellular Response To Lipopolysaccharide
GTP Binding
Extracellular Region
Cellular Response To Molecule Of Bacterial Origin
G Protein-coupled Receptor Binding
Protein Polymerization
Cell Division
Extracellular Space
Response To Other Organism
Microtubule Polymerization
G Protein-coupled Acetylcholine Receptor Signaling Pathway
Regulation Of Cell Population Proliferation
Response To Lipopolysaccharide
Myeloid Leukocyte Activation
D-glucose Transmembrane Transport
Response To External Biotic Stimulus
Chemokine Activity
Cell Chemotaxis
Leukocyte Chemotaxis
Chemokine-mediated Signaling Pathway
Chemotaxis
Locomotion
Antimicrobial Humoral Response
Granulocyte Chemotaxis
Leukocyte Migration
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Myeloid Leukocyte Migration
Granulocyte Migration
Humoral Immune Response
Cytokine Activity
Killing Of Cells Of Another Organism
Cell Migration
Cytokine-mediated Signaling Pathway
Mononuclear Cell Migration
Cell Motility
Cell Killing
CXCR Chemokine Receptor Binding
Inflammatory Response
Eosinophil Chemotaxis
Defense Response To Symbiont
Eosinophil Migration
Defense Response
Defense Response To Other Organism
Immune System Process
Neutrophil Chemotaxis
Immune Response
CCR Chemokine Receptor Binding
Chemokine Receptor Binding
Neutrophil Migration
Response To External Biotic Stimulus
Response To Other Organism
Cell-cell Signaling
G Protein-coupled Receptor Signaling Pathway
Signaling
Cell Communication
T Cell Chemotaxis
Dendritic Cell Chemotaxis
Negative Regulation Of Leukocyte Tethering Or Rolling
CXCR3 Chemokine Receptor Binding
Dendritic Cell Migration
Lymphocyte Chemotaxis
Neutrophil Activation
Negative Regulation Of Cellular Extravasation
T Cell Migration
Positive Regulation Of T Cell Migration
Extracellular Space
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?