CCDC158 and NAGK

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CCDC158	NAGK
Description		coiled-coil domain containing 158	N-acetylglucosamine kinase
Image		No pdb structure
GO Annotations	Cellular Component	Early Endosome Clathrin-coated Vesicle	Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Clathrin Binding	Nucleotide Binding Protein Binding ATP Binding N-acylmannosamine Kinase Activity Kinase Activity Transferase Activity N-acetylglucosamine Kinase Activity Muramyl Dipeptide Kinase Activity
	Biological Process	Receptor-mediated Endocytosis	Immune System Process N-acetylglucosamine Metabolic Process N-acetylglucosamine Catabolic Process UDP-N-acetylglucosamine Biosynthetic Process N-acetylmannosamine Metabolic Process Canonical NF-kappaB Signal Transduction N-acetylneuraminate Catabolic Process Response To Muramyl Dipeptide P38MAPK Cascade Defense Response To Bacterium Positive Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Canonical NF-kappaB Signal Transduction Innate Immune Response Carbohydrate Phosphorylation Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Positive Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Protein K63-linked Ubiquitination Protein Linear Polyubiquitination
Pathways			Synthesis of UDP-N-acetyl-glucosamine
Drugs			N-Acetylglucosamine
Diseases
GWAS		Chronic kidney disease ( 20383146) Estimated glomerular filtration rate ( 31015462)	Blood protein levels ( 30072576) Erythema nodosum in inflammatory bowel disease ( 24487271)
Interacting Genes		11 interacting genes: C1orf216 DESI1 FCHSD2 GPSM1 NAGK NUTF2 SGF29 SH3GLB2 TBC1D21 TNPO2 UBQLN2	36 interacting genes: ACTR10 ANKRD1 CCDC158 CDKN2C CEP43 DACH1 DCP2 DSCR9 DYNC1I1 FNDC3B GNPNAT1 LACTB2 LENG1 LMO1 LNX1 LNX2 LSM8 MEOX1 MTHFD2 NTAQ1 NUDC PJA1 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 SRPK2 STK16 SYNE4 TCF12 TNNT1 WDR82
Entrez ID		339965	55577
HPRD ID		13395	08441
Ensembl ID		ENSG00000163749	ENSG00000124357
Uniprot IDs		A0A804HIY6 Q5M9N0	A0A384N6G7 C9JEV6 Q9UJ70
PDB IDs			2CH5 2CH6
Enriched GO Terms of Interacting Partners?		Nuclear Import Signal Receptor Activity Stereocilium Shaft Establishment Of Protein Localization Nuclear Transport Nucleocytoplasmic Transport Small GTPase Binding Protein Export From Nucleus N-acetylglucosamine Kinase Activity Muramyl Dipeptide Kinase Activity Establishment Of Protein Localization To Organelle Negative Regulation Of G Protein-coupled Receptor Internalization N-acylmannosamine Kinase Activity N-acetylmannosamine Metabolic Process	Nucleoplasm Transcription Regulator Complex Negative Regulation Of DNA Biosynthetic Process Heteromeric SMAD Protein Complex SMAD Protein Complex Cytoplasm Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process HMG Box Domain Binding Nucleus Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process I-SMAD Binding Response To Transforming Growth Factor Beta Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Nucleobase-containing Compound Metabolic Process
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