CCDC158 and GPSM1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		CCDC158	GPSM1
Description		coiled-coil domain containing 158	G protein signaling modulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Early Endosome Clathrin-coated Vesicle	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Plasma Membrane Cell Cortex Membrane Protein-containing Complex
	Molecular Function	Protein Binding Clathrin Binding	G-protein Alpha-subunit Binding GDP-dissociation Inhibitor Activity Protein Binding GTPase Regulator Activity
	Biological Process	Receptor-mediated Endocytosis	Establishment Of Mitotic Spindle Orientation Nervous System Development Positive Regulation Of Macroautophagy Cell Differentiation Negative Regulation Of GTPase Activity Negative Regulation Of Guanyl-nucleotide Exchange Factor Activity
Pathways			G alpha (i) signalling events
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Estimated glomerular filtration rate ( 31015462)	Acute insulin response (insulin secretion adjusted) ( 28490609) Birth weight ( 31043758) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Insulinogenic index ( 23263489) Joint damage in rheumatoid arthritis ( 26498133) Myocardial infarction ( 33532862) Offspring birth weight ( 31043758) Type 2 diabetes ( 23945395 32499647 31118516 30718926 30297969 29632382 28869590 26818947) Type 2 diabetes (adjusted for BMI) ( 29632382) Ulcerative colitis ( 28067908) White blood cell count ( 29403010)
Interacting Genes		11 interacting genes: C1orf216 DESI1 FCHSD2 GPSM1 NAGK NUTF2 SGF29 SH3GLB2 TBC1D21 TNPO2 UBQLN2	28 interacting genes: BHLHE40 CCDC158 CTDSP1 DAZAP2 DCAF11 DMRT3 FAM161B FAM83A FAM90A1 FXR2 GCM2 GLIS2 GNAI1 GNAI3 HMG20A INSC KANK2 MAP1LC3A OSTM1 RIBC1 SEPTIN1 TASOR2 TEKT4 TRIP13 USHBP1 USP9X VEZF1 ZBED1
Entrez ID		339965	26086
HPRD ID		13395	17075
Ensembl ID		ENSG00000163749	ENSG00000160360
Uniprot IDs		A0A804HIY6 Q5M9N0	A0A087WVF5 A0A0A0MSK4 Q86YR5
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear Import Signal Receptor Activity Stereocilium Shaft Establishment Of Protein Localization Nuclear Transport Nucleocytoplasmic Transport Small GTPase Binding Protein Export From Nucleus N-acetylglucosamine Kinase Activity Muramyl Dipeptide Kinase Activity Establishment Of Protein Localization To Organelle Negative Regulation Of G Protein-coupled Receptor Internalization N-acylmannosamine Kinase Activity N-acetylmannosamine Metabolic Process
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