CCDC158 and TNPO2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCDC158	TNPO2
Description		coiled-coil domain containing 158	transportin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Early Endosome Clathrin-coated Vesicle	Nucleus Cytoplasm
	Molecular Function	Protein Binding Clathrin Binding	Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity
	Biological Process	Receptor-mediated Endocytosis	Protein Import Into Nucleus Intracellular Protein Transport Protein Transport Negative Regulation Of Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Estimated glomerular filtration rate ( 31015462)	Diffuse large B-cell lymphoma or multiple sclerosis ( 31407831)
Interacting Genes		11 interacting genes: C1orf216 DESI1 FCHSD2 GPSM1 NAGK NUTF2 SGF29 SH3GLB2 TBC1D21 TNPO2 UBQLN2	54 interacting genes: A1CF APIP BEND7 BIRC7 BIRC8 BLMH C1orf94 CAMK2B CAMK2D CAMK2G CCDC158 CEBPA CRYAB CTAG1A CTAG1B ELAVL1 EXOC5 FH FTO FUCA2 GCH1 GSC2 KLHL2 KLHL20 KLHL3 KRT75 KRTAP8-1 NME1 NUP98 NXF1 OTX2 PACSIN3 PDLIM7 PIK3CD PINX1 PNMA5 POU6F2 PRMT8 PYCR1 RBM45 REDIC1 RIPK4 RNF10 RPL4 RPRD1B SERTAD3 SF1 TBX2 TCL1B TERF1 THAP6 TRIM8 ZBTB32 ZC2HC1C
Entrez ID		339965	30000
HPRD ID		13395	04301
Ensembl ID		ENSG00000163749	ENSG00000105576
Uniprot IDs		A0A804HIY6 Q5M9N0	O14787 Q05D48
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear Import Signal Receptor Activity Stereocilium Shaft Establishment Of Protein Localization Nuclear Transport Nucleocytoplasmic Transport Small GTPase Binding Protein Export From Nucleus N-acetylglucosamine Kinase Activity Muramyl Dipeptide Kinase Activity Establishment Of Protein Localization To Organelle Negative Regulation Of G Protein-coupled Receptor Internalization N-acylmannosamine Kinase Activity N-acetylmannosamine Metabolic Process	Identical Protein Binding Calcium- And Calmodulin-dependent Protein Kinase Complex Protein Binding Calcium/calmodulin-dependent Protein Kinase Activity Protein Homodimerization Activity
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