Wiki-Pi
About
Search
People
Updates
Search
GYS1 and PLAGL2
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
GYS1
PLAGL2
Description
glycogen synthase 1
PLAG1 like zinc finger 2
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Membrane
Inclusion Body
Nucleus
Molecular Function
Catalytic Activity
Alpha-1,4-glucan Glucosyltransferase (UDP-glucose Donor) Activity
Protein Binding
D-glucose Binding
Transferase Activity
Glycosyltransferase Activity
Glycogen Synthase Activity, Transferring Glucose-1-phosphate
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Sequence-specific DNA Binding
Metal Ion Binding
Biological Process
Glycogen Metabolic Process
Glycogen Biosynthetic Process
Heart Development
Regulation Of Transcription By RNA Polymerase II
Lipid Metabolic Process
Post-embryonic Development
Chylomicron Assembly
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Glycogen synthesis
Myoclonic epilepsy of Lafora
Glycogen storage disease type XV (GYG1)
Glycogen storage disease type 0 (muscle GYS1)
Drugs
Diseases
Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS
Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) (
30940143
)
Inflammatory bowel disease (
28067908
)
Interacting Genes
43 interacting genes:
AIMP2
APP
BEND7
CCDC33
CDCA8
CLVS2
CRX
CSNK2A1
EFHC2
FAM228A
GSK3B
GYG1
GYG2
HOXB6
HOXC8
IHO1
INCA1
KATNBL1
KLF1
KLF4
MAPKAPK5
MEOX1
NDUFB7
NHLRC1
PCYT1A
PINX1
PLAGL2
PNMA5
PRKACA
RBM48
SNIP1
SORBS3
SUMO2
TFAP2D
TLE5
WASHC1
ZBTB33
ZNF212
ZNF326
ZNF474
ZNF552
ZNF620
ZNF774
45 interacting genes:
ANKRD11
ARID5A
BCAS2
CATSPER1
CCDC120
CTNNA3
DAPP1
DHX57
DVL3
FAM161B
FAM83A
FAM90A1
GADD45G
GEM
GLYCTK
GPATCH2L
GYS1
INO80B
IRX2
KANK2
MAD2L2
MAPK1
MORN4
NOS1AP
OIP5
OLIG3
PAX9
PHC2
PIN1
PLAC8
PRR35
RCHY1
RHOBTB3
RIPPLY1
SAMD11
SEPHS1
SMARCD1
TEKT3
TEKT4
TRAF4
TRIM41
VEZF1
YPEL5
ZNF564
ZNF581
Entrez ID
2997
5326
HPRD ID
00721
05333
Ensembl ID
ENSG00000104812
ENSG00000126003
Uniprot IDs
P13807
Q9UPG8
PDB IDs
7Q0B
7Q0S
7Q12
7Q13
7ZBN
8CVX
8CVY
8CVZ
Enriched GO Terms of Interacting Partners
?
Nucleus
Regulation Of Transcription By RNA Polymerase II
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of Primary Metabolic Process
Regulation Of RNA Biosynthetic Process
Glycogenin Glucosyltransferase Activity
Regulation Of Macromolecule Metabolic Process
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Glycogen Biosynthetic Process
Glycogen Metabolic Process
Regulation Of RNA Metabolic Process
DNA Binding
Polysaccharide Biosynthetic Process
Protein Binding
Regulation Of Macromolecule Biosynthetic Process
DNA-binding Transcription Factor Activity
Energy Reserve Metabolic Process
Polysaccharide Metabolic Process
Regulation Of Metabolic Process
Regulation Of Gene Expression
Energy Derivation By Oxidation Of Organic Compounds
Regulation Of Protein Ubiquitination
Regulation Of Protein Metabolic Process
Cellular Response To Endothelin
Positive Regulation Of Apoptotic Process
Regulation Of Post-translational Protein Modification
Response To Endothelin
Positive Regulation Of Programmed Cell Death
Regulation Of Apoptotic Signaling Pathway
Wnt Signaling Pathway
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Positive Regulation Of Neuron Apoptotic Process
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Positive Regulation Of Transcription By RNA Polymerase II
Cellular Response To Laminar Fluid Shear Stress
Regulation Of Cell Cycle
Generation Of Precursor Metabolites And Energy
Positive Regulation Of Protein Export From Nucleus
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?