HSF2 and SUMO3

Number of citations of the paper that reports this interaction (PMID 16428449)
22

Data Source:
HPRD (in vitro)

		HSF2	SUMO3
Gene Name		heat shock transcription factor 2	small ubiquitin-like modifier 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Kinetochore Nucleus Nucleoplasm Cytoplasm PML Body Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Homodimerization Activity	Protein Binding SUMO Transferase Activity
	Biological Process	Transcription From RNA Polymerase II Promoter Spermatogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter	Protein Sumoylation Protein Localization To Nucleus Post-translational Protein Modification Cellular Protein Metabolic Process Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Pathways			SUMO is proteolytically processed Post-translational protein modification SUMOylation SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) Processing and activation of SUMO
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: CDC20 CDC27 CUL3 HSF1 HSF2BP MTUS2 NCAPG NUP62 PCGF2 PPP2R1A SUMO1 SUMO2 SUMO3 TPM3 UBE2I WDR5	53 interactors: ANXA7 ARL13A ARNTL ATF3 ATF7IP BCL11A BLM CCNE2 CDKN1A CEBPA CHAF1A CUL3 FOS HSF1 HSF2 JUN KALRN KCNA5 KRT14 KRT5 KRT8 MAPKAPK3 NFKBIA PFDN1 PIAS1 PIAS2 PIAS3 PIAS4 PML RANGAP1 SAE1 SATB1 SENP1 SENP2 SENP5 SH3KBP1 SMN1 SOX10 SOX6 SP100 STAB2 STK24 TDG TDP2 TK1 TP53BP2 TTR UBA2 UBE2I UBE3A UPF2 USPL1 VIM
Entrez ID		3298	6612
HPRD ID		00779	03754
Ensembl ID		ENSG00000025156	ENSG00000184900
Uniprot IDs		Q03933 Q9BS48	B4DUW4 P55854
PDB IDs			1U4A 2IO1
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Protein Sumoylation Protein Modification By Small Protein Conjugation Positive Regulation Of Protein Catabolic Process Peptidyl-lysine Modification Positive Regulation Of Proteolysis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Process Regulation Of Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Mitotic Cell Cycle Organelle Organization Cellular Protein Modification Process Cell Cycle Negative Regulation Of Transferase Activity Negative Regulation Of Cellular Metabolic Process Mitotic Nuclear Division Cell Cycle Process Regulation Of Proteolysis Regulation Of Mitotic Sister Chromatid Separation Regulation Of Mitotic Metaphase/anaphase Transition Cell Division Cellular Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Post-translational Protein Modification Regulation Of Cellular Protein Metabolic Process Nuclear Envelope Organization Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Chromosome Segregation Positive Regulation Of Proteasomal Protein Catabolic Process Peptidyl-amino Acid Modification Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Protein Metabolic Process Regulation Of Chromosome Segregation Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cellular Protein Metabolic Process Protein Metabolic Process Nucleus Organization Regulation Of Mitotic Nuclear Division Positive Regulation Of Protein Metabolic Process Cellular Metabolic Process Negative Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Ubiquitination Negative Regulation Of Catalytic Activity Negative Regulation Of Cellular Protein Metabolic Process	Protein Sumoylation Positive Regulation Of Metabolic Process Peptidyl-lysine Modification Positive Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Stimulus Negative Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Protein Desumoylation Cellular Metabolic Process Apoptotic Signaling Pathway RNA Biosynthetic Process Peptidyl-amino Acid Modification Developmental Process Apoptotic Process Programmed Cell Death Viral Process Transcription From RNA Polymerase II Promoter Cell Death Death RNA Metabolic Process Multicellular Organismal Development Response To Abiotic Stimulus System Development Regulation Of Cellular Process Cellular Response To Stimulus Cellular Response To Stress Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process
Tagcloud ?		abiotic ap2 brachiata characterisation chlorophyll dehydration dehydrins dreb electrolyte erd10b erd10d germination glutamic halophyte hsp18 hsp26 hyperionic hyperosmotic lea5 photosynthesis plc3 salicornia sbdreb2a tf tfs transgenics wildtype wue zfp	aphidicolin attachment break breakage budding cfs covalent excessive fields fragile hallmark modifier ortholog perturbed pol32 pold3 polypeptides proteomic recombinational replication resource rpa ssdna stresses subfamily sumo1 sumo2 sumoylation
Tagcloud (Difference) ?		abiotic ap2 brachiata characterisation chlorophyll dehydration dehydrins dreb electrolyte erd10b erd10d germination glutamic halophyte hsp18 hsp26 hyperionic hyperosmotic lea5 photosynthesis plc3 salicornia sbdreb2a tf tfs transgenics wildtype wue zfp	aphidicolin attachment break breakage budding cfs covalent excessive fields fragile hallmark modifier ortholog perturbed pol32 pold3 polypeptides proteomic recombinational replication resource rpa ssdna stresses subfamily sumo1 sumo2 sumoylation
Tagcloud (Intersection) ?