SUMO3 and RANGAP1

Number of citations of the paper that reports this interaction (PMID 16620772)
10

Data Source:
HPRD (in vivo)

		SUMO3	RANGAP1
Gene Name		small ubiquitin-like modifier 3	Ran GTPase activating protein 1
Image
Gene Ontology Annotations	Cellular Component	Kinetochore Nucleus Nucleoplasm Cytoplasm PML Body Extracellular Vesicular Exosome	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Nuclear Pore Cytoplasm Cytosol Nuclear Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding SUMO Transferase Activity	Ran GTPase Activator Activity Protein Binding
	Biological Process	Protein Sumoylation Protein Localization To Nucleus Post-translational Protein Modification Cellular Protein Metabolic Process Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process	Mitotic Cell Cycle Signal Transduction Positive Regulation Of Ran GTPase Activity Negative Regulation Of Protein Export From Nucleus
Pathways		SUMO is proteolytically processed Post-translational protein modification SUMOylation SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) Processing and activation of SUMO	Mitotic Prometaphase Separation of Sister Chromatids HIV Infection Host Interactions of HIV factors Rev-mediated nuclear export of HIV RNA Mitotic Anaphase Interactions of Rev with host cellular proteins M Phase Cell Cycle, Mitotic Late Phase of HIV Life Cycle HIV Life Cycle Rev-mediated nuclear export of HIV RNA Resolution of Sister Chromatid Cohesion Mitotic Metaphase and Anaphase
Drugs
Diseases
GWAS
Protein-Protein Interactions		53 interactors: ANXA7 ARL13A ARNTL ATF3 ATF7IP BCL11A BLM CCNE2 CDKN1A CEBPA CHAF1A CUL3 FOS HSF1 HSF2 JUN KALRN KCNA5 KRT14 KRT5 KRT8 MAPKAPK3 NFKBIA PFDN1 PIAS1 PIAS2 PIAS3 PIAS4 PML RANGAP1 SAE1 SATB1 SENP1 SENP2 SENP5 SH3KBP1 SMN1 SOX10 SOX6 SP100 STAB2 STK24 TDG TDP2 TK1 TP53BP2 TTR UBA2 UBE2I UBE3A UPF2 USPL1 VIM	14 interactors: CCL5 CSNK2A1 GNAI1 GNAI3 IPO8 RAN RANBP2 SENP1 SENP2 SUMO1 SUMO2 SUMO3 UBE2I USPL1
Entrez ID		6612	5905
HPRD ID		03754	03839
Ensembl ID		ENSG00000184900	ENSG00000100401
Uniprot IDs		B4DUW4 P55854	F8W7I9 P46060 Q9BSK3
PDB IDs		1U4A 2IO1	1Z5S 2GRN 2GRO 2GRP 2GRQ 2GRR 2IO2 2IO3 2IY0 3UIN 3UIO 3UIP
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Positive Regulation Of Metabolic Process Peptidyl-lysine Modification Positive Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Stimulus Negative Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Protein Desumoylation Cellular Metabolic Process Apoptotic Signaling Pathway RNA Biosynthetic Process Peptidyl-amino Acid Modification Developmental Process Apoptotic Process Programmed Cell Death Viral Process Transcription From RNA Polymerase II Promoter Cell Death Death RNA Metabolic Process Multicellular Organismal Development Response To Abiotic Stimulus System Development Regulation Of Cellular Process Cellular Response To Stimulus Cellular Response To Stress Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process	Protein Sumoylation Peptidyl-lysine Modification Protein Desumoylation Post-translational Protein Modification Peptidyl-amino Acid Modification Protein Modification By Small Protein Conjugation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Protein Modification Process Regulation Of Protein Catabolic Process Protein Localization To Nucleus Positive Regulation Of Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Proteolysis Protein Modification By Small Protein Removal Nucleus Organization Regulation Of Cellular Protein Metabolic Process Cell Cycle Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Cellular Metabolic Process Cell Division Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Protein Metabolic Process Signal Transduction Protein Localization To Organelle Protein Metabolic Process Signaling Cell Communication Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Regulation Of Binding Vesicle Fusion Protein Localization Metabolic Process Mitotic Cell Cycle Process Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of SUMO Transferase Activity Negative Regulation Of Proteasomal Protein Catabolic Process Nuclear Envelope Organization Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Protein Localization Mitotic Cell Cycle Positive Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Stimulus Negative Regulation Of Cellular Protein Catabolic Process
Tagcloud ?		aphidicolin attachment break breakage budding cfs covalent excessive fields fragile hallmark modifier ortholog perturbed pol32 pold3 polypeptides proteomic recombinational replication resource rpa ssdna stresses subfamily sumo1 sumo2 sumoylation	apl bodies compartmentalisation covalently dependant disrupted fits indirectly kr leukaemia localisation localises lys487 lys490 modification modifies mutagenesis named nd10 phosphoprotein pic1 pml pods promyelocytic rara subcellular sumo translocated ubc9
Tagcloud (Difference) ?		aphidicolin attachment break breakage budding cfs covalent excessive fields fragile hallmark modifier ortholog perturbed pol32 pold3 polypeptides proteomic recombinational replication resource rpa ssdna stresses subfamily sumo1 sumo2 sumoylation	apl bodies compartmentalisation covalently dependant disrupted fits indirectly kr leukaemia localisation localises lys487 lys490 modification modifies mutagenesis named nd10 phosphoprotein pic1 pml pods promyelocytic rara subcellular translocated ubc9
Tagcloud (Intersection) ?		sumo