SUMO3 and CEBPA

Number of citations of the paper that reports this interaction (PMID 12511558)
38

Data Source:
HPRD (in vitro, in vivo)

		SUMO3	CEBPA
Gene Name		small ubiquitin-like modifier 3	CCAAT/enhancer binding protein (C/EBP), alpha
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Kinetochore Nucleus Nucleoplasm Cytoplasm PML Body Extracellular Vesicular Exosome	Nucleus Nuclear Matrix Rb-E2F Complex
	Molecular Function	Protein Binding SUMO Transferase Activity	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Complex Binding Protein Homodimerization Activity Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity HMG Box Domain Binding
	Biological Process	Protein Sumoylation Protein Localization To Nucleus Post-translational Protein Modification Cellular Protein Metabolic Process Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process	Urea Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Liver Development Embryonic Placenta Development Generation Of Precursor Metabolites And Energy Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Acute-phase Response Mitochondrion Organization Cholesterol Metabolic Process Negative Regulation Of Cell Proliferation Viral Process Cytokine-mediated Signaling Pathway Myeloid Cell Differentiation Macrophage Differentiation Lung Development Organ Regeneration Response To Vitamin B2 Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase III Promoter Cell Maturation Inner Ear Development White Fat Cell Differentiation Brown Fat Cell Differentiation Response To Glucocorticoid Cellular Response To Lithium Ion Cellular Response To Organic Cyclic Compound
Pathways		SUMO is proteolytically processed Post-translational protein modification SUMOylation SUMO is conjugated to E1 (UBA2:SAE1) SUMO is transferred from E1 to E2 (UBE2I, UBC9) Processing and activation of SUMO	Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS
Protein-Protein Interactions		53 interactors: ANXA7 ARL13A ARNTL ATF3 ATF7IP BCL11A BLM CCNE2 CDKN1A CEBPA CHAF1A CUL3 FOS HSF1 HSF2 JUN KALRN KCNA5 KRT14 KRT5 KRT8 MAPKAPK3 NFKBIA PFDN1 PIAS1 PIAS2 PIAS3 PIAS4 PML RANGAP1 SAE1 SATB1 SENP1 SENP2 SENP5 SH3KBP1 SMN1 SOX10 SOX6 SP100 STAB2 STK24 TDG TDP2 TK1 TP53BP2 TTR UBA2 UBE2I UBE3A UPF2 USPL1 VIM	56 interactors: AR ATF2 ATF3 ATF4 ATF5 BATF BATF2 BATF3 C1QBP CDK2 CDK4 CDKN1A CDKN3 CDX1 CEBPB CEBPD CEBPE CEBPG CREBBP CTNNB1 DBP EDF1 EP300 ESR1 FOS FOSL1 GATA2 GSK3B HNF1A MAPK8 MSX2 MYC NCOA6 NFYA NR3C1 PIAS1 RARA RARB RASGRF1 RB1 RBL1 RFC1 RUNX1 SKP2 SMAD3 SMAD4 SMARCA2 SMARCA4 SOX10 SOX8 SPI1 SRA1 SUMO3 XRCC5 XRCC6 ZBTB16
Entrez ID		6612	1050
HPRD ID		03754	00296
Ensembl ID		ENSG00000184900	ENSG00000245848
Uniprot IDs		B4DUW4 P55854	P49715
PDB IDs		1U4A 2IO1
Enriched GO Terms of Interacting Partners?		Protein Sumoylation Positive Regulation Of Metabolic Process Peptidyl-lysine Modification Positive Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Stimulus Negative Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Protein Desumoylation Cellular Metabolic Process Apoptotic Signaling Pathway RNA Biosynthetic Process Peptidyl-amino Acid Modification Developmental Process Apoptotic Process Programmed Cell Death Viral Process Transcription From RNA Polymerase II Promoter Cell Death Death RNA Metabolic Process Multicellular Organismal Development Response To Abiotic Stimulus System Development Regulation Of Cellular Process Cellular Response To Stimulus Cellular Response To Stress Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process	Positive Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Biosynthetic Process Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Organ Development Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated System Development Multicellular Organismal Development Cellular Metabolic Process Anatomical Structure Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Cell Differentiation Regulation Of Cell Proliferation Regulation Of Cell Differentiation Tissue Development Myeloid Cell Differentiation Positive Regulation Of Cell Differentiation Regulation Of Cell Death Transcription Initiation From RNA Polymerase II Promoter
Tagcloud ?		aphidicolin attachment break breakage budding cfs covalent excessive fields fragile hallmark modifier ortholog perturbed pol32 pold3 polypeptides proteomic recombinational replication resource rpa ssdna stresses subfamily sumo1 sumo2 sumoylation	acting additive c38 c40 caat cebpb collectively commitment composed concert elusive embryonic enhancer epidermis evolutionary fate keratinocyte keratinocytes layer modules p63 p63lre partly pluripotent pou pou3f1 redundant repress robust
Tagcloud (Difference) ?		aphidicolin attachment break breakage budding cfs covalent excessive fields fragile hallmark modifier ortholog perturbed pol32 pold3 polypeptides proteomic recombinational replication resource rpa ssdna stresses subfamily sumo1 sumo2 sumoylation	acting additive c38 c40 caat cebpb collectively commitment composed concert elusive embryonic enhancer epidermis evolutionary fate keratinocyte keratinocytes layer modules p63 p63lre partly pluripotent pou pou3f1 redundant repress robust
Tagcloud (Intersection) ?