PRKACA and PDE4B

  • Number of citations of the paper that reports this interaction (PMID 12441002)
  • 6
  • Data Source:
  • HPRD (in vivo)

PRKACA

PDE4B

Gene Name protein kinase, cAMP-dependent, catalytic, alpha phosphodiesterase 4B, cAMP-specific
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute lymphoblastic leukemia (childhood) ( 23007406)
  • Echocardiographic traits ( 17903301)
  • Economic and political preferences (feminism/equality) ( 22566634)
Protein-Protein Interactions 181 interactors: AANAT ABCA1 ACLY ADCY5 ADD1 ADD2 ADRBK1 AKAP13 AKAP14 AKAP8L AKIP1 ANXA7 APC APOBEC3G ASIC1 ASIC3 ATF1 ATP2B1 AURKA BAD BCL2 BRAF CACNA1C CACNB2 CACNG2 CAD CALD1 CAMKK2 CCDC88A CCND1 CDK16 CETN1 CFTR CIITA CLDN3 CLTC CREB1 CREM CSK CUL5 CYP3A4 DMTN DNAJC5 DSP EEF2K EGFR ESR1 ETV1 FOS FXYD1 GABRB3 GABRR1 GAD1 GAD2 GFAP GJA5 GJB1 GMFB GNA13 GNMT GP1BB GRIA1 GRIA4 GSK3A GSK3B GUSB GYS1 HAND1 HAND2 HDAC1 HDAC8 HMGCR HMGN1 HMGN2 HNRNPD HSPD1 IFNAR1 IQGAP1 IRF2 ITCH ITGA2B ITGA4 ITPKA ITPKB ITPR1 ITPR2 KCNH2 KCNJ12 KCNQ1 KLF1 LCK LCP1 LIPE LRP1 MAP2 MAP3K3 MAPT MBP MC4R MEF2D MEP1B MGMT MIP NDRG1 NFKB1 NIN NOLC1 NOS1 NOXA1 NR3C1 NUP85 PARK2 PDC PDE3B PDE4B PDE4D PDPK1 PFKFB1 PFKFB2 PHKA1 PHOX2A PKIA PLIN1 PLN POU2F1 PPP1R10 PPP1R17 PPP1R1B PPP1R8 PPP1R9B PRKAR1A PSEN1 PTBP1 PTPN12 PTPN13 PTPN7 PTPRR RAF1 RANBP9 RAP1A RAP1B RAP1GAP RASGRF1 RASGRP3 RELA RGS10 RGS13 RGS14 RHOA RRAD RSBN1 RYR1 RYR2 SI SIK1 SIK3 SLC2A2 SLC4A4 SLC9A3R2 SNAP25 SNAPIN SPTBN1 SRC STK11 STMN1 STMN2 SYN1 SYN2 TBXA2R TCF3 TH THOP1 TNP1 TNP2 TPH1 TRIP10 UHRF1 VASP VIM VTN WT1 4 interactors: DISC1 MAGEA11 PRKACA RCBTB2
Entrez ID 5566 5142
HPRD ID 03382 02528
Ensembl ID ENSG00000072062 ENSG00000184588
Uniprot IDs P17612 Q07343 Q59GM8
PDB IDs 2GU8 3AGL 3AGM 3AMA 3AMB 3L9L 3L9M 3L9N 3MVJ 3NX8 3OOG 3OVV 3OWP 3OXT 3P0M 3POO 3VQH 4AE6 4AE9 1F0J 1JP1 1JP2 1RO6 1RO9 1ROR 1TB5 1XLX 1XLZ 1XM4 1XM6 1XMU 1XMY 1XN0 1XOS 1XOT 1Y2H 1Y2J 2CHM 2QYL 3D3P 3FRG 3G45 3GWT 3HC8 3HDZ 3HMV 3KKT 3LY2 3O0J 3O56 3O57 3W5E 4KP6
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abrogated  advance  amplified  bad  bcl  conferred  discovered  doi  emergence  frame  her2  inactivated  june  lapatinib  onc  oncogene  online  permitting  phosphoinositide  pim1  publication  reading  rescue  rescued  restored  sensitized  trastuzumab  uncover  xl 
acrdy2  acrodysostosis  allosteric  augmenting  closing  cognition  consolidation  cr3  dampening  discover  elucidation  intellectual  mechanistically  mim  modulators  monophosphate  nams  neuroinflammation  nonamyloid  pde4a  pde4d  phosphodiesterase  positron  strict  ucr2  ultra  underexploited  underscored 
Tagcloud (Difference) ?
abrogated  advance  amplified  bad  bcl  conferred  discovered  doi  emergence  frame  her2  inactivated  june  lapatinib  onc  oncogene  online  permitting  phosphoinositide  pim1  publication  reading  rescue  rescued  restored  sensitized  trastuzumab  uncover  xl 
acrdy2  acrodysostosis  allosteric  augmenting  closing  cognition  consolidation  cr3  dampening  discover  elucidation  intellectual  mechanistically  mim  modulators  monophosphate  nams  neuroinflammation  nonamyloid  pde4a  pde4d  phosphodiesterase  positron  strict  ucr2  ultra  underexploited  underscored 
Tagcloud (Intersection) ?