PRKACA and HMGCR

  • Number of citations of the paper that reports this interaction (PMID 2369897)
  • 45
  • Data Source:
  • HPRD (in vitro, in vivo)

PRKACA

HMGCR

Gene Name protein kinase, cAMP-dependent, catalytic, alpha 3-hydroxy-3-methylglutaryl-CoA reductase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 181 interactors: AANAT ABCA1 ACLY ADCY5 ADD1 ADD2 ADRBK1 AKAP13 AKAP14 AKAP8L AKIP1 ANXA7 APC APOBEC3G ASIC1 ASIC3 ATF1 ATP2B1 AURKA BAD BCL2 BRAF CACNA1C CACNB2 CACNG2 CAD CALD1 CAMKK2 CCDC88A CCND1 CDK16 CETN1 CFTR CIITA CLDN3 CLTC CREB1 CREM CSK CUL5 CYP3A4 DMTN DNAJC5 DSP EEF2K EGFR ESR1 ETV1 FOS FXYD1 GABRB3 GABRR1 GAD1 GAD2 GFAP GJA5 GJB1 GMFB GNA13 GNMT GP1BB GRIA1 GRIA4 GSK3A GSK3B GUSB GYS1 HAND1 HAND2 HDAC1 HDAC8 HMGCR HMGN1 HMGN2 HNRNPD HSPD1 IFNAR1 IQGAP1 IRF2 ITCH ITGA2B ITGA4 ITPKA ITPKB ITPR1 ITPR2 KCNH2 KCNJ12 KCNQ1 KLF1 LCK LCP1 LIPE LRP1 MAP2 MAP3K3 MAPT MBP MC4R MEF2D MEP1B MGMT MIP NDRG1 NFKB1 NIN NOLC1 NOS1 NOXA1 NR3C1 NUP85 PARK2 PDC PDE3B PDE4B PDE4D PDPK1 PFKFB1 PFKFB2 PHKA1 PHOX2A PKIA PLIN1 PLN POU2F1 PPP1R10 PPP1R17 PPP1R1B PPP1R8 PPP1R9B PRKAR1A PSEN1 PTBP1 PTPN12 PTPN13 PTPN7 PTPRR RAF1 RANBP9 RAP1A RAP1B RAP1GAP RASGRF1 RASGRP3 RELA RGS10 RGS13 RGS14 RHOA RRAD RSBN1 RYR1 RYR2 SI SIK1 SIK3 SLC2A2 SLC4A4 SLC9A3R2 SNAP25 SNAPIN SPTBN1 SRC STK11 STMN1 STMN2 SYN1 SYN2 TBXA2R TCF3 TH THOP1 TNP1 TNP2 TPH1 TRIP10 UHRF1 VASP VIM VTN WT1 4 interactors: ARHGAP1 INSIG1 PRKACA STARD13
Entrez ID 5566 3156
HPRD ID 03382 00836
Ensembl ID ENSG00000072062 ENSG00000113161
Uniprot IDs P17612 P04035
PDB IDs 2GU8 3AGL 3AGM 3AMA 3AMB 3L9L 3L9M 3L9N 3MVJ 3NX8 3OOG 3OVV 3OWP 3OXT 3P0M 3POO 3VQH 4AE6 4AE9 1DQ8 1DQ9 1DQA 1HW8 1HW9 1HWI 1HWJ 1HWK 1HWL 2Q1L 2Q6B 2Q6C 2R4F 3BGL 3CCT 3CCW 3CCZ 3CD0 3CD5 3CD7 3CDA 3CDB
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abrogated  advance  amplified  bad  bcl  conferred  discovered  doi  emergence  frame  her2  inactivated  june  lapatinib  onc  oncogene  online  permitting  phosphoinositide  pim1  publication  reading  rescue  rescued  restored  sensitized  trastuzumab  uncover  xl 
7b  alteration  alters  bh3  biosynthesis  cholesterol  chop  clues  downregulation  ebp  emerged  foxj2  h460  hmgcs1  idi1  inverse  let  lna  mirna  mirnas  mirnome  nac  nci  played  respective  scavenger  silencing  stat6  utr 
Tagcloud (Difference) ?
abrogated  advance  amplified  bad  bcl  conferred  discovered  doi  emergence  frame  her2  inactivated  june  lapatinib  onc  oncogene  online  permitting  phosphoinositide  pim1  publication  reading  rescue  rescued  restored  sensitized  trastuzumab  uncover  xl 
7b  alteration  alters  bh3  biosynthesis  cholesterol  chop  clues  downregulation  ebp  emerged  foxj2  h460  hmgcs1  idi1  inverse  let  lna  mirna  mirnas  mirnome  nac  nci  played  respective  scavenger  silencing  stat6  utr 
Tagcloud (Intersection) ?