Wiki-Pi
About
Search
People
Updates
Search
GSK3A and NBR1
Number of citations of the paper that reports this interaction (PubMedID
20368287
)
102
Data Source:
BioGRID
(two hybrid, affinity chromatography technology, proximity labelling technology, affinity chromatography technology, enzymatic study, affinity chromatography technology)
GSK3A
NBR1
Description
glycogen synthase kinase 3 alpha
NBR1 autophagy cargo receptor
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrion
Cytosol
Axon
Beta-catenin Destruction Complex
Neuronal Cell Body
Apical Dendrite
Postsynapse
Proximal Dendrite
Phagophore Assembly Site
Nucleoplasm
Cytoplasm
Mitochondrion
Mitochondrial Intermembrane Space
Lysosome
Late Endosome
Autophagosome
Peroxisomal Membrane
Cytosol
Membrane
Nuclear Body
Cytoplasmic Vesicle
M Band
Receptor Complex
Intracellular Organelle Lumen
Molecular Function
Nucleotide Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Signaling Receptor Binding
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Protein Kinase A Catalytic Subunit Binding
Tau Protein Binding
Tau-protein Kinase Activity
Protein Serine Kinase Activity
Protein Binding
Zinc Ion Binding
Ubiquitin Binding
Metal Ion Binding
Mitogen-activated Protein Kinase Binding
Biological Process
Regulation Of Systemic Arterial Blood Pressure
Cardiac Left Ventricle Morphogenesis
Glycogen Metabolic Process
Nervous System Development
Insulin Receptor Signaling Pathway
Negative Regulation Of Signal Transduction
Positive Regulation Of Autophagy
Positive Regulation Of Gene Expression
Negative Regulation Of UDP-glucose Catabolic Process
Regulation Of Neuron Projection Development
Wnt Signaling Pathway
Cell Migration
Viral Protein Processing
Cell Differentiation
Positive Regulation Of Protein Ubiquitination
Lipopolysaccharide-mediated Signaling Pathway
Negative Regulation Of TOR Signaling
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Insulin Stimulus
Cellular Response To Interleukin-3
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Neuron Apoptotic Process
Negative Regulation Of Glycogen Biosynthetic Process
Positive Regulation Of Protein Catabolic Process
Positive Regulation Of Heart Contraction
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of D-glucose Import
Negative Regulation Of Insulin Receptor Signaling Pathway
Excitatory Postsynaptic Potential
Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development
Regulation Of Microtubule Cytoskeleton Organization
Cellular Response To Lithium Ion
Cellular Response To Glucocorticoid Stimulus
Positive Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Negative Regulation Of Canonical Wnt Signaling Pathway
Extrinsic Apoptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Autosome Genomic Imprinting
Beta-arrestin-dependent Dopamine Receptor Signaling Pathway
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Mitophagy
Cellular Response To Oxygen-containing Compound
Positive Regulation Of Amyloid-beta Formation
Positive Regulation Of Protein Targeting To Mitochondrion
Positive Regulation Of Establishment Of Protein Localization
Negative Regulation Of Type B Pancreatic Cell Development
Negative Regulation Of Glycogen (starch) Synthase Activity
Macroautophagy
Regulation Of Bone Mineralization
Regulation Of Stress-activated MAPK Cascade
Negative Regulation Of Osteoblast Differentiation
Pathways
AKT phosphorylates targets in the cytosol
XBP1(S) activates chaperone genes
Constitutive Signaling by AKT1 E17K in Cancer
Suppression of apoptosis
Maturation of nucleoprotein
Maturation of nucleoprotein
Pexophagy
Pexophagy
Drugs
Fostamatinib
Diseases
GWAS
Meat-related diet (
32066663
)
Interacting Genes
76 interacting genes:
AKAP11
AKT1
ALKBH3
AP3D1
AURKAIP1
BCCIP
BCL2L1
BCL3
BICD1
C11orf98
CCDC174
CHTOP
CNTROB
CREB1
CREM
DCAF8
DDI1
DEAF1
DNAJB1
DRC1
EBNA1BP2
EIF2B5
FAM193B
GLI3
GOLGA6C
H2AZ2
HMBS
HMGN1
HNRNPM
HSF1
HSP90AA1
HSP90AB1
LCOR
LDHA
LRP6
LRRC37A2
LRSAM1
MAEA
MAPT
MCL1
MTCH1
MYC
MYL12A
NBR1
OGT
PRKACA
PRKCA
PRKCB
PRKCD
PRKCG
PRKCH
PRKCZ
PRKD3
PRKDC
PSMD8
PTMA
PXN
RICTOR
RPL15
RPL19
RPL29
RPS15
RPS19
RUNX1
SBNO1
SGK1
SGK3
SMARCA5
SMG7
SPG21
STAT2
SUGP2
TTC16
UBTF
VCPIP1
YWHAG
22 interacting genes:
ACAD10
ATXN1L
AXIN1
CALM1
CIB1
FEZ1
GABARAP
GABARAPL2
GSK3A
GSK3B
ITSN2
MAP1LC3A
MAP2K4
METAP1
SQSTM1
SYT4
TTN
UBC
UBE2D2
UBE2D3
USP8
VTA1
Entrez ID
2931
4077
HPRD ID
06002
01326
Ensembl ID
ENSG00000105723
ENSG00000188554
Uniprot IDs
P49840
B7Z5R6
Q14596
PDB IDs
7SXF
7SXG
1WJ6
2BKF
2CP8
2G4S
2L8J
2MGW
2MJ5
4OLE
Enriched GO Terms of Interacting Partners
?
Diacylglycerol-dependent Serine/threonine Kinase Activity
Response To Peptide Hormone
Negative Regulation Of Apoptotic Process
Cytosol
Negative Regulation Of Programmed Cell Death
Regulation Of Programmed Cell Death
Response To Heat
Regulation Of Apoptotic Process
Response To Hormone
Macromolecule Metabolic Process
Nucleoplasm
Protein Phosphorylation
Protein Serine Kinase Activity
Nucleus
Cytoplasmic Translation
Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity
Cellular Response To Heat
Phosphorylation
Protein Serine/threonine Kinase Activity
Cellular Response To Stress
Protein Kinase C Signaling
Response To Temperature Stimulus
Positive Regulation Of Immune System Process
Cytoplasm
Protein Metabolic Process
Cellular Response To Peptide Hormone Stimulus
Response To Stress
Intracellular Signal Transduction
Protein Kinase Activity
Leukocyte Apoptotic Process
Positive Regulation Of Leukocyte Differentiation
Translation
Macromolecule Biosynthetic Process
Positive Regulation Of Protein Localization
Positive Regulation Of Metabolic Process
Nitric-oxide Synthase Regulator Activity
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Translation
Cellular Response To Oxygen-containing Compound
Protein Serine/threonine/tyrosine Kinase Activity
CAMP/PKA Signal Transduction
DNA Damage Response
Negative Regulation Of Glial Cell Apoptotic Process
Regulation Of Protein Localization
Nucleic Acid Metabolic Process
Regulation Of Cellular Component Organization
Regulation Of Immune System Process
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Regulation Of Metabolic Process
Kinase Activity
Ubiquitin Protein Ligase Binding
Cellular Response To Nitrogen Starvation
Beta-catenin Destruction Complex
Regulation Of Protein Localization
Catabolic Process
Mitophagy
Phosphatidylethanolamine Binding
Negative Regulation Of Type B Pancreatic Cell Development
Negative Regulation Of Glycogen (starch) Synthase Activity
Macroautophagy
Organelle Organization
Autophagy Of Mitochondrion
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Autophagosome
Regulation Of Protein Ubiquitination
Regulation Of Proteasomal Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Regulation Of Protein Catabolic Process
Proteolysis
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Protein Ubiquitination
Regulation Of Glycogen (starch) Synthase Activity
Cytosol
Regulation Of Post-translational Protein Modification
Positive Regulation Of Proteasomal Protein Catabolic Process
Extrinsic Apoptotic Signaling Pathway
Beta-arrestin-dependent Dopamine Receptor Signaling Pathway
Proteolysis Involved In Protein Catabolic Process
Organelle Assembly
Positive Regulation Of Post-translational Protein Modification
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Sperm Midpiece
Cellular Response To Interleukin-3
Autophagy
Protein-containing Complex Disassembly
Autophagosome Maturation
Regulation Of Establishment Of Protein Localization
Positive Regulation Of Establishment Of Protein Localization
Regulation Of Type B Pancreatic Cell Development
Autophagosome Membrane
Apoptotic Signaling Pathway
Negative Regulation Of Glycogen Biosynthetic Process
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Vesicle
Negative Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Modification Process
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?