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GSK3A and RPS15
Number of citations of the paper that reports this interaction (PubMedID
30824926
)
69
Data Source:
BioGRID
(two hybrid)
GSK3A
RPS15
Description
glycogen synthase kinase 3 alpha
ribosomal protein S15
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrion
Cytosol
Axon
Beta-catenin Destruction Complex
Neuronal Cell Body
Apical Dendrite
Postsynapse
Proximal Dendrite
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Ribosome
Focal Adhesion
Small Ribosomal Subunit
Membrane
Cytosolic Ribosome
Cytosolic Small Ribosomal Subunit
Synapse
Ribonucleoprotein Complex
Molecular Function
Nucleotide Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Signaling Receptor Binding
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Protein Kinase A Catalytic Subunit Binding
Tau Protein Binding
Tau-protein Kinase Activity
Protein Serine Kinase Activity
DNA Binding
RNA Binding
Structural Constituent Of Ribosome
Protein Binding
MDM2/MDM4 Family Protein Binding
Ubiquitin Ligase Inhibitor Activity
Biological Process
Regulation Of Systemic Arterial Blood Pressure
Cardiac Left Ventricle Morphogenesis
Glycogen Metabolic Process
Nervous System Development
Insulin Receptor Signaling Pathway
Negative Regulation Of Signal Transduction
Positive Regulation Of Autophagy
Positive Regulation Of Gene Expression
Negative Regulation Of UDP-glucose Catabolic Process
Regulation Of Neuron Projection Development
Wnt Signaling Pathway
Cell Migration
Viral Protein Processing
Cell Differentiation
Positive Regulation Of Protein Ubiquitination
Lipopolysaccharide-mediated Signaling Pathway
Negative Regulation Of TOR Signaling
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Insulin Stimulus
Cellular Response To Interleukin-3
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Neuron Apoptotic Process
Negative Regulation Of Glycogen Biosynthetic Process
Positive Regulation Of Protein Catabolic Process
Positive Regulation Of Heart Contraction
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of D-glucose Import
Negative Regulation Of Insulin Receptor Signaling Pathway
Excitatory Postsynaptic Potential
Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development
Regulation Of Microtubule Cytoskeleton Organization
Cellular Response To Lithium Ion
Cellular Response To Glucocorticoid Stimulus
Positive Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway
Negative Regulation Of Canonical Wnt Signaling Pathway
Extrinsic Apoptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Autosome Genomic Imprinting
Beta-arrestin-dependent Dopamine Receptor Signaling Pathway
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Regulation Of Mitophagy
Cellular Response To Oxygen-containing Compound
Positive Regulation Of Amyloid-beta Formation
Positive Regulation Of Protein Targeting To Mitochondrion
Positive Regulation Of Establishment Of Protein Localization
Negative Regulation Of Type B Pancreatic Cell Development
Negative Regulation Of Glycogen (starch) Synthase Activity
Ribosomal Small Subunit Assembly
Ribosomal Small Subunit Export From Nucleus
Osteoblast Differentiation
Cytoplasmic Translation
RRNA Processing
Translation
Ribosomal Small Subunit Biogenesis
Liver Regeneration
Positive Regulation Of Signal Transduction By P53 Class Mediator
Pathways
AKT phosphorylates targets in the cytosol
XBP1(S) activates chaperone genes
Constitutive Signaling by AKT1 E17K in Cancer
Suppression of apoptosis
Maturation of nucleoprotein
Maturation of nucleoprotein
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
SARS-CoV-1 modulates host translation machinery
SARS-CoV-2 modulates host translation machinery
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Fostamatinib
Diseases
GWAS
Meat-related diet (
32066663
)
Hematocrit (
32888494
)
Hemoglobin (
32888494
)
Red blood cell count (
32888494
)
Interacting Genes
76 interacting genes:
AKAP11
AKT1
ALKBH3
AP3D1
AURKAIP1
BCCIP
BCL2L1
BCL3
BICD1
C11orf98
CCDC174
CHTOP
CNTROB
CREB1
CREM
DCAF8
DDI1
DEAF1
DNAJB1
DRC1
EBNA1BP2
EIF2B5
FAM193B
GLI3
GOLGA6C
H2AZ2
HMBS
HMGN1
HNRNPM
HSF1
HSP90AA1
HSP90AB1
LCOR
LDHA
LRP6
LRRC37A2
LRSAM1
MAEA
MAPT
MCL1
MTCH1
MYC
MYL12A
NBR1
OGT
PRKACA
PRKCA
PRKCB
PRKCD
PRKCG
PRKCH
PRKCZ
PRKD3
PRKDC
PSMD8
PTMA
PXN
RICTOR
RPL15
RPL19
RPL29
RPS15
RPS19
RUNX1
SBNO1
SGK1
SGK3
SMARCA5
SMG7
SPG21
STAT2
SUGP2
TTC16
UBTF
VCPIP1
YWHAG
15 interacting genes:
CDC42
DUX4
ERCC6
G2E3
GSK3A
GSK3B
NAP1L1
PLA2G12A
PTEN
RAPGEF1
RPS4X
SERINC3
TNFAIP3
UBC
UPF2
Entrez ID
2931
6209
HPRD ID
06002
01613
Ensembl ID
ENSG00000105723
ENSG00000115268
Uniprot IDs
P49840
K7ELC2
P62841
PDB IDs
7SXF
7SXG
4UG0
4V6X
5A2Q
5AJ0
5FLX
5LKS
5OA3
5T2C
5VYC
6FEC
6G18
6G4S
6G4W
6G51
6G53
6G5H
6G5I
6IP5
6IP6
6IP8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6XA1
6Y0G
6Y2L
6Y57
6YBS
6Z6L
6Z6M
6Z6N
6ZLW
6ZM7
6ZME
6ZMI
6ZMO
6ZMT
6ZMW
6ZN5
6ZOJ
6ZOL
6ZON
6ZP4
6ZUO
6ZV6
6ZVH
6ZVJ
6ZXD
6ZXE
6ZXF
6ZXG
6ZXH
7A09
7K5I
7QP6
7QP7
7R4X
7TQL
7WTT
7WTU
7WTV
7WTW
7WTX
7WTZ
7WU0
7XNX
7XNY
8G5Y
8G60
8G61
8G6J
8GLP
8IFD
8IFE
8JDJ
8JDK
8JDL
8JDM
8K2C
8OZ0
8PJ1
8PJ2
8PJ3
8PJ4
8PJ5
8PJ6
8PPK
8PPL
8QOI
8T4S
8UKB
8XP2
8XP3
8XSX
8XSY
8XSZ
8XXL
8XXM
8XXN
8Y0W
8Y0X
8YOO
8YOP
8ZDB
8ZDC
8ZDD
9BKD
9BLN
9C3H
9G8M
9G8O
Enriched GO Terms of Interacting Partners
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Diacylglycerol-dependent Serine/threonine Kinase Activity
Response To Peptide Hormone
Negative Regulation Of Apoptotic Process
Cytosol
Negative Regulation Of Programmed Cell Death
Regulation Of Programmed Cell Death
Response To Heat
Regulation Of Apoptotic Process
Response To Hormone
Macromolecule Metabolic Process
Nucleoplasm
Protein Phosphorylation
Protein Serine Kinase Activity
Nucleus
Cytoplasmic Translation
Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity
Cellular Response To Heat
Phosphorylation
Protein Serine/threonine Kinase Activity
Cellular Response To Stress
Protein Kinase C Signaling
Response To Temperature Stimulus
Positive Regulation Of Immune System Process
Cytoplasm
Protein Metabolic Process
Cellular Response To Peptide Hormone Stimulus
Response To Stress
Intracellular Signal Transduction
Protein Kinase Activity
Leukocyte Apoptotic Process
Positive Regulation Of Leukocyte Differentiation
Translation
Macromolecule Biosynthetic Process
Positive Regulation Of Protein Localization
Positive Regulation Of Metabolic Process
Nitric-oxide Synthase Regulator Activity
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Translation
Cellular Response To Oxygen-containing Compound
Protein Serine/threonine/tyrosine Kinase Activity
CAMP/PKA Signal Transduction
DNA Damage Response
Negative Regulation Of Glial Cell Apoptotic Process
Regulation Of Protein Localization
Nucleic Acid Metabolic Process
Regulation Of Cellular Component Organization
Regulation Of Immune System Process
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Regulation Of Metabolic Process
Kinase Activity
Nervous System Development
Negative Regulation Of Type B Pancreatic Cell Development
Negative Regulation Of Glycogen (starch) Synthase Activity
Regulation Of Glycogen (starch) Synthase Activity
Neuron Projection Organization
Beta-arrestin-dependent Dopamine Receptor Signaling Pathway
System Development
Cellular Response To Interleukin-3
Regulation Of Type B Pancreatic Cell Development
Negative Regulation Of Glycogen Biosynthetic Process
Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Cytoplasm
Regulation Of Cell-substrate Adhesion
Positive Regulation Of Protein Metabolic Process
Cytoplasmic Ribonucleoprotein Granule
Beta-catenin Destruction Complex
Protein Kinase A Catalytic Subunit Binding
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Dendritic Spine Morphogenesis
Membrane Organization
Regulation Of Plasma Membrane Bounded Cell Projection Organization
Positive Regulation Of Cell-substrate Adhesion
Regulation Of Protein Modification Process
Tau-protein Kinase Activity
Regulation Of Cell Projection Organization
Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Viral Protein Processing
Positive Regulation Of Mitochondrial Membrane Permeability
Regulation Of Peptidyl-serine Phosphorylation
Regulation Of Glycogen Biosynthetic Process
Positive Regulation Of Membrane Permeability
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Dendritic Spine Organization
Negative Regulation Of Organ Growth
Regulation Of Neuron Projection Development
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Regulation Of Glycogen Metabolic Process
Intracellular Signaling Cassette
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Regulation Of Protein Ubiquitination
Neuron Projection Development
Postsynapse Organization
Regulation Of Defense Response To Virus By Host
Tau Protein Binding
Positive Regulation Of Proteolysis
Negative Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Cell Population Proliferation
Negative Regulation Of UDP-glucose Catabolic Process
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Tagcloud (Intersection)
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