CCNG1 and PPP2R4

Number of citations of the paper that reports this interaction (PMID 8887688)
13

Data Source:
BioGRID (two hybrid)
HPRD (in vivo, in vitro)

		CCNG1	PPP2R4
Gene Name		cyclin G1	protein phosphatase 2A activator, regulatory subunit 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Dendrite Neuronal Cell Body Perinuclear Region Of Cytoplasm	Protein Phosphatase Type 2A Complex Nucleus Nucleoplasm Cytoplasm Calcium Channel Complex Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Receptor Binding ATP Binding Protein Tyrosine Phosphatase Activator Activity Protein Phosphatase Type 2A Regulator Activity ATPase Activity Protein Homodimerization Activity Protein Heterodimerization Activity Protein Phosphatase 2A Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Syncytium Formation Mitotic Nuclear Division Mitotic G2 DNA Damage Checkpoint Brain Development Response To Organonitrogen Compound Cell Growth Negative Regulation Of Apoptotic Process Cell Division	Protein Peptidyl-prolyl Isomerization Metabolic Process Mitotic Spindle Organization In Nucleus Negative Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Dephosphorylation Positive Regulation Of Apoptotic Process Regulation Of Phosphoprotein Phosphatase Activity
Pathways
Drugs
Diseases
GWAS			Hypersomnia (HLA-DQB1*06:02 negative) ( 23646285)
Protein-Protein Interactions		25 interactors: APP CDK5 CDKN2A COX2 GAK GRN HMBOX1 KRT40 KRTAP10-7 LTBP3 LZTS2 MDM2 NFATC4 PAK7 PLEKHA4 PNMA1 PPP2CA PPP2R4 RBPMS SHKBP1 SPERT TFAP2C TFIP11 TNIP1 TP53	19 interactors: AKT1 AMOT APP AURKB BCL2 CCNG1 CCNG2 CSNK2A1 CYLD EIF4EBP1 H2AFX HDAC4 MAPT MID1 PIM1 PPP2R3A PRKCB RACGAP1 SRC
Entrez ID		900	5524
HPRD ID		03345	02858
Ensembl ID		ENSG00000113328	ENSG00000119383
Uniprot IDs		P51959	B4DZF8 Q15257
PDB IDs			2G62 2HV6 2HV7 2IXM
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Metabolic Process Cellular Response To UV Response To Light Stimulus Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Signal Transduction Regulation Of Nucleocytoplasmic Transport Apoptotic Process Cellular Response To Light Stimulus Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Arrest Programmed Cell Death Regulation Of Intracellular Transport Positive Regulation Of Intracellular Transport Cell Death Response To Radiation Death Regulation Of Apoptotic Process Negative Regulation Of Cell Differentiation Regulation Of Cell Proliferation Regulation Of Protein Export From Nucleus Regulation Of Intracellular Protein Transport Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Signaling Regulation Of Cell Death Regulation Of Protein Localization Response To UV Cellular Response To Radiation Learning Positive Regulation Of Protein Metabolic Process Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Cell Aging Negative Regulation Of Cell Growth Positive Regulation Of Intracellular Protein Transport Cell Cycle Neuron Apoptotic Process Regulation Of Establishment Of Protein Localization Mitotic Cell Cycle Process Regulation Of Cellular Localization Neuron Death Regulation Of Phosphorus Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Positive Regulation Of Cell Cycle Arrest Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Negative Regulation Of Cell Cycle	Regulation Of Cell Cycle Cell Cycle Regulation Of Organelle Organization Mitotic Cell Cycle Process Positive Regulation Of Cell Cycle Cell Cycle Process Mitotic Cell Cycle Regulation Of Metabolic Process Regulation Of Mitotic Cell Cycle Programmed Cell Death Cell Death Death Regulation Of Cellular Component Organization Organelle Organization Multicellular Organismal Development Regulation Of Microtubule Cytoskeleton Organization Regulation Of Protein Binding Regulation Of Signal Transduction Regulation Of Microtubule-based Process Apoptotic Process Developmental Process Regulation Of Signaling Cellular Response To Stimulus Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Cycle Checkpoint Regulation Of Cell Cycle Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Binding Response To Stress Regulation Of Protein Metabolic Process Peptidyl-serine Phosphorylation Regulation Of Cytoskeleton Organization Positive Regulation Of Cell Growth Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Process Nervous System Development Positive Regulation Of Signal Transduction Protein Phosphorylation Regulation Of Catalytic Activity Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intracellular Signal Transduction Cell Growth Negative Regulation Of Mitochondrial Depolarization Regulation Of Growth Negative Regulation Of Cell Death Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Protein Modification Process
Tagcloud ?		abcb4 akr7a3 anabolic bioassay built carcinogenic carcinogenicity carcinogens cdkn1a dataset datasets employs formally gates generalizable informative integrates mathematical methodologies nongenotoxic omics phlda3 rankings reproducible rodent signatures subsamplings toxicogenomics virtue	al355149 algorithm annotation array cisplatin dataset deregulated deregulation existing fam46a fluorouracil lnc lncrna lncrnas man1a2 mbl2 microdissected ncfans nodal noticed paclitaxel reannotation reserve scc sprr2d stxbp5 tongue tumorigenic validate
Tagcloud (Difference) ?		abcb4 akr7a3 anabolic bioassay built carcinogenic carcinogenicity carcinogens cdkn1a datasets employs formally gates generalizable informative integrates mathematical methodologies nongenotoxic omics phlda3 rankings reproducible rodent signatures subsamplings toxicogenomics virtue	al355149 algorithm annotation array cisplatin deregulated deregulation existing fam46a fluorouracil lnc lncrna lncrnas man1a2 mbl2 microdissected ncfans nodal noticed paclitaxel reannotation reserve scc sprr2d stxbp5 tongue tumorigenic validate
Tagcloud (Intersection) ?		dataset