WEE2-AS1 and HSPA8

Number of citations of the paper that reports this interaction (PubMedID 36123327)
40

Data Source:
BioGRID (unspecified method)

		WEE2-AS1	HSPA8
Description		WEE2 antisense RNA 1	heat shock protein family A (Hsp70) member 8
Image		No pdb structure
GO Annotations	Cellular Component	U1 SnRNP	Prp19 Complex Extracellular Region Extracellular Space Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Lysosome Lysosomal Membrane Cytosol Plasma Membrane Focal Adhesion Membrane Secretory Granule Lumen Melanosome Lysosomal Lumen Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Extracellular Exosome Blood Microparticle Lumenal Side Of Lysosomal Membrane Protein Folding Chaperone Complex Ficolin-1-rich Granule Lumen Ribonucleoprotein Complex
	Molecular Function	Pre-mRNA 5'-splice Site Binding	Nucleotide Binding G Protein-coupled Receptor Binding RNA Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Enzyme Binding MHC Class II Protein Complex Binding Protein-macromolecule Adaptor Activity Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Protein Folding Chaperone Cadherin Binding Receptor Ligand Activity Unfolded Protein Binding Protein-folding Chaperone Binding C3HC4-type RING Finger Domain Binding ATP-dependent Protein Disaggregase Activity ATP-dependent Protein Folding Chaperone
	Biological Process	MRNA 5'-splice Site Recognition	MRNA Splicing, Via Spliceosome MRNA Processing Protein Folding Autophagy Response To Unfolded Protein Signal Transduction RNA Splicing Cellular Response To Starvation Negative Regulation Of Signal Transduction Protein Catabolic Process Positive Regulation Of Cell Migration Regulation Of Protein Stability Cellular Response To Stress Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Protein Refolding Regulation Of Protein-containing Complex Assembly Negative Regulation Of DNA-templated Transcription ATP Metabolic Process Negative Regulation Of Cellular Component Organization Membrane Organization Regulation Of Protein Complex Stability Chaperone-mediated Autophagy Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy Cellular Response To Steroid Hormone Stimulus Clathrin Coat Disassembly Negative Regulation Of NLRP3 Inflammasome Complex Assembly Regulation Of Supramolecular Fiber Organization Negative Regulation Of Supramolecular Fiber Organization Regulation Of Protein Import Chaperone-mediated Autophagy Translocation Complex Disassembly
Pathways			Regulation of HSF1-mediated heat shock response HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Attenuation phase HSF1-dependent transactivation Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis CHL1 interactions AUF1 (hnRNP D0) binds and destabilizes mRNA Interleukin-4 and Interleukin-13 signaling Neutrophil degranulation mRNA Splicing - Major Pathway Clathrin-mediated endocytosis Protein methylation GABA synthesis, release, reuptake and degradation Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy Respiratory syncytial virus genome transcription PKR-mediated signaling
Drugs			Dasatinib (2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol Copper Artenimol
Diseases
GWAS			Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 29403010 32888494) Postoperative acute renal failure after cardiac surgery ( 30678657) Red cell distribution width ( 32888494) Serum metabolite levels ( 33031748)
Interacting Genes		161 interacting genes: AASS ACSL3 ACTG1 AGAP1 AHNAK AJUBA AKAP11 ALB ALKBH4 ANXA2 ARL6IP4 ASPSCR1 ATAD3A BCLAF1 BRAT1 CALML5 CLPB COPB2 COPG1 CSTF1 CTNND1 CTU2 DAXX DDX1 DDX23 DIDO1 DLST DNAAF5 DOHH DPYSL4 DSC1 DSP EEF1A1 EGR2 EIF3A ELL EMD EPM2AIP1 ERAP1 ERH EXOC4 FAM120B FAM83H FLG FLG2 FMR1 FOXK1 FXR1 FXR2 GAB1 GAPDH GBF1 GNL3 GRB10 GSDME GSN GTF3C1 GTPBP1 GTSE1 HARS1 HAX1 HMGA1 HMGCS1 HNRNPA2B1 HNRNPC HNRNPH1 HNRNPH2 HNRNPLL HNRNPM HSP90AA1 HSP90AB1 HSPA6 HSPA8 HSPB1 IFIT1 IGF2BP1 IGF2BP3 KCTD3 KIF20A KIF22 LAMC1 LARP7 LDLR LUC7L2 MAGED2 MAP1A MED23 MINDY3 MOB1A MSH6 MYH9 MYO1C NCKAP1 NDFIP1 NEK9 NISCH NPM1 NUP160 NXF1 PABPC1 PALS2 PARP1 PCMT1 PDCD2L PDXP PIGU PJA2 PLEC POP1 PPL PPM1F PRKAR2A PSMB1 PSMD1 PTK2 QTRT2 RAB5A RAF1 RETREG2 RPL13 RPLP2 RPN2 RPP30 RPRD1B RPS17 RPS2 RPS28 RPS29 RPS8 S100A14 S100A7 SEC13 SERBP1 SHKBP1 SHTN1 SKIC2 SLC25A11 SLC27A3 SNX8 SQSTM1 SRP68 STAT5B TANK THBS1 THRAP3 TIMELESS TMPO TOR1AIP2 TPR TRIM21 TRIM56 TRMT10C TTC28 TUBA1B TUBB3 TUBB4B U2AF1 UBB USP1 XRCC6 YBX1	92 interacting genes: ABI1 AIPL1 ALDOB APOB ATM BAG1 BAG2 BAG3 BAG4 BAG6 BRCA1 CCT3 CD40 CDKN2A CITED1 CLTA COL7A1 CXCR4 CYCS DNAJA1 DNAJA3 DPP3 DYNLL1 EGFR ERBB3 ERH ESR1 FANCC FBP1 FNDC3B FOXP1 GAK GCH1 GOT2 H3C1 HDAC10 HDAC3 HGS HLTF HSF1 HSP90AA1 HSPA1A HSPBP1 HSPH1 HTN3 HTT IL32 JAK2 JUN LALBA LINC01554 MAPK8 MAPT NEDD8 NMI NOA1 PHC1 PPID PTEN PTPRF RAF1 RB1 REL RGS2 RNF26 SAYSD1 SIRPA SNCA SP1 SRRT ST13 STAT1 STIP1 STMN1 STUB1 SUMO2 SUMO4 TADA3 TCERG1 TGM2 TM4SF1 TNFRSF1A TRIM38 TSSK6 TTC1 UBC UCHL1 USP40 VHL WEE2-AS1 YWHAG YWHAQ
Entrez ID		285962	3312
HPRD ID		08286	07205
Ensembl ID		ENSG00000228775	ENSG00000109971
Uniprot IDs			P11142 Q53HF2 V9HW22
PDB IDs			3AGY 3AGZ 3ESK 3FZF 3FZH 3FZK 3FZL 3FZM 3LDQ 3M3Z 4H5N 4H5R 4H5T 4H5V 4H5W 4HWI 4KBQ 5AQF 5AQG 5AQH 5AQI 5AQJ 5AQK 5AQL 5AQM 5AQN 5AQO 5AQP 5AQQ 5AQR 5AQS 5AQT 5AQU 5AQV 6B1I 6B1M 6B1N 6ZYJ
Enriched GO Terms of Interacting Partners?		RNA Binding Cytosol Ribonucleoprotein Complex Cytoplasm Nucleus Focal Adhesion Extracellular Exosome Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Nucleic Acid Metabolic Process RNA Metabolic Process Regulation Of Protein Metabolic Process Cytoplasmic Stress Granule MRNA Binding N6-methyladenosine-containing RNA Reader Activity Protein Binding MRNA Processing RNA Transport Nucleolus MRNA Transport Biological_process RNA Processing Nucleic Acid Binding Cellular Response To Heat Translation Regulator Activity Positive Regulation Of Protein Metabolic Process Nucleoplasm Positive Regulation Of Metabolic Process Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Cornified Envelope Positive Regulation Of Macromolecule Metabolic Process MRNA Metabolic Process Positive Regulation Of Biosynthetic Process Response To Heat Regulation Of Translation Regulation Of MRNA Stability CRD-mediated MRNA Stabilization Ficolin-1-rich Granule Lumen MRNA 3'-UTR Binding Nucleobase-containing Compound Transport Regulation Of RNA Stability Negative Regulation Of MRNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Ubiquitin Protein Ligase Binding Structural Molecule Activity Positive Regulation Of Gene Expression RNA Splicing Cadherin Binding Negative Regulation Of MRNA Catabolic Process Regulation Of Plasma Membrane Organization	Ubiquitin Protein Ligase Binding Regulation Of Protein Stability Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Protein Folding Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Protein Stabilization Negative Regulation Of Apoptotic Process Enzyme Binding Response To Stress Negative Regulation Of Programmed Cell Death Cytosol Apoptotic Process Programmed Cell Death Positive Regulation Of Macromolecule Metabolic Process Cell Death Positive Regulation Of Programmed Cell Death Adenyl-nucleotide Exchange Factor Activity Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Primary Metabolic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Metabolic Process Regulation Of Signal Transduction Negative Regulation Of Signal Transduction Regulation Of Protein Modification Process Heat Shock Protein Binding Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Multicellular Organismal Process Hsp70 Protein Binding Cellular Response To Stress Regulation Of Signaling Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Communication Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Protein Folding Chaperone Complex Negative Regulation Of Intracellular Signal Transduction Response To Heat Cellular Response To Oxygen-containing Compound Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Catabolic Process Nucleus Response To Peptide Positive Regulation Of Protein Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?