HSPA8 and STMN1

Number of citations of the paper that reports this interaction (PMID 10197448)
3

Data Source:
BioGRID (pull down)
HPRD (in vivo, in vitro)

		HSPA8	STMN1
Gene Name		heat shock 70kDa protein 8	stathmin 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Prp19 Complex Extracellular Space Intracellular Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytosol Plasma Membrane Focal Adhesion Membrane Ribonucleoprotein Complex Melanosome Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Extracellular Vesicular Exosome Blood Microparticle	Intracellular Cytoplasm Cytosol Microtubule Membrane Neuron Projection Extracellular Vesicular Exosome
	Molecular Function	G-protein Coupled Receptor Binding Protein Binding ATP Binding ATPase Activity Enzyme Binding MHC Class II Protein Complex Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding ATPase Activity, Coupled Poly(A) RNA Binding Unfolded Protein Binding	Signal Transducer Activity Tubulin Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription, DNA-templated Protein Folding Post-Golgi Vesicle-mediated Transport Response To Unfolded Protein Synaptic Transmission Neurotransmitter Secretion Axon Guidance RNA Splicing Gene Expression Viral Process Cellular Response To Heat Protein Refolding Negative Regulation Of Transcription, DNA-templated Positive Regulation Of MRNA Splicing, Via Spliceosome Chaperone Mediated Protein Folding Requiring Cofactor Regulation Of Cell Cycle Membrane Organization Clathrin Coat Disassembly Regulation Of Cellular Response To Heat Negative Regulation Of Fibril Organization	Microtubule Depolymerization Mitotic Spindle Organization Signal Transduction Axonogenesis Brain Development Response To Virus Negative Regulation Of Microtubule Polymerization Neuron Projection Development Intracellular Signal Transduction Positive Regulation Of Cellular Component Movement Regulation Of Cytoskeleton Organization
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing Regulation of mRNA stability by proteins that bind AU-rich elements Axon guidance Golgi Associated Vesicle Biogenesis Attenuation phase mRNA Splicing - Major Pathway L1CAM interactions Regulation of HSF1-mediated heat shock response Cellular response to heat stress AUF1 (hnRNP D0) destabilizes mRNA GABA synthesis, release, reuptake and degradation Clathrin derived vesicle budding Lysosome Vesicle Biogenesis HSF1-dependent transactivation Neurotransmitter Release Cycle CHL1 interactions trans-Golgi Network Vesicle Budding Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		83 interactors: ABI1 AIPL1 ALDOB APOB BAG1 BAG2 BAG3 BAG4 BAG6 BRCA1 CAPZA1 CAPZB CCAR2 CCT3 CD40 CDKN2A CITED1 CLTA COL7A1 CXCR4 CYCS DNAJA1 DNAJA3 DNAJB1 DNAJC7 DPP3 DYNLL1 EGFR ERH ESR1 FANCC FBP1 GAK GCH1 GOT2 HDAC10 HDAC3 HGS HLTF HSF1 HSP90AA1 HSPA1A HSPBP1 HSPH1 HTT IL32 JAK2 JUN LALBA MAPK8 MAPT METTL21A NMI NOA1 PHC1 PPID RAF1 RB1 REL RGS2 SGTA SNCA SP1 SRRT ST13 STIP1 STMN1 STUB1 SUMO4 TADA3 TCERG1 TCP1 TGM2 TM4SF1 TNFRSF1A TRIM38 TSSK6 TTC1 UBC UCHL1 VHL YWHAG YWHAQ	16 interactors: CAMK2G CDK1 CDKN1B CSNK2A1 GLP1R HSPA5 HSPA8 MAPK3 PRKACA RLIM SEPT2 SESTD1 SIVA1 STAT3 UBQLN4 UHMK1
Entrez ID		3312	3925
HPRD ID		07205	01047
Ensembl ID		ENSG00000109971	ENSG00000117632
Uniprot IDs		P11142 Q53HF2	P16949
PDB IDs		3AGY 3AGZ 3ESK 3FZF 3FZH 3FZK 3FZL 3FZM 3LDQ 3M3Z 4HWI
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Death Protein Folding Regulation Of Apoptotic Process Apoptotic Process Programmed Cell Death Cell Death Death Protein Refolding Response To Stress Regulation Of Signal Transduction Response To Stimulus Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cell Death Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Response To Organic Substance Cellular Response To Stimulus Regulation Of Signaling Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Response To Abiotic Stimulus Protein Metabolic Process Regulation Of Protein Stability Regulation Of Protein Phosphorylation Negative Regulation Of Signal Transduction Regulation Of Phosphorus Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Catalytic Activity Negative Regulation Of Protein Metabolic Process Apoptotic Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorylation Negative Regulation Of Signaling Defense Response Chaperone Cofactor-dependent Protein Refolding Regulation Of Intracellular Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter Signal Transduction Positive Regulation Of Signal Transduction Cell Communication Cellular Response To Organic Substance Protein Complex Assembly Negative Regulation Of Phosphorylation Positive Regulation Of Cellular Metabolic Process	Nervous System Development Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Response To Peptide Hormone Response To Peptide Cell Cycle Regulation Of Cellular Response To Heat Cellular Response To Peptide Hormone Stimulus Regulation Of Metabolic Process Cellular Response To Peptide Cell Cycle Process Mitotic Cell Cycle Process Neuron Differentiation Cell Surface Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Protein Catabolic Process System Development Mitotic Cell Cycle Positive Regulation Of Protein Metabolic Process Cell Development Response To Organic Substance Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Intracellular Transport Response To Fibroblast Growth Factor Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Cellular Response To Organic Substance Neuron Projection Development Response To Organonitrogen Compound Signaling Cellular Response To Organonitrogen Compound Protein Autophosphorylation Regulation Of Cellular Protein Metabolic Process Cell Communication Cellular Response To Heat Regulation Of Cell Cycle Multicellular Organismal Development Response To Hormone Neuron Development Apoptotic Process Anatomical Structure Development Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell Death Regulation Of Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Phase Transition Regulation Of Cell Death Generation Of Neurons
Tagcloud ?		alteration cadherin cd133 cognate ectopically electrophoresis filament glioblastoma glioblastomas gliomas hairpin hsc71 interfere invasion modulating nanog nestin oct overexpress progenitor restored shrna sphere stemness suppresses transfected transfection tumorigenic vi	actb assessments bestkeeper brca1 colon ercc1 esophageal gapdh gastrointestinal genorm gusb normalized normfinder optimal personalized qrt ranking rectal reference represented rplpo rrm1 separately taqman tfrc top2a tubb3 tyms vegfr2
Tagcloud (Difference) ?		alteration cadherin cd133 cognate ectopically electrophoresis filament glioblastoma glioblastomas gliomas hairpin hsc71 interfere invasion modulating nanog nestin oct overexpress progenitor restored shrna sphere stemness suppresses transfected transfection tumorigenic vi	actb assessments bestkeeper brca1 colon ercc1 esophageal gapdh gastrointestinal genorm gusb normalized normfinder optimal personalized qrt ranking rectal reference represented rplpo rrm1 separately taqman tfrc top2a tubb3 tyms vegfr2
Tagcloud (Intersection) ?