WEE2-AS1 and SRP68

Number of citations of the paper that reports this interaction (PubMedID 36168628)
47

Data Source:
BioGRID (unspecified method)

		WEE2-AS1	SRP68
Description		WEE2 antisense RNA 1	signal recognition particle 68
Image		No pdb structure
GO Annotations	Cellular Component	U1 SnRNP	Nucleus Nucleolus Cytoplasm Endoplasmic Reticulum Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Ribosome Focal Adhesion Signal Recognition Particle Ribonucleoprotein Complex
	Molecular Function	Pre-mRNA 5'-splice Site Binding	RNA Binding Signal Recognition Particle Binding Protein Binding 7S RNA Binding Protein Domain Specific Binding Endoplasmic Reticulum Signal Peptide Binding Ribosome Binding
	Biological Process	MRNA 5'-splice Site Recognition	SRP-dependent Cotranslational Protein Targeting To Membrane Response To Xenobiotic Stimulus
Pathways			SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS
Interacting Genes		161 interacting genes: AASS ACSL3 ACTG1 AGAP1 AHNAK AJUBA AKAP11 ALB ALKBH4 ANXA2 ARL6IP4 ASPSCR1 ATAD3A BCLAF1 BRAT1 CALML5 CLPB COPB2 COPG1 CSTF1 CTNND1 CTU2 DAXX DDX1 DDX23 DIDO1 DLST DNAAF5 DOHH DPYSL4 DSC1 DSP EEF1A1 EGR2 EIF3A ELL EMD EPM2AIP1 ERAP1 ERH EXOC4 FAM120B FAM83H FLG FLG2 FMR1 FOXK1 FXR1 FXR2 GAB1 GAPDH GBF1 GNL3 GRB10 GSDME GSN GTF3C1 GTPBP1 GTSE1 HARS1 HAX1 HMGA1 HMGCS1 HNRNPA2B1 HNRNPC HNRNPH1 HNRNPH2 HNRNPLL HNRNPM HSP90AA1 HSP90AB1 HSPA6 HSPA8 HSPB1 IFIT1 IGF2BP1 IGF2BP3 KCTD3 KIF20A KIF22 LAMC1 LARP7 LDLR LUC7L2 MAGED2 MAP1A MED23 MINDY3 MOB1A MSH6 MYH9 MYO1C NCKAP1 NDFIP1 NEK9 NISCH NPM1 NUP160 NXF1 PABPC1 PALS2 PARP1 PCMT1 PDCD2L PDXP PIGU PJA2 PLEC POP1 PPL PPM1F PRKAR2A PSMB1 PSMD1 PTK2 QTRT2 RAB5A RAF1 RETREG2 RPL13 RPLP2 RPN2 RPP30 RPRD1B RPS17 RPS2 RPS28 RPS29 RPS8 S100A14 S100A7 SEC13 SERBP1 SHKBP1 SHTN1 SKIC2 SLC25A11 SLC27A3 SNX8 SQSTM1 SRP68 STAT5B TANK THBS1 THRAP3 TIMELESS TMPO TOR1AIP2 TPR TRIM21 TRIM56 TRMT10C TTC28 TUBA1B TUBB3 TUBB4B U2AF1 UBB USP1 XRCC6 YBX1	10 interacting genes: ABI1 CEBPA CFTR OGT RBFOX2 RNF10 SRP72 SUMO2 UBQLN2 WEE2-AS1
Entrez ID		285962	6730
HPRD ID		08286	05331
Ensembl ID		ENSG00000228775	ENSG00000167881
Uniprot IDs			Q9UHB9
PDB IDs			4P3E 4P3F 5M72 5M73 5WRV 7NFX 7QWQ 8QVW 8QVX
Enriched GO Terms of Interacting Partners?		RNA Binding Cytosol Ribonucleoprotein Complex Cytoplasm Nucleus Focal Adhesion Extracellular Exosome Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Nucleic Acid Metabolic Process RNA Metabolic Process Regulation Of Protein Metabolic Process Cytoplasmic Stress Granule MRNA Binding N6-methyladenosine-containing RNA Reader Activity Protein Binding MRNA Processing RNA Transport Nucleolus MRNA Transport Biological_process RNA Processing Nucleic Acid Binding Cellular Response To Heat Translation Regulator Activity Positive Regulation Of Protein Metabolic Process Nucleoplasm Positive Regulation Of Metabolic Process Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Cornified Envelope Positive Regulation Of Macromolecule Metabolic Process MRNA Metabolic Process Positive Regulation Of Biosynthetic Process Response To Heat Regulation Of Translation Regulation Of MRNA Stability CRD-mediated MRNA Stabilization Ficolin-1-rich Granule Lumen MRNA 3'-UTR Binding Nucleobase-containing Compound Transport Regulation Of RNA Stability Negative Regulation Of MRNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Ubiquitin Protein Ligase Binding Structural Molecule Activity Positive Regulation Of Gene Expression RNA Splicing Cadherin Binding Negative Regulation Of MRNA Catabolic Process Regulation Of Plasma Membrane Organization	Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Chromatin DNA Binding Response To Vitamin B2 C/EBP Complex Regulation Of Protein Metabolic Process Positive Regulation Of Anion Channel Activity Negative Regulation Of G Protein-coupled Receptor Internalization CHOP-C/EBP Complex Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Monoatomic Anion Transport Protein O-acetylglucosaminyltransferase Activity Sterol Metabolic Process Cholesterol Metabolic Process White Fat Cell Proliferation Positive Regulation Of Enamel Mineralization Negative Regulation Of Clathrin-dependent Endocytosis Pre-mRNA 5'-splice Site Binding Positive Regulation Of Macromolecule Metabolic Process Response To Phenylpropanoid Positive Regulation Of Catabolic Process Response To Nutrient Positive Regulation Of Transcription By RNA Polymerase II Cell Maturation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Fat Cell Proliferation Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization
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