GPR17 and GNA13

Number of citations of the paper that reports this interaction (PMID 9092554)
15

Data Source:
HPRD (in vivo)

		GPR17	GNA13
Gene Name		G protein-coupled receptor 17	guanine nucleotide binding protein (G protein), alpha 13
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Nucleus Heterotrimeric G-protein Complex Plasma Membrane Focal Adhesion Membrane Brush Border Membrane Melanosome Extracellular Vesicular Exosome
	Molecular Function	Chemokine Receptor Activity	GTPase Activity Signal Transducer Activity Protein Binding GTP Binding G-protein Beta/gamma-subunit Complex Binding Type 1 Angiotensin Receptor Binding D5 Dopamine Receptor Binding Metal Ion Binding
	Biological Process	G-protein Coupled Receptor Signaling Pathway Chemokine-mediated Signaling Pathway	Patterning Of Blood Vessels In Utero Embryonic Development Movement Of Cell Or Subcellular Component Signal Transduction Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Rho Protein Signal Transduction Blood Coagulation Regulation Of Cell Shape Cell Differentiation Platelet Activation Regulation Of Cell Migration Activation Of Phospholipase D Activity
Pathways		G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Nucleotide-like (purinergic) receptors Class A/1 (Rhodopsin-like receptors) GPCR ligand binding Metabolic disorders of biological oxidation enzymes P2Y receptors G alpha (q) signalling events GPCR downstream signaling Leukotriene receptors Gastrin-CREB signalling pathway via PKC and MAPK G alpha (i) signalling events Eicosanoid ligand-binding receptors	Thrombin signalling through proteinase activated receptors (PARs) Signaling by GPCR GPCR downstream signaling Thromboxane signalling through TP receptor G alpha (12/13) signalling events Signal amplification Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: GNA13	31 interactors: AIP AKAP3 ARHGEF1 ARHGEF11 ARHGEF12 CDH1 CDH2 CTNNB1 CXCR4 DRD5 EDNRB F2R GNA12 GPR17 MCF2 MTNR1A PPP5C PRKACA PRKCB PRKCD PRKCE PTK2B RDX RGS16 RIC8A S1PR2 S1PR3 S1PR4 TBXA2R TGFBR1 TSHR
Entrez ID		2840	10672
HPRD ID		04351	05100
Ensembl ID		ENSG00000144230	ENSG00000120063
Uniprot IDs		G4XH68 Q13304	B7Z7R0 F5H1G8 Q14344
PDB IDs
Enriched GO Terms of Interacting Partners?		Activation Of Phospholipase D Activity Patterning Of Blood Vessels Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Rho Protein Signal Transduction Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Cell Shape Cytosolic Calcium Ion Homeostasis Platelet Activation Branching Morphogenesis Of An Epithelial Tube Ras Protein Signal Transduction Morphogenesis Of A Branching Epithelium Morphogenesis Of A Branching Structure Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Angiogenesis Epithelial Tube Morphogenesis Cellular Metal Ion Homeostasis Blood Coagulation Blood Vessel Morphogenesis Hemostasis Tube Morphogenesis Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Regulation Of Cell Morphogenesis Pattern Specification Process Morphogenesis Of An Epithelium In Utero Embryonic Development Blood Vessel Development Cellular Chemical Homeostasis Vasculature Development	Cell Surface Receptor Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Signal Transduction Positive Regulation Of Catalytic Activity Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis G-protein Coupled Receptor Signaling Pathway Signaling Regulation Of Signaling Cell Communication Regulation Of Catalytic Activity Regulation Of Signal Transduction Cellular Response To Stimulus Cytosolic Calcium Ion Homeostasis Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Response To Organic Substance Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Activation Cellular Chemical Homeostasis Ion Homeostasis Apoptotic Process Programmed Cell Death Response To Stimulus Positive Regulation Of Hydrolase Activity Cellular Response To Organic Substance Cell Death Death Chemical Homeostasis Cellular Homeostasis Regulation Of Cellular Process G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Intracellular Signal Transduction Regulation Of Metabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of MAPK Cascade Regulation Of MAPK Cascade Platelet Activation Homeostatic Process Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Signaling Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Neurotrophin Signaling Pathway Positive Regulation Of Cellular Metabolic Process Termination Of Signal Transduction
Tagcloud ?		allocate arrangements barr cxcr2 dictate docking dogma ebi2 epstein fil gpcr gpcrs hormonal neurodegeneration neurotransmitter operate operated oxysterols participating pharmacology phylogenetically potently promiscuously rouge share spatiotemporal thresholds transversal unspecific	18q 19p13 1q aberrations arising burkitt collaborating cooperate copy deep enhancer gains id3 immunoglobulin lymphoma microrna myc next profiling recurrent scope sequencing signatures smarca4 subgroups summary transcriptome widened yielded
Tagcloud (Difference) ?		allocate arrangements barr cxcr2 dictate docking dogma ebi2 epstein fil gpcr gpcrs hormonal neurodegeneration neurotransmitter operate operated oxysterols participating pharmacology phylogenetically potently promiscuously rouge share spatiotemporal thresholds transversal unspecific	18q 19p13 1q aberrations arising burkitt collaborating cooperate copy deep enhancer gains id3 immunoglobulin lymphoma microrna myc next profiling recurrent scope sequencing signatures smarca4 subgroups summary transcriptome widened yielded
Tagcloud (Intersection) ?