GPR17

Description		G protein-coupled receptor 17
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GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Chemokine Receptor Activity Protein Binding Receptor Serine/threonine Kinase Binding
	Biological Process	Negative Regulation Of Inflammatory Response To Antigenic Stimulus Signal Transduction G Protein-coupled Receptor Signaling Pathway Oligodendrocyte Differentiation Chemokine-mediated Signaling Pathway
Pathways		Leukotriene receptors G alpha (q) signalling events P2Y receptors G alpha (i) signalling events
Drugs		Uridine diphosphate glucose Uridine-5'-Diphosphate Galactose-uridine-5'-diphosphate
Diseases
GWAS		Proportion of activated microglia (inferior temporal cortex) ( 30679421)
Novel Interacting Genes		1 novel interacting genes: GLA
Interacting Genes		2 interacting genes: GNA13 GPR37
Entrez ID		2840
HPRD ID		04351
Ensembl ID		ENSG00000144230
Uniprot IDs		G4XH68 Q13304
PDB IDs		7Y89
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Nitric-oxide Synthase Activity Alpha-galactosidase Activity Prosaposin Receptor Activity D5 Dopamine Receptor Binding Glycosylceramide Catabolic Process Regulation Of Nitric-oxide Synthase Activity Glycoside Catabolic Process Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Dopamine Metabolic Process Locomotion Involved In Locomotory Behavior Rho-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Oxidoreductase Activity Dopamine Biosynthetic Process Glycosylceramide Metabolic Process Glycosphingolipid Catabolic Process Glycolipid Catabolic Process Ceramide Catabolic Process Negative Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Oxidoreductase Activity Regulation Of Dopamine Metabolic Process Catecholamine Biosynthetic Process Neuropeptide Receptor Activity Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding Neuropeptide Binding Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Peptide Binding G Protein-coupled Receptor Signaling Pathway Amine Biosynthetic Process Biogenic Amine Biosynthetic Process Dopamine Metabolic Process Branching Involved In Blood Vessel Morphogenesis Heterotrimeric G-protein Complex Sphingolipid Catabolic Process G Protein-coupled Peptide Receptor Activity Membrane Lipid Catabolic Process Dendrite Development Catecholamine Metabolic Process Regulation Of Fibroblast Migration Regulation Of Postsynapse Assembly Hsp70 Protein Binding Glycosphingolipid Metabolic Process Brush Border Membrane Oligosaccharide Metabolic Process Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Nitric Oxide Metabolic Process Biogenic Amine Metabolic Process Heat Shock Protein Binding Rho Protein Signal Transduction Platelet Activation
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