SGSM3 and RAB5B

Number of citations of the paper that reports this interaction (PMID 16923123)
31

Data Source:
BioGRID (two hybrid)

		SGSM3	RAB5B
Gene Name		small G protein signaling modulator 3	RAB5B, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Intracellular Endosome Early Endosome Plasma Membrane Membrane Endocytic Vesicle Early Endosome Membrane Melanosome Extracellular Vesicular Exosome
	Molecular Function	Rab GTPase Activator Activity Protein Binding Rab GTPase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding GTP-dependent Protein Binding
	Biological Process	Cell Cycle Arrest Regulation Of Rab Protein Signal Transduction Rap Protein Signal Transduction Positive Regulation Of Rab GTPase Activity Plasma Membrane To Endosome Transport Regulation Of Cilium Assembly	Intracellular Protein Transport Endosome Organization Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Plasma Membrane To Endosome Transport
Pathways
Drugs
Diseases
GWAS		Height ( 19570815)	Polycystic ovary syndrome ( 22885925) Type 1 diabetes ( 18198356) Vitiligo ( 22951725)
Protein-Protein Interactions		7 interactors: GJA1 NF2 RAB39B RAB5A RAB5B RAB5C RPL35	15 interactors: APOA5 CDK1 CHM EEA1 RAB7A RABAC1 REEP5 RIN1 RIN2 RIN3 SGSM3 SUN2 TBC1D15 TBC1D17 TFRC
Entrez ID		27352	5869
HPRD ID		15285	01544
Ensembl ID		ENSG00000100359	ENSG00000111540
Uniprot IDs		B4DMS2 B4DVE3 B9A6J5 Q96HU1	P61020
PDB IDs			2HEI
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Ras Protein Signal Transduction Plasma Membrane To Endosome Transport Intracellular Protein Transport Cellular Protein Localization Protein Transport Small GTPase Mediated Signal Transduction Regulation Of Endocytosis Establishment Of Protein Localization Intracellular Transport Endosomal Transport Cytoplasmic Transport Protein Localization Regulation Of Cellular Component Organization Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Cellular Localization Milk Ejection Vascular Transport Lens Development In Camera-type Eye Negative Regulation Of DNA Metabolic Process Vesicle-mediated Transport Transport Atrial Ventricular Junction Remodeling Positive Regulation Of Cell Communication By Chemical Coupling Regulation Of Cellular Component Movement Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Endosome Size Intracellular Signal Transduction Cell Communication By Chemical Coupling Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Negative Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Cell-cell Junction Organization ATP Transport Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Positive Regulation Of Glomerular Filtration Schwann Cell Proliferation Positive Regulation Of Behavioral Fear Response Adenine Nucleotide Transport Regulation Of Hippo Signaling Regulation Of Cellular Localization Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Atrial Cardiac Muscle Cell Action Potential Purine Nucleotide Transport Atrial Cardiac Muscle Cell To AV Node Cell Communication Regulation Of Tight Junction Assembly Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Secretion Regulation Of Glomerular Filtration Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization	Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Positive Regulation Of Catalytic Activity Positive Regulation Of Hydrolase Activity Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Vesicle-mediated Transport Endocytosis Regulation Of Catalytic Activity Positive Regulation Of Ras GTPase Activity Endosomal Transport Regulation Of Ras GTPase Activity Organelle Fusion Regulation Of Ras Protein Signal Transduction Positive Regulation Of Metabolic Process Regulation Of Small GTPase Mediated Signal Transduction Transport Early Endosome To Late Endosome Transport Membrane Organization Regulation Of Signaling Cellular Localization Ras Protein Signal Transduction Regulation Of Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Vesicle Fusion Protein Localization Regulation Of Signal Transduction Establishment Of Localization In Cell Synaptic Vesicle To Endosome Fusion Pronuclear Fusion Epidermal Growth Factor Catabolic Process Retrograde Transport, Endosome To Golgi Nuclear Envelope Organization Organ Regeneration Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Intracellular Transport Nuclear Matrix Organization Negative Regulation Of Synaptic Plasticity Nuclear Matrix Anchoring At Nuclear Membrane Nucleus Organization Phagosome-lysosome Fusion Nuclear Migration Along Microfilament Regulation Of Metabolic Process Membrane Fusion Phagosome Acidification Protein Localization To Organelle Regulation Of Schwann Cell Differentiation Protein Geranylgeranylation Protein To Membrane Docking
Tagcloud ?		athanogene bag3 bcl2 cancerous developmentally e3 fnbp4 formin guanylatekinase ligase magi1 modulator nedd4 oncogene oncogenic oxidoreductase pdz property rab2a tumorigenic unchanged wbp2 wbp2nl ww wwox wwp1 wwtr1 yap1 yes
Tagcloud (Difference) ?		athanogene bag3 bcl2 cancerous developmentally e3 fnbp4 formin guanylatekinase ligase magi1 modulator nedd4 oncogene oncogenic oxidoreductase pdz property rab2a tumorigenic unchanged wbp2 wbp2nl ww wwox wwp1 wwtr1 yap1 yes
Tagcloud (Intersection) ?