SGSM3 and RAB5C

Number of citations of the paper that reports this interaction (PMID 16923123)
31

Data Source:
BioGRID (two hybrid)

		SGSM3	RAB5C
Gene Name		small G protein signaling modulator 3	RAB5C, member RAS oncogene family
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol	Lysosomal Membrane Early Endosome Lipid Particle Plasma Membrane Endocytic Vesicle Early Endosome Membrane Melanosome Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Rab GTPase Activator Activity Protein Binding Rab GTPase Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Cell Cycle Arrest Regulation Of Rab Protein Signal Transduction Rap Protein Signal Transduction Positive Regulation Of Rab GTPase Activity Plasma Membrane To Endosome Transport Regulation Of Cilium Assembly	Intracellular Protein Transport Regulation Of Endocytosis Rab Protein Signal Transduction Plasma Membrane To Endosome Transport
Pathways			Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Height ( 19570815)
Protein-Protein Interactions		7 interactors: GJA1 NF2 RAB39B RAB5A RAB5B RAB5C RPL35	10 interactors: APP APPL2 EEA1 RABAC1 RBSN RIN2 RIN3 SGSM3 TBC1D15 TBC1D17
Entrez ID		27352	5878
HPRD ID		15285	04947
Ensembl ID		ENSG00000100359	ENSG00000108774
Uniprot IDs		B4DMS2 B4DVE3 B9A6J5 Q96HU1	P51148
PDB IDs
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Ras Protein Signal Transduction Plasma Membrane To Endosome Transport Intracellular Protein Transport Cellular Protein Localization Protein Transport Small GTPase Mediated Signal Transduction Regulation Of Endocytosis Establishment Of Protein Localization Intracellular Transport Endosomal Transport Cytoplasmic Transport Protein Localization Regulation Of Cellular Component Organization Establishment Of Localization In Cell Regulation Of Vesicle-mediated Transport Cellular Localization Milk Ejection Vascular Transport Lens Development In Camera-type Eye Negative Regulation Of DNA Metabolic Process Vesicle-mediated Transport Transport Atrial Ventricular Junction Remodeling Positive Regulation Of Cell Communication By Chemical Coupling Regulation Of Cellular Component Movement Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Endosome Size Intracellular Signal Transduction Cell Communication By Chemical Coupling Negative Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Negative Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Cell-cell Junction Organization ATP Transport Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Positive Regulation Of Glomerular Filtration Schwann Cell Proliferation Positive Regulation Of Behavioral Fear Response Adenine Nucleotide Transport Regulation Of Hippo Signaling Regulation Of Cellular Localization Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization Atrial Cardiac Muscle Cell Action Potential Purine Nucleotide Transport Atrial Cardiac Muscle Cell To AV Node Cell Communication Regulation Of Tight Junction Assembly Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Secretion Regulation Of Glomerular Filtration Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization	Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Positive Regulation Of Ras GTPase Activity Positive Regulation Of Hydrolase Activity Regulation Of Ras GTPase Activity Regulation Of Catalytic Activity Regulation Of Ras Protein Signal Transduction Vesicle-mediated Transport Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Catalytic Activity Regulation Of GTPase Activity Regulation Of Signal Transduction Regulation Of Signaling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Endosomal Transport Endocytosis Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Regulation Of Intracellular Signal Transduction Mating Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Metabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Regulation Of ERBB Signaling Pathway Synaptic Vesicle To Endosome Fusion Feeding Behavior Cholesterol Metabolic Process Synaptic Growth At Neuromuscular Junction Regulation Of Receptor Activity Sterol Metabolic Process Neuromuscular Process Intracellular Transport Collateral Sprouting In Absence Of Injury Regulation Of Protein Binding Transition Metal Ion Homeostasis Transport Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Peptidyl-tyrosine Phosphorylation Axon Choice Point Recognition Plasma Membrane To Endosome Transport Locomotory Behavior Establishment Of Localization In Cell
Tagcloud ?		athanogene bag3 bcl2 cancerous developmentally e3 fnbp4 formin guanylatekinase ligase magi1 modulator nedd4 oncogene oncogenic oxidoreductase pdz property rab2a tumorigenic unchanged wbp2 wbp2nl ww wwox wwp1 wwtr1 yap1 yes	cdc42 compartment coordinately cytomegalovirus ectopic encode golgi hcmv herpesviruses infectious micrornas mirna mirnas mirs morphogenesis noninfectious rab11a reorganization resemble secretory sirnas snap23 stacks ul112 uncovered us5 vac vamp3 virion
Tagcloud (Difference) ?		athanogene bag3 bcl2 cancerous developmentally e3 fnbp4 formin guanylatekinase ligase magi1 modulator nedd4 oncogene oncogenic oxidoreductase pdz property rab2a tumorigenic unchanged wbp2 wbp2nl ww wwox wwp1 wwtr1 yap1 yes	cdc42 compartment coordinately cytomegalovirus ectopic encode golgi hcmv herpesviruses infectious micrornas mirna mirnas mirs morphogenesis noninfectious rab11a reorganization resemble secretory sirnas snap23 stacks ul112 uncovered us5 vac vamp3 virion
Tagcloud (Intersection) ?