MON1B and VPS18

Number of citations of the paper that reports this interaction (PMID 20434987)
96

Data Source:
BioGRID (two hybrid, pull down)

		MON1B	VPS18
Gene Name		MON1 secretory trafficking family member B	vacuolar protein sorting 18 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endomembrane System	Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Actin Filament HOPS Complex Late Endosome Membrane
	Molecular Function	Protein Binding	Actin Binding Protein Binding Syntaxin Binding Protein Binding, Bridging Metal Ion Binding
	Biological Process	Vesicle-mediated Transport	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Endosome Organization Lysosome Organization Regulation Of SNARE Complex Assembly Viral Entry Into Host Cell
Pathways
Drugs
Diseases
GWAS			Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-Protein Interactions		6 interactors: RABGEF1 VPS11 VPS16 VPS18 VPS33A VPS41	18 interactors: AKTIP COPB1 EP300 GGA1 GGA2 GGA3 HOOK1 MON1B STX1A STX6 STX7 STX8 UBE2D2 UVRAG VPS11 VPS16 VPS33A VPS45
Entrez ID		22879	57617
HPRD ID		12342	09776
Ensembl ID			ENSG00000104142
Uniprot IDs		B4DDZ0 E7EW32 Q6ZR87 Q7L1V2	Q9P253
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of SNARE Complex Assembly Protein Transport Establishment Of Protein Localization Regulation Of Vesicle Fusion Protein Localization Establishment Of Localization In Cell Intracellular Protein Transport Regulation Of Vesicle-mediated Transport Cellular Localization Cellular Protein Localization Vesicle-mediated Transport Intracellular Transport Viral Entry Into Host Cell Entry Into Host Cell Regulation Of Protein Complex Assembly Transport Vesicle Docking Involved In Exocytosis Vesicle Docking Membrane Docking Negative Regulation Of Kit Signaling Pathway Regulation Of Vacuole Fusion, Non-autophagic Vacuole Fusion, Non-autophagic Interaction With Host Vacuole Organization Regulation Of Cellular Component Organization Viral Life Cycle Regulation Of Organelle Organization Negative Regulation Of Mast Cell Degranulation Negative Regulation Of Interleukin-6 Secretion Negative Regulation Of Mast Cell Activation Involved In Immune Response Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Negative Regulation Of Mast Cell Activation Exocytosis Protein Targeting Negative Regulation Of Receptor-mediated Endocytosis Regulation Of Vacuole Organization Negative Regulation Of Leukocyte Migration Platelet Formation Platelet Morphogenesis Protein Targeting To Vacuole Regulation Of Developmental Pigmentation Regulation Of Mast Cell Degranulation Secretion By Cell Establishment Of Protein Localization To Vacuole Viral Process Endosome Organization Lysosome Localization Regulation Of Mast Cell Activation Negative Regulation Of Cytokine Secretion Negative Regulation Of Interleukin-6 Production	Vesicle-mediated Transport Protein Transport Establishment Of Protein Localization Protein Localization Intracellular Transport Establishment Of Localization In Cell Intracellular Protein Transport Cellular Localization Vesicle Fusion Cellular Protein Localization Transport Organelle Fusion Vesicle Organization Membrane Fusion Vesicle Docking Endosomal Transport Early Endosome To Late Endosome Transport Membrane Docking Endosome To Lysosome Transport Endosome Organization Lysosomal Transport Vesicle Docking Involved In Exocytosis Membrane Organization Vacuolar Transport Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Organelle Organization Organelle Localization Viral Entry Into Host Cell Entry Into Host Cell Vesicle Localization Viral Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Protein Localization To Plasma Membrane Histone H2B Acetylation Regulation Of Vacuole Fusion, Non-autophagic Positive Regulation Of Receptor Localization To Synapse Regulation Of DNA-templated Transcription In Response To Stress Lysosome Organization Positive Regulation Of Protein Binding Exocytosis N-terminal Peptidyl-lysine Acetylation Regulation Of Protein Localization Cellular Response To Hypoxia Regulation Of Vesicle-mediated Transport Cellular Response To Decreased Oxygen Levels Interaction With Host Vacuole Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Cellular Response To Oxygen Levels Regulation Of Tubulin Deacetylation
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