MON1B and VPS41

Number of citations of the paper that reports this interaction (PMID 20434987)
96

Data Source:
BioGRID (pull down)

		MON1B	VPS41
Gene Name		MON1 secretory trafficking family member B	vacuolar protein sorting 41 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endomembrane System	Lysosomal Membrane Early Endosome Late Endosome Golgi-associated Vesicle Cytosol Microtubule Cytoskeleton Membrane HOPS Complex CORVET Complex
	Molecular Function	Protein Binding	Molecular_function Protein Binding Microtubule Binding Zinc Ion Binding GTPase Binding
	Biological Process	Vesicle-mediated Transport	Protein Targeting To Vacuole Biological_process Vesicle-mediated Transport Regulation Of SNARE Complex Assembly Vacuole Fusion, Non-autophagic Golgi Vesicle Transport
Pathways
Drugs
Diseases
GWAS			Cognitive performance ( 19734545)
Protein-Protein Interactions		6 interactors: RABGEF1 VPS11 VPS16 VPS18 VPS33A VPS41	9 interactors: AKTIP AP3D1 APP HOOK1 HOOK2 HOOK3 MON1B UBE2U ZNF512B
Entrez ID		22879	27072
HPRD ID		12342	10402
Ensembl ID			ENSG00000006715
Uniprot IDs		B4DDZ0 E7EW32 Q6ZR87 Q7L1V2	E9PF36 P49754
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of SNARE Complex Assembly Protein Transport Establishment Of Protein Localization Regulation Of Vesicle Fusion Protein Localization Establishment Of Localization In Cell Intracellular Protein Transport Regulation Of Vesicle-mediated Transport Cellular Localization Cellular Protein Localization Vesicle-mediated Transport Intracellular Transport Viral Entry Into Host Cell Entry Into Host Cell Regulation Of Protein Complex Assembly Transport Vesicle Docking Involved In Exocytosis Vesicle Docking Membrane Docking Negative Regulation Of Kit Signaling Pathway Regulation Of Vacuole Fusion, Non-autophagic Vacuole Fusion, Non-autophagic Interaction With Host Vacuole Organization Regulation Of Cellular Component Organization Viral Life Cycle Regulation Of Organelle Organization Negative Regulation Of Mast Cell Degranulation Negative Regulation Of Interleukin-6 Secretion Negative Regulation Of Mast Cell Activation Involved In Immune Response Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Negative Regulation Of Mast Cell Activation Exocytosis Protein Targeting Negative Regulation Of Receptor-mediated Endocytosis Regulation Of Vacuole Organization Negative Regulation Of Leukocyte Migration Platelet Formation Platelet Morphogenesis Protein Targeting To Vacuole Regulation Of Developmental Pigmentation Regulation Of Mast Cell Degranulation Secretion By Cell Establishment Of Protein Localization To Vacuole Viral Process Endosome Organization Lysosome Localization Regulation Of Mast Cell Activation Negative Regulation Of Cytokine Secretion Negative Regulation Of Interleukin-6 Production	Early Endosome To Late Endosome Transport Endosome To Lysosome Transport Endosome Organization Lysosomal Transport Lysosome Organization Endosomal Transport Vacuolar Transport Vacuole Organization Vesicle-mediated Transport Endomembrane System Organization Cytoplasmic Transport Intracellular Transport Establishment Of Localization In Cell Cellular Localization Protein Transport Establishment Of Protein Localization Axon Cargo Transport Organelle Organization Protein Localization Transport Synaptic Growth At Neuromuscular Junction Synaptic Vesicle Membrane Organization Microtubule-based Transport Collateral Sprouting In Absence Of Injury Cytoskeleton-dependent Intracellular Transport Regulation Of Protein Binding Eye Pigment Biosynthetic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Sequestering Of Zinc Ion Microtubule-based Process Axon Choice Point Recognition Eye Pigmentation Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Positive Regulation Of NK T Cell Differentiation Pigment Granule Maturation Endosome To Melanosome Transport Neuron Remodeling Cellular Pigment Accumulation Regulation Of Binding Microtubule Anchoring At Centrosome Microtubule Anchoring At Microtubule Organizing Center Negative Regulation Of Neurogenesis Protein Localization To Centrosome Golgi Localization Microtubule-based Movement Negative Regulation Of Cell Development Cellular Copper Ion Homeostasis Interkinetic Nuclear Migration
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