GPKOW and NINL

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		GPKOW	NINL
Gene Name		G patch domain and KOW motifs	ninein-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Microtubule Organizing Center Cytosol Microtubule
	Molecular Function	Molecular_function Nucleic Acid Binding Protein Binding	Calcium Ion Binding
	Biological Process	Biological_process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization
Pathways			Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: APP BUD13 CCDC57 GOLGA2 NINL PPP1CA PRPF4 PRPF8 ROPN1 SH3GL1 TCEA2 TERF2IP TRAF2 TRIM23 WDR77 WDR83	45 interactors: AKAP17A APEX2 CCDC130 CCDC146 CCDC33 CCHCR1 CLEC1B DCTN5 EWSR1 EZH2 FAM107A FAM161A GCC1 GPKOW HAUS1 JUNB KANSL1 KAT5 KAT7 L3MBTL4 LRSAM1 LZTS2 MAD1L1 MBIP MCM10 PLK1 RBM41 RCOR3 RGS2 RIBC2 SH2D4A SH3BP5L SPERT SYT17 TCEANC TCEB3 TNNT1 TSPYL4 UTP14A ZFC3H1 ZFHX3 ZNF250 ZNF417 ZNF426 ZNF646
Entrez ID		27238	22981
HPRD ID		06737	11120
Ensembl ID			ENSG00000101004
Uniprot IDs		Q92917	Q9Y2I6
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing RNA Splicing Regulation Of Protein Binding RNA Metabolic Process Gene Expression Spliceosomal SnRNP Assembly Regulation Of Binding Negative Regulation Of DNA Recombination At Telomere Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Synaptic Growth At Neuromuscular Junction Nucleobase-containing Compound Metabolic Process Collateral Sprouting In Absence Of Injury Positive Regulation Of NF-kappaB Transcription Factor Activity Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Protection From Non-homologous End Joining At Telomere Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Peptidase Activity Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Telomere Capping Protein Localization To Chromosome, Telomeric Region Axon Choice Point Recognition Negative Regulation Of Glial Cell Apoptotic Process	RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Gene Expression Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Peptidyl-lysine Modification Protein Acetylation Cellular Nitrogen Compound Metabolic Process Chromatin Organization Protein Localization To Chromatin Chromosome Organization Cell Cycle Histone H4-K5 Acetylation Histone H4-K8 Acetylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Chromatin Modification Histone Modification Regulation Of Transcription, DNA-templated Negative Regulation Of Muscle Contraction Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Organelle Organization Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Protein Localization To Chromosome Cell Cycle Process Mitotic Spindle Checkpoint Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Chromosome Segregation Mitotic Nuclear Division Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Ubiquitin-dependent Endocytosis Regulation Of Metaphase Plate Congression Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Muscle Cell Differentiation Regulation Of Nitrogen Compound Metabolic Process
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